Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Johan K Sandberg"'
Autor:
Bonnie Bengtsson, Christopher Maucourant, Johan K Sandberg, Niklas K Björkström, Hannes Hagström
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0294695 (2024)
Background and aimsInfection is a serious complication in patients with cirrhosis. Mucosal-associated invariant T (MAIT) cells are involved in the immune defense against infections and known to be impaired in several chronic conditions, including cir
Externí odkaz:
https://doaj.org/article/75241782ae954a029ae9471c7474e565
Autor:
Caroline Boulouis, Wan Rong Sia, Muhammad Yaaseen Gulam, Jocelyn Qi Min Teo, Yi Tian Png, Thanh Kha Phan, Jeffrey Y W Mak, David P Fairlie, Ivan K H Poon, Tse Hsien Koh, Peter Bergman, Chwee Ming Lim, Lin-Fa Wang, Andrea Lay Hoon Kwa, Johan K Sandberg, Edwin Leeansyah
Publikováno v:
PLoS Biology, Vol 18, Iss 6, p e3000644 (2020)
Mucosa-associated invariant T (MAIT) cells are abundant antimicrobial T cells in humans and recognize antigens derived from the microbial riboflavin biosynthetic pathway presented by the MHC-Ib-related protein (MR1). However, the mechanisms responsib
Externí odkaz:
https://doaj.org/article/1a7439938aa940da856fd9dd1aad64f2
Autor:
Marcus Buggert, Son Nguyen, Laura M McLane, Maria Steblyanko, Nadia Anikeeva, Dominic Paquin-Proulx, Perla M Del Rio Estrada, Yuria Ablanedo-Terrazas, Kajsa Noyan, Morgan A Reuter, Korey Demers, Johan K Sandberg, Michael A Eller, Hendrik Streeck, Marianne Jansson, Piotr Nowak, Anders Sönnerborg, David H Canaday, Ali Naji, E John Wherry, Merlin L Robb, Steven G Deeks, Gustavo Reyes-Teran, Yuri Sykulev, Annika C Karlsson, Michael R Betts
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006973 (2018)
CD4+ T cells subsets have a wide range of important helper and regulatory functions in the immune system. Several studies have specifically suggested that circulating effector CD4+ T cells may play a direct role in control of HIV replication through
Externí odkaz:
https://doaj.org/article/df1780bbe6624538b6575e0b882c2f07
Publikováno v:
PLoS Biology, Vol 15, Iss 7, p e2003167 (2017)
The bacterium Staphylococcus aureus is an important cause of the life-threatening condition toxic shock syndrome in humans. Bacterial toxins known as superantigens (SAgs) generate this illness by acting as broad activators of a substantial fraction o
Externí odkaz:
https://doaj.org/article/e5adaaee95074c9f807d4f88ef27b48a
Autor:
Prossy Naluyima, Leigh Anne Eller, Benson J Ouma, Denis Kyabaggu, Peter Kataaha, David Guwatudde, Hannah Kibuuka, Fred Wabwire-Mangen, Merlin L Robb, Nelson L Michael, Mark S de Souza, Johan K Sandberg, Michael A Eller
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146196 (2016)
Management of patient care and interpretation of research data require evaluation of laboratory results in the context of reference data from populations with known health status to adequately diagnose disease or make a physiological assessment. Few
Externí odkaz:
https://doaj.org/article/5174abd58cda4ed986d2039bbd147e42
Autor:
Edwin Leeansyah, Jenny Svärd, Joana Dias, Marcus Buggert, Jessica Nyström, Máire F Quigley, Markus Moll, Anders Sönnerborg, Piotr Nowak, Johan K Sandberg
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005072 (2015)
Mucosa-associated invariant T (MAIT) cells represent a large innate-like evolutionarily conserved antimicrobial T-cell subset in humans. MAIT cells recognize microbial riboflavin metabolites from a range of microbes presented by MR1 molecules. MAIT c
Externí odkaz:
https://doaj.org/article/7f527c6195cb4b9397fe48033f417edd
Autor:
Kim Blom, Monika Braun, Jolita Pakalniene, Laura Dailidyte, Vivien Béziat, Margit H Lampen, Jonas Klingström, Nina Lagerqvist, Torbjörn Kjerstadius, Jakob Michaëlsson, Lars Lindquist, Hans-Gustaf Ljunggren, Johan K Sandberg, Aukse Mickiene, Sara Gredmark-Russ
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004622 (2015)
Tick-borne encephalitis virus (TBEV) is transferred to humans by ticks. The virus causes tick-borne encephalitis (TBE) with symptoms such as meningitis and meningoencephalitis. About one third of the patients suffer from long-lasting sequelae after c
Externí odkaz:
https://doaj.org/article/23f8c6d50176467c9f33f23bf9d4a0c6
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105665 (2014)
Soluble CD14 (sCD14) and IL-18 are markers and mediators of the innate immune response, and their plasma levels candidate biomarkers of HCV treatment effects and outcome. Here, we retrospectively studied sCD14 and IL-18 over the course of interferon-
Externí odkaz:
https://doaj.org/article/4e81d6d3619141b08bc7e1147dd98753
Autor:
Dominic Paquin-Proulx, Bianca A N Santos, Karina I Carvalho, Myrthes Toledo-Barros, Ana Karolina Barreto de Oliveira, Cristina M Kokron, Jorge Kalil, Markus Moll, Esper G Kallas, Johan K Sandberg
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75199 (2013)
Common variable immunodeficiency (CVID) is characterized by defective B cell function, impaired antibody production, and increased susceptibility to bacterial infections. Here, we addressed the hypothesis that poor antibody-mediated immune control of
Externí odkaz:
https://doaj.org/article/8f3a7a31903c4af2a1e217cb98cc9d80
Autor:
Michael A Eller, Kim G Blom, Veronica D Gonzalez, Leigh Anne Eller, Prossy Naluyima, Oliver Laeyendecker, Thomas C Quinn, Noah Kiwanuka, David Serwadda, Nelson K Sewankambo, Boonrat Tasseneetrithep, Maria J Wawer, Ronald H Gray, Mary A Marovich, Nelson L Michael, Mark S de Souza, Fred Wabwire-Mangen, Merlin L Robb, Jeffrey R Currier, Johan K Sandberg
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18779 (2011)
HIV-1 disease progression is associated with persistent immune activation. However, the nature of this association is incompletely understood. Here, we investigated immune activation in the CD4 T cell compartment of chronically HIV-1 infected individ
Externí odkaz:
https://doaj.org/article/80b16ccc3560435293e8e3c8573e877f