Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Johan H. van de Sande"'
Publikováno v:
Biochemistry and Cell Biology. 76:391-402
We have correlated the structural perturbations caused by DNA mismatches with the enzymatic data of the interaction of the restriction endonuclease EcoRI with DNA. Oligonucleotides d(CGAGAATTCTCA5GAXAATTCT) (X = G, A, T) and d(CGCGAATTYGCGT4CGCXAATTC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75518fb3d1834f33f9ec9ac388b145e7
https://doi.org/10.1139/o98-031
https://doi.org/10.1139/o98-031
Autor:
Markus W. Gerrnann, Richard T. Pon, James M. Aramini, Johan H. van de Sande, Bernd W. Kalisch
Publikováno v:
Nucleosides and Nucleotides. 16:1481-1485
Oligodeoxynucleotides that possess alpha anomeric nucleotides and polarity reversals show promise for application in the area of antisense therapy. Here we provide a survey of the spectroscopic, thermodynamic, and enzymatic techniques used in our lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb15caf1da99ea1223d4e580e55c86b
https://doi.org/10.1080/07328319708006211
https://doi.org/10.1080/07328319708006211
Publikováno v:
Annals of the New York Academy of Sciences. 726:309-311
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47591d94377429a2a1501fc070a55835
https://doi.org/10.1111/j.1749-6632.1994.tb52835.x
https://doi.org/10.1111/j.1749-6632.1994.tb52835.x
Publikováno v:
Antisensenucleic acid drug development. 8(2)
Human papillomavirus (HPV) type 16 E6 and E7 inactivate the tumor suppressors p53 and pRB, respectively. Both viral oncoproteins play important roles in maintaining the transformed phenotype of cells. In this study, we examine the effects of antisens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427effc4229e71e342e25cecd33a9569
https://pubmed.ncbi.nlm.nih.gov/9593047
https://pubmed.ncbi.nlm.nih.gov/9593047
Publikováno v:
ACS Symposium Series ISBN: 9780841235410
Molecular Modeling of Nucleic Acids
Molecular Modeling of Nucleic Acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83ecaed0195aad46225ed548212d42ee
https://doi.org/10.1021/bk-1998-0682.ch006
https://doi.org/10.1021/bk-1998-0682.ch006
Autor:
Umesh Varshney, Johan H. van de Sande
Publikováno v:
Biochemistry. 30(16)
Uracil DNA glycosylase excises uracil residues from DNA that can arise as a result of deamination of cytosine or incorporation of dUMP residues by DNA polymerase. We have carried out a detailed study to define the specificities and the kinetic parame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7953c770200de401cbd7bde7bb27ef77
https://pubmed.ncbi.nlm.nih.gov/2018771
https://pubmed.ncbi.nlm.nih.gov/2018771
Publikováno v:
Nucleic acids research. 18(6)
We have investigated loop-induced structural perturbation of the stem structure in hairpins d(GAATTCXnGAATTC) (X = A, T and n = 3, 4, 5 and 6) that contain an EcoRI restriction site in close proximity to the hairpin loop. Oligonucleotides containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f71999eb63458ea7a85f9e5f566dfa9
https://pubmed.ncbi.nlm.nih.gov/2326190
https://pubmed.ncbi.nlm.nih.gov/2326190
Publikováno v:
Nucleic Acids Research. 6:1881-1894
The poly(dA) dependent T4 polynucleotide ligase catalyzed polymerization of oligodeoxythymidylates is dependent upon duplex stability. The antibiotics ethidium bromide, netropsin and Hoechst 33258 stabilize the duplex poly(dA) . P(dT)n (n = 6-10) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48704d65f85319ccfaa463049f4e17c5
https://doi.org/10.1093/nar/6.5.1881
https://doi.org/10.1093/nar/6.5.1881
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 5:895-912
pBR322-derived plasmids have been constructed carrying d(GTAC)n.d(GTAC)n inserts of different lengths, in order to investigate the effect of insert size on cruciform extrusion and/or the B-Z transition. Plasmids with n ranging from 4 to 12 are hypers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ca9204a60e6f88325f5b249b64e2ac
https://doi.org/10.1080/07391102.1988.10506433
https://doi.org/10.1080/07391102.1988.10506433
Publikováno v:
Canadian Journal of Chemistry. 46:25-34
The reaction between olefins, N-chloroacetamide or 1,3-dibromo-5,5-dimethylhydantoin, and hydrogen peroxide affords β-halohydroperoxides in good yields. These compounds react extremely rapidly in basic solution to give products which depend upon the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2deb49cbf277a1db79b7beac11e2b0ae
https://doi.org/10.1139/v68-005
https://doi.org/10.1139/v68-005