Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Johan H van Es"'
Autor:
Chuntao Zhao, Yaqi Deng, Lei Liu, Kun Yu, Liguo Zhang, Haibo Wang, Xuelian He, Jincheng Wang, Changqing Lu, Laiman N Wu, Qinjie Weng, Meng Mao, Jianrong Li, Johan H van Es, Mei Xin, Lee Parry, Steven A Goldman, Hans Clevers, Q. Richard Lu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Wnt/β-catenin signaling regulates oligodendrocyte (OL) development. Here the authors show that Tcf7l2, a β-catenin transcriptional partner,sequentially interacts with stage-specific partners to coordinate the transitions of differentiation initiati
Externí odkaz:
https://doaj.org/article/1f0426bb84984cb2bac173cddf0948c3
Autor:
Jinhua Lu, Shuang Zhang, Haruo Nakano, David G Simmons, Shumin Wang, Shuangbo Kong, Qiang Wang, Lianju Shen, Zhaowei Tu, Weixiang Wang, Bingyan Wang, Hongmei Wang, Yanling Wang, Johan H van Es, Hans Clevers, Gustavo Leone, James C Cross, Haibin Wang
Publikováno v:
PLoS Biology, Vol 11, Iss 4, p e1001536 (2013)
Chorioallantoic branching morphogenesis is a key milestone during placental development, creating the large surface area for nutrient and gas exchange, and is therefore critical for the success of term pregnancy. Several Wnt pathway molecules have be
Externí odkaz:
https://doaj.org/article/54c9750bf076432391b07bfdb0ca5122
Autor:
Reinoud E A de Groot, Henner F Farin, Marie Macůrková, Johan H van Es, Hans C Clevers, Hendrik C Korswagen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76971 (2013)
In C. elegans and Drosophila, retromer mediated retrograde transport of Wntless (Wls) from endosomes to the trans-Golgi network (TGN) is required for Wnt secretion. When this retrograde transport pathway is blocked, Wls is missorted to lysosomes and
Externí odkaz:
https://doaj.org/article/c2367ee7cf7449d5af8ef4a530e23350
Autor:
Marc Sylva, Vivian S W Li, Anita A A Buffing, Johan H van Es, Maaike van den Born, Saskia van der Velden, Quinn Gunst, Jan Harm Koolstra, Antoon F M Moorman, Hans Clevers, Maurice J B van den Hoff
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22616 (2011)
Follistatin-like 1 (Fstl1) is a secreted protein of the BMP inhibitor class. During development, expression of Fstl1 is already found in cleavage stage embryos and becomes gradually restricted to mesenchymal elements of most organs during subsequent
Externí odkaz:
https://doaj.org/article/552fb8f457b84cfb83116b626692021b
Autor:
Hans Clevers, Alexander van Oudenaarden, Peter J. Peters, David A. Tuveson, Geert J.P.L. Kops, Ruben van Boxtel, Onno Kranenburg, Priya Sridevi, Nino Iakobachvili, Antoni P.A. Hendrickx, Maurice M.J.M. Zandvliet, Judith Vivié, Mauro J. Muraro, Rurika Oka, Richard H. van Jaarsveld, Gui-Wei He, Veerle Geurts, Johan H. van Es, Harry Begthel, Jeroen Korving, Emma J. de Ruiter, Remco de Bree, Lot A. Devriese, Stefan M. Willems, Kadi Lõhmussaar, Sacha Spelier, Sigrid Kolders, Else Driehuis
Movie S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0841e5cc268c6b6638bd8b10df5c249
https://doi.org/10.1158/2159-8290.22536523
https://doi.org/10.1158/2159-8290.22536523
Autor:
Hans Clevers, Alexander van Oudenaarden, Peter J. Peters, David A. Tuveson, Geert J.P.L. Kops, Ruben van Boxtel, Onno Kranenburg, Priya Sridevi, Nino Iakobachvili, Antoni P.A. Hendrickx, Maurice M.J.M. Zandvliet, Judith Vivié, Mauro J. Muraro, Rurika Oka, Richard H. van Jaarsveld, Gui-Wei He, Veerle Geurts, Johan H. van Es, Harry Begthel, Jeroen Korving, Emma J. de Ruiter, Remco de Bree, Lot A. Devriese, Stefan M. Willems, Kadi Lõhmussaar, Sacha Spelier, Sigrid Kolders, Else Driehuis
Previous studies have described that tumor organoids can capture the diversity of defined human carcinoma types. Here, we describe conditions for long-term culture of human mucosal organoids. Using this protocol, a panel of 31 head and neck squamous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e4c06e92aae2c945d53df37939ee42
https://doi.org/10.1158/2159-8290.c.6548158.v1
https://doi.org/10.1158/2159-8290.c.6548158.v1
Autor:
Hans Clevers, Alexander van Oudenaarden, Peter J. Peters, David A. Tuveson, Geert J.P.L. Kops, Ruben van Boxtel, Onno Kranenburg, Priya Sridevi, Nino Iakobachvili, Antoni P.A. Hendrickx, Maurice M.J.M. Zandvliet, Judith Vivié, Mauro J. Muraro, Rurika Oka, Richard H. van Jaarsveld, Gui-Wei He, Veerle Geurts, Johan H. van Es, Harry Begthel, Jeroen Korving, Emma J. de Ruiter, Remco de Bree, Lot A. Devriese, Stefan M. Willems, Kadi Lõhmussaar, Sacha Spelier, Sigrid Kolders, Else Driehuis
Supplementary Figures including legends, Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394d1f1adbede503e7e8e1180ac1bfbe
https://doi.org/10.1158/2159-8290.22536505.v1
https://doi.org/10.1158/2159-8290.22536505.v1
Publikováno v:
Yamada's Textbook of Gastroenterology. :31-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25ce9fe22ee0b877c6b30bff50647214
https://doi.org/10.1002/9781119600206.ch2
https://doi.org/10.1002/9781119600206.ch2
Autor:
Harry Begthel, Johan H. van Es, Hans Clevers, Oded Kopper, Celien P.H. Vreuls, Kadi Lõhmussaar, Jeroen Korving
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
High-grade serous ovarian cancer (HG-SOC)—often referred to as a “silent killer”—is the most lethal gynecological malignancy. The fallopian tube (murine oviduct) and ovarian surface epithelium (OSE) are considered the main candidate tissues o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a7f1303fbb141a1656f3962916050f
https://doaj.org/article/b561dc387d334f75b89e8a94ccc8b593
https://doaj.org/article/b561dc387d334f75b89e8a94ccc8b593
Autor:
Nick Barker, Maarten B. Rookmaaker, Pekka Kujala, Annie Ng, Marc Leushacke, Hugo Snippert, Marc van de Wetering, Shawna Tan, Johan H. Van Es, Meritxell Huch, Richard Poulsom, Marianne C. Verhaar, Peter J. Peters, Hans Clevers
Publikováno v:
Cell Reports, Vol 2, Iss 3, Pp 540-552 (2012)
Multipotent stem cells and their lineage-restricted progeny drive nephron formation within the developing kidney. Here, we document expression of the adult stem cell marker Lgr5 in the developing kidney and assess the stem/progenitor identity of Lgr5
Externí odkaz:
https://doaj.org/article/080bb29615104b7eb96138775e7cda62