Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Johan H Faber"'
Autor:
George Nicholson, Mattias Rantalainen, Anthony D Maher, Jia V Li, Daniel Malmodin, Kourosh R Ahmadi, Johan H Faber, Ingileif B Hallgrímsdóttir, Amy Barrett, Henrik Toft, Maria Krestyaninova, Juris Viksna, Sudeshna Guha Neogi, Marc‐Emmanuel Dumas, Ugis Sarkans, The MolPAGE Consortium, Bernard W Silverman, Peter Donnelly, Jeremy K Nicholson, Maxine Allen, Krina T Zondervan, John C Lindon, Tim D Spector, Mark I McCarthy, Elaine Holmes, Dorrit Baunsgaard, Chris C Holmes
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-12 (2011)
Abstract 1H Nuclear Magnetic Resonance spectroscopy (1H NMR) is increasingly used to measure metabolite concentrations in sets of biological samples for top‐down systems biology and molecular epidemiology. For such purposes, knowledge of the source
Externí odkaz:
https://doaj.org/article/f335db8f4a53437692b5541fc67ede7b
Autor:
Anna L Gloyn, Johan H Faber, Daniel Malmodin, Gaya Thanabalasingham, Francis Lam, Per Magne Ueland, Mark I McCarthy, Katharine R Owen, Dorrit Baunsgaard
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40962 (2012)
It is important to identify patients with Maturity-onset diabetes of the young (MODY) as a molecular diagnosis determines both treatment and prognosis. Genetic testing is currently expensive and many patients are therefore not assessed and are miscla
Externí odkaz:
https://doaj.org/article/09ce015143b74357987447eb33ceab0a
Autor:
George Nicholson, Mattias Rantalainen, Jia V Li, Anthony D Maher, Daniel Malmodin, Kourosh R Ahmadi, Johan H Faber, Amy Barrett, Josine L Min, N William Rayner, Henrik Toft, Maria Krestyaninova, Juris Viksna, Sudeshna Guha Neogi, Marc-Emmanuel Dumas, Ugis Sarkans, MolPAGE Consortium, Peter Donnelly, Thomas Illig, Jerzy Adamski, Karsten Suhre, Maxine Allen, Krina T Zondervan, Tim D Spector, Jeremy K Nicholson, John C Lindon, Dorrit Baunsgaard, Elaine Holmes, Mark I McCarthy, Chris C Holmes
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002270 (2011)
We have performed a metabolite quantitative trait locus (mQTL) study of the (1)H nuclear magnetic resonance spectroscopy ((1)H NMR) metabolome in humans, building on recent targeted knowledge of genetic drivers of metabolic regulation. Urine and plas
Externí odkaz:
https://doaj.org/article/1c14554088b5407e99f8d8f2207e1483
Autor:
Gert Bolt, Jens Jacob Hansen, Ernst Broberg Hansen, Haleh Ahmadian, Lars Sejergaard, Lars Thim, Johan Karlsson, Johan H. Faber
Publikováno v:
Blood Coagulation & Fibrinolysis
Turoctocog alfa (NovoEight) is a third-generation recombinant factor VIII (rFVIII) with a truncated B-domain that is manufactured in Chinese hamster ovary cells. No human or animal-derived materials are used in the process. The aim of this study is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e745c208bf48b09dc7eb1b9ceb0b213b
https://doi.org/10.1097/mbc.0000000000000477
https://doi.org/10.1097/mbc.0000000000000477
Autor:
Ole Hvilsted Olsen, Y. Zenmei Ohkubo, Emad Tajkhorshid, Günther H.J. Peters, Jesper J. Madsen, Johan H. Faber
Publikováno v:
Biochemistry. 54:6123-6131
A recently developed membrane-mimetic model was applied to study membrane interaction and binding of the two anchoring C2-like discoidin domains of human coagulation factor VIIIa (FVIIIa), the C1 and C2 domains. Both individual domains, FVIII C1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99782eed7733fa5ef9ae7ff49942e6b5
https://doi.org/10.1021/acs.biochem.5b00417
https://doi.org/10.1021/acs.biochem.5b00417
Autor:
Jan Voorberg, Esther Bloem, Aleksandra Wroblewska, Koen Mertens, Maartje van den Biggelaar, Marianne Kjalke, Henning R. Stennicke, Alexander B. Meijer, Johan H. Faber
Publikováno v:
Journal of biological chemistry, 288(41), 29670-29679. American Society for Biochemistry and Molecular Biology Inc.
The C1 domain of factor VIII (FVIII) has been implicated in binding to multiple constituents, including phospholipids, von Willebrand factor, and low-density lipoprotein receptor-related protein (LRP). We have previously described a human monoclonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705da9f86e194fd2b7ed8c3683d37669
https://doi.org/10.1074/jbc.m113.473116
https://doi.org/10.1074/jbc.m113.473116
Autor:
Mette Dahl Andersen, Johan H. Faber
Publikováno v:
International Journal of Mass Spectrometry. 302:139-148
Activated Factor XIII is a 83 kDa transglutaminase crucial in the final steps of blood coagulation. FXIII can be activated both via a proteolytic pathway and a non-proteolytic pathway. Activation in plasma takes place by a thrombin catalyzed cleavage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::134a23b1852760f0226d561861a2eaf5
https://doi.org/10.1016/j.ijms.2010.09.010
https://doi.org/10.1016/j.ijms.2010.09.010
Autor:
Martin Horstmann, Cornelius Faber, Kai F. Schwedhelm, Johan H. Faber, Gerhard Bringmann, Michael Büchner, Yana Reichert
Publikováno v:
The Open Spectroscopy Journal. 2:10-18
Complex formation between the antimalarial drug chloroquine and its presumed target ferriprotoporphyrin IX in three different solutions (pH 6.5, pH 9, and in a water methanol mixture) is characterized by nuclear magnetic resonance, UV spectroscopy, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44c7d2b85ae24e42bd0f5d5de0b220b0
https://doi.org/10.2174/1874383800802010010
https://doi.org/10.2174/1874383800802010010
Autor:
Michael Dreyer, Reto Brun, Gerhard Bringmann, Joanna Spuziak, Tanja Gulder, Inga Kajahn, Virima Mudogo, Günther Heubl, Johan H. Faber
Publikováno v:
Phytochemistry. 69:1065-1075
From the roots of a recently discovered Ancistrocladus taxon, with close affinities to Ancistrocladus congolensis regarding molecular ITS sequence data, six naphthylisoquinoline alkaloids, 5'-O-demethylhamatine (2), 5'-O-demethylhamatinine (3), 6-O-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903f16b7bdce9cdca34018696bf46cb3
https://doi.org/10.1016/j.phytochem.2007.10.027
https://doi.org/10.1016/j.phytochem.2007.10.027
Autor:
Dorrit Baunsgaard, Johan H. Faber, Jeremy K. Nicholson, Henrik Toft, Elaine Holmes, Anthony D. Maher, Daniel Malmodin, Marc E. Dumas, Derek J. Crockford
Publikováno v:
Scopus-Elsevier
Metabonomics has been defined as "quantitative measurement of the dynamic multiparametric metabolic response of living systems to pathophysiological stimuli or genetic modification" and can provide information on disease processes, drug toxicity, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79bfa14f2bd51c270495e7ebd0ec291
https://doi.org/10.1177/193229680700100413
https://doi.org/10.1177/193229680700100413