Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Johan Ericson"'
Autor:
Zhanna Alekseenko, José M. Dias, Andrew F. Adler, Mariya Kozhevnikova, Josina Anna van Lunteren, Sara Nolbrant, Ashwini Jeggari, Svitlana Vasylovska, Takashi Yoshitake, Jan Kehr, Marie Carlén, Andrey Alexeyenko, Malin Parmar, Johan Ericson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Stem cell based replacement therapies could provide a treatment for Parkinson’s disease. Here the authors outline a retinoic acid-based approach for robust derivation of dopamine neurons from stem cells that restore motor deficits in parkinsonian r
Externí odkaz:
https://doaj.org/article/c1584053ca2d444f8ae84087bed8e232
Autor:
José M. Dias, Shirin Ilkhanizadeh, Esra Karaca, Joshua K. Duckworth, Vanessa Lundin, Michael G. Rosenfeld, Johan Ericson, Ola Hermanson, Ana I. Teixeira
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 665-670 (2014)
Bone morphogenetic proteins (BMPs) secreted by the dorsal neural tube and overlying ectoderm are key signals for the specification of the roof plate and dorsal interneuron populations. However, the signals that confer nonneurogenic character to the r
Externí odkaz:
https://doaj.org/article/eb74307279ea4cefb609b8cb11cd77b8
Autor:
Lia Panman, Maria Papathanou, Ariadna Laguna, Tony Oosterveen, Nikolaos Volakakis, Dario Acampora, Idha Kurtsdotter, Takashi Yoshitake, Jan Kehr, Eliza Joodmardi, Jonas Muhr, Antonio Simeone, Johan Ericson, Thomas Perlmann
Publikováno v:
Cell Reports, Vol 8, Iss 4, Pp 1018-1025 (2014)
Distinct midbrain dopamine (mDA) neuron subtypes are found in the substantia nigra pars compacta (SNc) and the ventral tegmental area (VTA), but it is mainly SNc neurons that degenerate in Parkinson’s disease. Interest in how mDA neurons develop ha
Externí odkaz:
https://doaj.org/article/ba6aa9efcd9841008ff6c5b6521d0229
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124408 (2015)
Cranial motor nerves in vertebrates are comprised of the three principal subtypes of branchial, visceral, and somatic motor neurons, which develop in typical patterns along the anteroposterior and dorsoventral axes of hindbrain. Here we demonstrate t
Externí odkaz:
https://doaj.org/article/c6b22b2d4afa4f2da41b5cc46b7ff437
Autor:
Mariya Kozhevnikova, Marcelo Boareto, Ashwini Jeggari, José M. Dias, Zhanna Alekseenko, Andrey Alexeyenko, Hui Wang, Michael P. Matise, Jannik Vollmer, Johan Ericson, Dagmar Iber
Publikováno v:
Science Advances
Science Advances, 6 (38)
Science Advances, 6 (38)
How time is measured by neural stem cells during temporal neurogenesis has remained unresolved. By combining experiments and computational modeling, we define a Shh/Gli-driven three-node timer underlying the sequential generation of motor neurons (MN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b815ff000339e8ea28ca6836305f3fc5
Autor:
Iurii Petrov, José M. Dias, Zhanna Alekseenko, Ashwini Jeggari, Johan Ericson, Andrey Alexeyenko
Publikováno v:
Nucleic Acids Research
The new web resource EviNet provides an easily run interface to network enrichment analysis for exploration of novel, experimentally defined gene sets. The major advantages of this analysis are (i) applicability to any genes found in the global netwo
Sequentially acting SOX proteins orchestrate astrocyte‐ and oligodendrocyte‐specific gene expression
Autor:
Åsa K. Björklund, Susanne Klum, Zhanna Alekseenko, Daniel W. Hagey, Jonas Muhr, Maria Bergsland, Johan Ericson, Cecile Zaouter
Publikováno v:
EMBO reports. 19
SOX transcription factors have important roles during astrocyte and oligodendrocyte development, but how glial genes are specified and activated in a sub-lineage-specific fashion remains unknown. Here, we define glial-specific gene expression in the
Publikováno v:
Neuron. 84(5):927-939
SummaryHow the sequential specification of neurons and progressive loss of potency associated with aging neural progenitors are regulated in vertebrate brain development is poorly understood. By examining a temporal differentiation lineage in the hin
Autor:
Raoul Kuiper, Cornelius Trünkle, Åsa Bergström, Marco Gerling, Rune Toftgård, Maria A. Hoelzl, José M. Dias, Karin Heby-Henricson, Johan Ericson, Stephan Teglund
Publikováno v:
Developmental biology. 429(1)
Suppressor of Fused (SUFU) is an essential negative regulator of the Hedgehog (HH) pathway and involved in GLI transcription factor regulation. Due to early embryonic lethality of Sufu-/- mice, investigations of SUFU's role later in development are l
Autor:
Joshua K. Duckworth, Shirin Ilkhanizadeh, Johan Ericson, Esra Karaca, Ana I. Teixeira, Ola Hermanson, José M. Dias, Michael G. Rosenfeld, Vanessa Lundin
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 665-670 (2014)
SummaryBone morphogenetic proteins (BMPs) secreted by the dorsal neural tube and overlying ectoderm are key signals for the specification of the roof plate and dorsal interneuron populations. However, the signals that confer nonneurogenic character t