Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Johan E. van Lier"'
Autor:
Ana F. Amendoeira, André Luz, Ruben Valente, Catarina Roma-Rodrigues, Hasrat Ali, Johan E. van Lier, Fernanda Marques, Pedro V. Baptista, Alexandra R. Fernandes
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3600
Volume 24
Issue 4
Pages: 3600
Estradiol-BODIPY linked via an 8-carbon spacer chain and 19-nortestosterone- and testosterone-BODIPY linked via an ethynyl spacer group were evaluated for cell uptake in the breast cancer cell lines MCF-7 and MDA-MB-231 and prostate cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39e33ebd02eacb993772bdf7632dacd
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 26:147-161
The chemistry of gem-dibromovinyl derivatives has undergone a renaissance through the application of palladium catalysis and has been applied to pyrrole substituted gem-dibromovinyl BODIPY. gem-Dibromovinyl BODIPYs (substituted at either the [Formula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cdccaeba8fcbdc7711165a999e52f86
https://doi.org/10.1142/s1088424621501182
https://doi.org/10.1142/s1088424621501182
Publikováno v:
European Journal of Organic Chemistry. 2021:3123-3132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e4e3cee88a18bdc52147e7afbedc31
https://doi.org/10.1002/ejoc.202100133
https://doi.org/10.1002/ejoc.202100133
Autor:
Hasrat, Ali, Johan E, van Lier
Publikováno v:
Steroids. 187:109092
The systematic X-ray structure analyses of the primary cholesterol sidechain autoxidation products cholesterol 25- and 20β(S)-hydroperoxide are presented and compared to cholesterol and 25-hydroxycholesterol. Intermolecular interactions in crystal s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc7b94bf81ec4d471a8e7a56098b4cc
https://doi.org/10.1016/j.steroids.2022.109092
https://doi.org/10.1016/j.steroids.2022.109092
Autor:
Johan E. van Lier
Publikováno v:
Journal of Medicinal Chemistry. 63:6474-6476
Cytochrome P450 46A1 (CYP46A1) or cholesterol-24-hydroxylase is responsible for cholesterol metabolism and homeostasis in the human brain. More recently its activity has been linked to brain function and disease. The anti-HIV drug efavirenz activates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9578545a5557012b112a45d3fdcbeda5
https://doi.org/10.1021/acs.jmedchem.9b01947
https://doi.org/10.1021/acs.jmedchem.9b01947
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 23:781-796
Fluorescence and SPECT/PET imaging are powerful tools currently in use by the scientific community and receiving a great attention for the development of dual-modality imaging agents. BODIPYs are among the most promising candidates to be used for suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d87a411319f623e6999943e1401cf14
https://doi.org/10.1142/s1088424619300155
https://doi.org/10.1142/s1088424619300155
Autor:
Johan E. van Lier, Benoit Paquette
Publikováno v:
Photodynamic Therapy ISBN: 9781003066897
Photodynamic Therapy
Photodynamic Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d70089dc40a9753c1f5bd70f0db8fa4
https://doi.org/10.1201/9781003066897-11
https://doi.org/10.1201/9781003066897-11
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 21:701-730
This review focuses on progress in the development of different approaches to the design of steroid ([Formula: see text] estrogens, androgens, cholesterol) conjugates with coordination assemblies of metalloporphyrins, phthalocyanines and related comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8715233d284667ae9fa3a7e10801c37
https://doi.org/10.1142/s108842461730004x
https://doi.org/10.1142/s108842461730004x
Autor:
Michel Paquette, Helena Senta, Eric Turcotte, Brigitte Guérin, René Ouellet, Serge Phoenix, Roger Lecomte, Eric Lavallee, Johan E. van Lier
Publikováno v:
Journal of Nuclear Medicine. 59:197-203
After encouraging preclinical and human dosimetry results for the novel estrogen receptor (ER) PET radiotracer 4-fluoro-11β-methoxy-16α-18F-fluoroestradiol (18F-4FMFES), a phase II clinical trial was initiated to compare the PET imaging diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cd14e0f5bdf185711f8835b8c8de1c5
https://doi.org/10.2967/jnumed.117.194654
https://doi.org/10.2967/jnumed.117.194654