Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Johan E. Wallin"'
Autor:
Michael Chisamore, Jeffrey Yachnin, Ana Carneiro, Linda Mårtensson, Ingrid Teige, Björn Frendeus, Petra Holmkvist, Andres McAllister, Marie Borggren, Ingrid Karlsson, Mark Cragg, Lars Ny, Zsuzsanna Pápai, Kristoffer Staahl Rohrberg, Kirstie Cleary, Jan Anders Nilsson, Sean Lim, Johan E Wallin, Istvan Lang, Harriet Walter, Rikke H Lovendahl Eefsen, Edvard Abel, Robert Oldham, Susanne Gertsson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/dd0363883565431e9df3d3d5fc0b3659
Autor:
Monika Semmrich, Linda Mårtensson, Ingrid Teige, Björn Frendeus, Mathilda Kovacek, Petra Holmkvist, Carolin Svensson, Therese Blidberg, Andres McAllister, Marie Borggren, Ingrid Karlsson, Mark Cragg, Mimoza Bodén, Kirstie Cleary, Osman Dadas, Benjamin Duell, Jan Anders Nilsson, Stephen Beers, Sean Lim, Johan E Wallin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e0e8b870548644bdb65e3e93dec0f252
Publikováno v:
Wear. 301:109-115
In this work wear of cemented carbide rock drill inserts is evaluated by using a rotating rock cylinder as counter surface. The influence on wear rate and degradation mechanisms from varying dry and wet conditions, cemented carbide grade, abrasive pa
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 106:234-242
One of the most employed approaches to reduce severe neutropenia following anticancer drug regimens is to reduce the consecutive dose in fixed steps, commonly by 25%. Another approach has been to use pharmacokinetic (PK) sampling to tailor dosing, bu
Publikováno v:
Clinical Cancer Research. 12:5481-5490
Purpose: Cancer chemotherapy, although based on body surface area, often causes unpredictable myelosuppression, especially severe neutropenia. The aim of this study was to evaluate qualitatively and quantitatively the influence of patient-specific ch
Autor:
Mats O. Karlsson, Christine E. Staatz, Martin Bergstrand, Henryk E Wilczek, Johan E. Wallin, Per S. Nydert
Publikováno v:
Therapeutic drug monitoring. 33(6)
BACKGROUND: Tacrolimus is an immunosuppressant with a narrow therapeutic window, with considerable pharmacokinetic variability. Getting sufficient concentrations in pediatric liver transplantation is imperative, but it has proven difficult in the imm
Publikováno v:
The AAPS journal. 13(2)
Informative diagnostic tools are vital to the development of useful mixed-effects models. The Visual Predictive Check (VPC) is a popular tool for evaluating the performance of population PK and PKPD models. Ideally, a VPC will diagnose both the fixed
Autor:
Henrik Lindman, Marie Sandström, Emma K. Hansson, Johan E. Wallin, Lena E. Friberg, Mats O. Karlsson
A previously developed semi-physiological model of chemotherapy-induced myelosuppression has shown consistent system-related parameter and inter-individual variability (IIV) estimates across drugs. A requirement for dose individualization to be usefu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01721242824a8cd4a6370e2435b93843
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-100507
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-100507
Publikováno v:
Therapeutic drug monitoring. 31(4)
The population pharmacokinetics of tacrolimus was described in 22 pediatric hematopoietic stem cell transplant recipients, and a model-based dosage adjustment tool that may assist with therapy in new patients was developed. Patients received tacrolim
Publikováno v:
Computer methods and programs in biomedicine. 93(3)
Chemotherapy dosing in anticancer treatment is a balancing act between achieving concentrations that are effective towards the malignancy and that result in acceptable side-effects. Neutropenia is one major side-effect of many antitumor agents, and i