Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Johan E. Deecke"'
Autor:
Mark A. T. Blaskovich, Karl A. Hansford, Yujing Gong, Mark S. Butler, Craig Muldoon, Johnny X. Huang, Soumya Ramu, Alberto B. Silva, Mu Cheng, Angela M. Kavanagh, Zyta Ziora, Rajaratnam Premraj, Fredrik Lindahl, Tanya A. Bradford, June C. Lee, Tomislav Karoli, Ruby Pelingon, David J. Edwards, Maite Amado, Alysha G. Elliott, Wanida Phetsang, Noor Huda Daud, Johan E. Deecke, Hanna E. Sidjabat, Sefetogi Ramaologa, Johannes Zuegg, Jason R. Betley, Andrew P. G. Beevers, Richard A. G. Smith, Jason A. Roberts, David L. Paterson, Matthew A. Cooper
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The antibiotic vancomycin inhibits bacterial cell wall synthesis by binding to a membrane-associated precursor. Here, Blaskovich et al. synthesize vancomycin derivatives containing lipophilic peptide moieties that enhance membrane affinity and in viv
Externí odkaz:
https://doaj.org/article/5939bc54d4b347d7b1b16946d6d5c490
Autor:
Hanna E. Sidjabat, David Edwards, Andrew P. G. Beevers, Ruby Pelingon, Zyta M. Ziora, Karl A. Hansford, Fredrik Lindahl, Noor Huda Daud, Sefetogi Ramaologa, Tanya A. Bradford, Jason A. Roberts, Mark E. Cooper, Angela M. Kavanagh, June C. Lee, Yujing Gong, David L. Paterson, Soumya Ramu, Maite Amado, Wanida Phetsang, Tomislav Karoli, Johannes Zuegg, Alberto B. Silva, Johnny X. Huang, Alysha G. Elliott, Mark S. Butler, Richard A. G. Smith, Rajaratnam Premraj, Craig Muldoon, Mark A. T. Blaskovich, Mu Cheng, Johan E. Deecke, Jason Betley
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications
The public health threat posed by a looming ‘post-antibiotic’ era necessitates new approaches to antibiotic discovery. Drug development has typically avoided exploitation of membrane-binding properties, in contrast to nature’s control of biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7366661a67b35b8ed35840cfd588645
https://doi.org/10.1038/s41467-017-02123-w
https://doi.org/10.1038/s41467-017-02123-w