Spontaneous Closure of the Ductus Arteriosus in Preterm Infants: A Systematic Review

Autor: Johan C. A. de Klerk, Aline G. J. Engbers, Floor van Beek, Robert B. Flint, Irwin K. M. Reiss, Swantje Völler, Sinno H. P. Simons

Publikováno v: Frontiers in Pediatrics, Vol 8 (2020)

The optimal management strategy for patent ductus arteriosus in preterm infants remains a topic of debate. Available evidence for a treatment strategy might be biased by the delayed spontaneous closure of the ductus arteriosus in preterm infants, whi

Externí odkaz: https://doaj.org/article/f85004a4f15d4332ba261ee1c338e432

Enantiomer specific pharmacokinetics of ibuprofen in preterm neonates with patent ductus arteriosus

Autor: Johan C. A. de Klerk, Pieter L.J. Degraeuwe, Siska Croubels, Sinno H.P. Simons, Karel Allegaert, Swantje Völler, Kian D. Liem, Joske Millecam, Peter Andriessen, Aline G.J. Engbers, Catherijne A. J. Knibbe, Irwin K M Reiss, Robert B. Flint

Publikováno v: British Journal of Clinical Pharmacology, 86, 10, pp. 2028-2039
British Journal of Clinical Pharmacology, 86(10), 2028-2039. Wiley-Blackwell Publishing Ltd
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, 86, 2028-2039
British Journal of Clinical Pharmacology, 86(10), 2028-2039. Wiley
British Journal of Clinical Pharmacology, 86(10), 2028-2039. Wiley-Blackwell
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

AIMS: Racemic ibuprofen is widely used for the treatment of preterm neonates with patent ductus arteriosus. Currently used bodyweight-based dosing guidelines are based on total ibuprofen, while only the S-enantiomer of ibuprofen is pharmacologically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743f1d8b1372607ba66011e4dea8034b
https://hdl.handle.net/2066/229867

Limited effects of intravenous paracetamol on patent ductus arteriosus in very low birth weight infants with contraindications for ibuprofen or after ibuprofen failure

Autor: Ingrid M. van Beynum, Irwin K M Reiss, Monique van Dijk, Johan C. A. de Klerk, Daniëlla W. E. Roofthooft, John N. van den Anker, Sinno H.P. Simons, Dick Tibboel

Publikováno v: European Journal of Pediatrics, 174(11), 1433-1440. Springer-Verlag
European Journal of Pediatrics

Finding the optimal pharmacological treatment of a patent ductus arteriosus (PDA) in preterm neonates remains challenging. There is a growing interest in paracetamol as a new drug for PDA closure. In this prospective observational cohort study, we ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e9730ea15b4344f51ff1192154d0e0