Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Johan Bjorkegren"'
Publikováno v:
Bioinformatics and Biology Insights, Vol 2008, Iss 2, Pp 307-316 (2008)
Externí odkaz:
https://doaj.org/article/583d157cdfad42b5a68934eea0bbb765
Autor:
John-Bjarne Hansen, José A. Fernández, Ann-Trude With Notø, Hiroshi Deguchi, Johan Björkegren, Ellisiv B. Mathiesen
Publikováno v:
Journal of Lipids, Vol 2011 (2011)
Background. Experimental studies in animals suggest that apolipoprotein (apo) C-I is an important regulator of triglycerides in fasting and postprandial conditions and associated with carotid atherosclerosis. Methods. A cross-sectional study was cond
Externí odkaz:
https://doaj.org/article/76ada575b8924b97903a005e8ddb48e1
Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes.
Autor:
Josefin Skogsberg, Jesper Lundström, Alexander Kovacs, Roland Nilsson, Peri Noori, Shohreh Maleki, Marina Köhler, Anders Hamsten, Jesper Tegnér, Johan Björkegren
Publikováno v:
PLoS Genetics, Vol 4, Iss 3, p e1000036 (2008)
Despite the well-documented effects of plasma lipid lowering regimes halting atherosclerosis lesion development and reducing morbidity and mortality of coronary artery disease and stroke, the transcriptional response in the atherosclerotic lesion med
Externí odkaz:
https://doaj.org/article/0628a124023e4368ae1442558fe68a23
Autor:
Chani J Hodonsky, Adam Turner, Nelson Barrientos, Nicolas Lopez, Jason C Kovacic, Johan Bjorkegren, Nicholas Leeper, Clint Miller
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: Atherosclerotic plaque progression to coronary artery disease is the leading cause of death worldwide. The basic pathophysiology of atherosclerosis is well described, but underlying genetic mechanisms of contributing cell types remain inc
Autor:
Doris Wong, Adam Turner, Mohammad Daud Khan, Meredith Palmore, Noah Perry, maniselvan kuppusamy, Matteo Ottolini, Ljubica Matic, Ulf Hedin, Lijiang Ma, Swapnil K Sonkusare, Mete Civelek, Jason C Kovacic, Johan Bjorkegren, Clint L Miller
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Introduction: Coronary artery disease (CAD) is the leading cause of death worldwide with an estimated heritability of ~50%. The most recent genome wide association study (GWAS) for CAD and myocardial infarction (MI) identified over 200 loci. One such
Autor:
Gabriel F Alencar, Ryan Haskins, Vamsidhar M Venkata, Johan Bjorkegren, Stefan Bekiranov, Gary K Owens
Publikováno v:
Circulation. 138
Atherosclerosis is a disease of chronic inflammation and the leading cause of morbidity and mortality worldwide. Despite decades of research, our understanding of the mechanisms regulating plaque stability remains poor. Until recently, smooth muscle
Autor:
Zeyneb Kurt, Jenny Cheng, Rio Barrere-Cain, Caden N McQuillen, Zara Saleem, Neil Hsu, Nuoya Jiang, Calvin Pan, Oscar Franzén, Simon Koplev, Susanna Wang, Johan Björkegren, Aldons J Lusis, Montgomery Blencowe, Xia Yang
Publikováno v:
eLife, Vol 12 (2023)
Mouse models have been used extensively to study human coronary artery disease (CAD) or atherosclerosis and to test therapeutic targets. However, whether mouse and human share similar genetic factors and pathogenic mechanisms of atherosclerosis has n
Externí odkaz:
https://doaj.org/article/e87fc1a00ff440dc9b28b69b90ccd82d
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 2, Pp 267-277 (2007)
Together with computational analysis and modeling, the development of whole-genome measurement technologies holds the potential to fundamentally change research on complex disorders such as coronary artery disease. With these tools, the stage has bee
Externí odkaz:
https://doaj.org/article/25b8566c0a8641c887c72580320a074a
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 7, Pp 1412-1420 (1998)
Triglyceride-rich lipoproteins (TRLs) that are modified during alimentary lipemia and their remnants are indicated to play an important role in the development of atherosclerosis. Although recent studies in transgenic and gene knock-out animal models
Externí odkaz:
https://doaj.org/article/230611cdd9fe47f8a2ddfddac4665052
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 2, Pp 423-436 (1998)
Exaggerated and prolonged postprandial triglyceridemia is a characteristic of patients with precocious coronary heart disease. Although large very low density lipoprotein (VLDL) particles accumulate during alimentary lipemia, the biological propertie
Externí odkaz:
https://doaj.org/article/39264f0420254887abf690514671d38d