Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Johan Bielecki"'
Autor:
Patrick Y. A. Reinke, Robin Schubert, Dominik Oberthür, Marina Galchenkova, Aida Rahmani Mashhour, Sebastian Günther, Anaïs Chretien, Adam Round, Brandon Charles Seychell, Brenna Norton-Baker, Chan Kim, Christina Schmidt, Faisal H. M. Koua, Alexandra Tolstikova, Wiebke Ewert, Gisel Esperanza Peña Murillo, Grant Mills, Henry Kirkwood, Hévila Brognaro, Huijong Han, Jayanath Koliyadu, Joachim Schulz, Johan Bielecki, Julia Lieske, Julia Maracke, Juraj Knoska, Kristina Lorenzen, Lea Brings, Marcin Sikorski, Marco Kloos, Mohammad Vakili, Patrik Vagovic, Philipp Middendorf, Raphael de Wijn, Richard Bean, Romain Letrun, Seonghyun Han, Sven Falke, Tian Geng, Tokushi Sato, Vasundara Srinivasan, Yoonhee Kim, Oleksandr M. Yefanov, Luca Gelisio, Tobias Beck, Andrew S. Doré, Adrian P. Mancuso, Christian Betzel, Saša Bajt, Lars Redecke, Henry N. Chapman, Alke Meents, Dušan Turk, Winfried Hinrichs, Thomas J. Lane
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The main protease (Mpro) of SARS-CoV-2 is critical for viral function and a key drug target. Mpro is only active when reduced; turnover ceases upon oxidation but is restored by re-reduction. This suggests the system has evolved to survive pe
Externí odkaz:
https://doaj.org/article/7a737b71ae764265a7f11a3df650ea0b
Autor:
Safi Rafie-Zinedine, Tej Varma Yenupuri, Lena Worbs, Filipe R. N. C. Maia, Michael Heymann, Joachim Schulz, Johan Bielecki
Publikováno v:
Journal of Synchrotron Radiation, Vol 31, Iss 2, Pp 222-232 (2024)
This work investigates the performance of the electrospray aerosol generator at the European X-ray Free Electron Laser (EuXFEL). This generator is, together with an aerodynamic lens stack that transports the particles into the X-ray interaction vacuu
Externí odkaz:
https://doaj.org/article/4b5778aa6deb424c9cfa837076a66173
Autor:
Tej Varma Yenupuri, Safi Rafie-Zinedine, Lena Worbs, Michael Heymann, Joachim Schulz, Johan Bielecki, Filipe R. N. C. Maia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Imaging the structure and observing the dynamics of isolated proteins using single-particle X-ray diffractive imaging (SPI) is one of the potential applications of X-ray free-electron lasers (XFELs). Currently, SPI experiments on isolated pr
Externí odkaz:
https://doaj.org/article/8b520020752e4fb8a0471624370323ed
Autor:
Gábor Bortel, Miklós Tegze, Marcin Sikorski, Richard Bean, Johan Bielecki, Chan Kim, Jayanath C. P. Koliyadu, Faisal H. M. Koua, Marco Ramilli, Adam Round, Tokushi Sato, Dmitrii Zabelskii, Gyula Faigel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract X-ray Free Electron Lasers (XFEL) are cutting-edge pulsed x-ray sources, whose extraordinary pulse parameters promise to unlock unique applications. Several new methods have been developed at XFELs; however, no methods are known, which allow
Externí odkaz:
https://doaj.org/article/b10571628e4544a9a761b66688f7dcc3
Autor:
Tomas Ekeberg, Dameli Assalauova, Johan Bielecki, Rebecca Boll, Benedikt J. Daurer, Lutz A. Eichacker, Linda E. Franken, Davide E. Galli, Luca Gelisio, Lars Gumprecht, Laura H. Gunn, Janos Hajdu, Robert Hartmann, Dirk Hasse, Alexandr Ignatenko, Jayanath Koliyadu, Olena Kulyk, Ruslan Kurta, Markus Kuster, Wolfgang Lugmayr, Jannik Lübke, Adrian P. Mancuso, Tommaso Mazza, Carl Nettelblad, Yevheniy Ovcharenko, Daniel E. Rivas, Max Rose, Amit K. Samanta, Philipp Schmidt, Egor Sobolev, Nicusor Timneanu, Sergey Usenko, Daniel Westphal, Tamme Wollweber, Lena Worbs, Paul Lourdu Xavier, Hazem Yousef, Kartik Ayyer, Henry N. Chapman, Jonas A. Sellberg, Carolin Seuring, Ivan A. Vartanyants, Jochen Küpper, Michael Meyer, Filipe R. N. C. Maia
Publikováno v:
Light: Science & Applications, Vol 13, Iss 1, Pp 1-11 (2024)
Abstract The idea of using ultrashort X-ray pulses to obtain images of single proteins frozen in time has fascinated and inspired many. It was one of the arguments for building X-ray free-electron lasers. According to theory, the extremely intense pu
Externí odkaz:
https://doaj.org/article/990d0d21eb0d4351888a9b904a55ebd1
Autor:
Patrick E. Konold, Tong You, Johan Bielecki, Joana Valerio, Marco Kloos, Daniel Westphal, Alfredo Bellisario, Tej Varma Yenupuri, August Wollter, Jayanath C. P. Koliyadu, Faisal H.M. Koua, Romain Letrun, Adam Round, Tokushi Sato, Petra Mészáros, Leonardo Monrroy, Jennifer Mutisya, Szabolcs Bódizs, Taru Larkiala, Amke Nimmrich, Roberto Alvarez, Patrick Adams, Richard Bean, Tomas Ekeberg, Richard A. Kirian, Andrew V. Martin, Sebastian Westenhoff, Filipe R. N. C. Maia
Publikováno v:
IUCrJ, Vol 10, Iss 6, Pp 662-670 (2023)
X-ray free-electron lasers (XFELs) can probe chemical and biological reactions as they unfold with unprecedented spatial and temporal resolution. A principal challenge in this pursuit involves the delivery of samples to the X-ray interaction point in
Externí odkaz:
https://doaj.org/article/fa25df8b41a2470ca3b53093fe9cc51e
Autor:
Egor Sobolev, Philipp Schmidt, Janusz Malka, David Hammer, Djelloul Boukhelef, Johannes Möller, Karim Ahmed, Richard Bean, Ivette Jazmín Bermúdez Macías, Johan Bielecki, Ulrike Bösenberg, Cammille Carinan, Fabio Dall’Antonia, Sergey Esenov, Hans Fangohr, Danilo Enoque Ferreira de Lima, Luís Gonçalo Ferreira Maia, Hadi Firoozi, Gero Flucke, Patrick Gessler, Gabriele Giovanetti, Jayanath Koliyadu, Anders Madsen, Thomas Michelat, Michael Schuh, Marcin Sikorski, Alessandro Silenzi, Jolanta Sztuk-Dambietz, Monica Turcato, Oleksii Turkot, James Wrigley, Steve Aplin, Steffen Hauf, Krzysztof Wrona, Luca Gelisio
Publikováno v:
Frontiers in Physics, Vol 12 (2024)
The European XFEL is a megahertz repetition-rate facility producing extremely bright and coherent pulses of a few tens of femtoseconds duration. The amount of data generated in the context of user experiments can exceed hundreds of gigabits per secon
Externí odkaz:
https://doaj.org/article/c7368d3fb4224216a1f06cae7d6d28cf
Autor:
Marcin Sikorski, Marco Ramilli, Raphael de Wijn, Viktoria Hinger, Aldo Mozzanica, Bernd Schmitt, Huijong Han, Richard Bean, Johan Bielecki, Gábor Bortel, Thomas Dietze, Gyula Faigel, Konstantin Kharitonov, Chan Kim, Jayanath C. P. Koliyadu, Faisal H. M. Koua, Romain Letrun, Luis M. Lopez, Nadja Reimers, Adam Round, Abhisakh Sarma, Tokushi Sato, Miklós Tegze, Monica Turcato
Publikováno v:
Frontiers in Physics, Vol 11 (2023)
The JUNGFRAU detector is a well-established hybrid pixel detector developed at the Paul Scherrer Institut (PSI) designed for free-electron laser (FEL) applications. JUNGFRAU features a charge-integrating dynamic gain switching architecture, with thre
Externí odkaz:
https://doaj.org/article/ebe1563c26334aa8a2f5413cc0c49050
Autor:
Jayanath C. P. Koliyadu, Romain Letrun, Henry J. Kirkwood, Jia Liu, Man Jiang, Moritz Emons, Richard Bean, Valerio Bellucci, Johan Bielecki, Sarlota Birnsteinova, Raphael de Wijn, Thomas Dietze, Juncheng E, Jan Grünert, Daniel Kane, Chan Kim, Yoonhee Kim, Max Lederer, Bradley Manning, Grant Mills, Luis L. Morillo, Nadja Reimers, Dimitrios Rompotis, Adam Round, Marcin Sikorski, Cedric M. S. Takem, Patrik Vagovič, Sandhya Venkatesan, Jinxiong Wang, Ulrike Wegner, Adrian P. Mancuso, Tokushi Sato
Publikováno v:
Journal of Synchrotron Radiation, Vol 29, Iss 5, Pp 1273-1283 (2022)
Pump–probe experiments at X-ray free-electron laser (XFEL) facilities are a powerful tool for studying dynamics at ultrafast and longer timescales. Observing the dynamics in diverse scientific cases requires optical laser systems with a wide range
Externí odkaz:
https://doaj.org/article/990b647109724a02b5f51e95eb3e6980
Autor:
Susannah Holmes, Henry J. Kirkwood, Richard Bean, Klaus Giewekemeyer, Andrew V. Martin, Marjan Hadian-Jazi, Max O. Wiedorn, Dominik Oberthür, Hugh Marman, Luigi Adriano, Nasser Al-Qudami, Saša Bajt, Imrich Barák, Sadia Bari, Johan Bielecki, Sandor Brockhauser, Mathew A. Coleman, Francisco Cruz-Mazo, Cyril Danilevski, Katerina Dörner, Alfonso M. Gañán-Calvo, Rita Graceffa, Hans Fanghor, Michael Heymann, Matthias Frank, Alexander Kaukher, Yoonhee Kim, Bostjan Kobe, Juraj Knoška, Torsten Laurus, Romain Letrun, Luis Maia, Marc Messerschmidt, Markus Metz, Thomas Michelat, Grant Mills, Serguei Molodtsov, Diana C. F. Monteiro, Andrew J. Morgan, Astrid Münnich, Gisel E. Peña Murillo, Gianpietro Previtali, Adam Round, Tokushi Sato, Robin Schubert, Joachim Schulz, Megan Shelby, Carolin Seuring, Jonas A. Sellberg, Marcin Sikorski, Alessandro Silenzi, Stephan Stern, Jola Sztuk-Dambietz, Janusz Szuba, Martin Trebbin, Patrick Vagovic, Thomas Ve, Britta Weinhausen, Krzysztof Wrona, Paul Lourdu Xavier, Chen Xu, Oleksandr Yefanov, Keith A. Nugent, Henry N. Chapman, Adrian P. Mancuso, Anton Barty, Brian Abbey, Connie Darmanin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which mult
Externí odkaz:
https://doaj.org/article/2126addb96a243bbab803f29ff675139