Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Johan A Slotman"'
Autor:
Lieke Koornneef, Johan A Slotman, Esther Sleddens-Linkels, Wiggert A van Cappellen, Marco Barchi, Attila Tóth, Joost Gribnau, Adriaan B Houtsmuller, Willy M Baarends
Publikováno v:
PLoS Genetics, Vol 18, Iss 7, p e1010046 (2022)
Recombinases RAD51 and its meiosis-specific paralog DMC1 accumulate on single-stranded DNA (ssDNA) of programmed DNA double strand breaks (DSBs) in meiosis. Here we used three-color dSTORM microscopy, and a mouse model with severe defects in meiotic
Externí odkaz:
https://doaj.org/article/73600dd4da354f6792a689909bee6f67
Autor:
Johan A Slotman, Maarten W Paul, Fabrizia Carofiglio, H Martijn de Gruiter, Tessa Vergroesen, Lieke Koornneef, Wiggert A van Cappellen, Adriaan B Houtsmuller, Willy M Baarends
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008595 (2020)
The recombinase RAD51, and its meiosis-specific paralog DMC1 localize at DNA double-strand break (DSB) sites in meiotic prophase. While both proteins are required during meiotic prophase, their spatial organization during meiotic DSB repair is not fu
Externí odkaz:
https://doaj.org/article/c6b005a3f88a4c6ba0bfe10eaa0dee49
Autor:
Jeffrey Stedehouder, Demi Brizee, Johan A Slotman, Maria Pascual-Garcia, Megan L Leyrer, Bibi LJ Bouwen, Clemens MF Dirven, Zhenyu Gao, David M Berson, Adriaan B Houtsmuller, Steven A Kushner
Publikováno v:
eLife, Vol 8 (2019)
GABAergic fast-spiking parvalbumin-positive (PV) interneurons are frequently myelinated in the cerebral cortex. However, the factors governing the topography of cortical interneuron myelination remain incompletely understood. Here, we report that seg
Externí odkaz:
https://doaj.org/article/4cad7d845a4943d6bf4fae401a2ebf6e
Autor:
Shringar Rao, Shahla Romal, Bram Torenvliet, Johan A. Slotman, Tonnie Huijs, Tokameh Mahmoudi
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e30740- (2024)
Malaria, a major public health burden, is caused by Plasmodium spp parasites that first replicate in the human liver to establish infection before spreading to erythrocytes. Liver-stage malaria research has remained challenging due to the lack of a c
Externí odkaz:
https://doaj.org/article/5812a281c5e6447dbcbcf415b5e7e0d2
Autor:
Daphne J Smits, Rachel Schot, Nathalie Krusy, Katja Wiegmann, Olaf Utermöhlen, Monique T Mulder, Sandra den Hoedt, Grace Yoon, Ashish R Deshwar, Christina Kresge, Beth Pletcher, Maura van Mook, Marta Serio Ferreira, Raymond A Poot, Johan A Slotman, Gert-Jan Kremers, Abeer Ahmad, Buthaina Albash, Laila Bastaki, Dana Marafi, Jordy Dekker, Tjakko J van Ham, Laurent Nguyen, Grazia M S Mancini
Publikováno v:
Brain.
Biallelic loss-of-function variants in SMPD4 cause a rare and severe neurodevelopmental disorder with progressive congenital microcephaly and early death. SMPD4 encodes a sphingomyelinase that hydrolyses sphingomyelin into ceramide at neutral pH and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b9f4b88e557c37bd1237a4db1bf20f3
https://doi.org/10.1093/brain/awad033
https://doi.org/10.1093/brain/awad033
Autor:
Sangeetha Hari, Johan A. Slotman, Yoram Vos, Christian Floris, Wiggert A. van Cappellen, C. W. Hagen, Sjoerd Stallinga, Adriaan B. Houtsmuller, Jacob P. Hoogenboom
Publikováno v:
Scientific Reports, 12(1):20185. Nature Publishing Group
Scientific Reports, 12(1)
Scientific Reports, 12(1)
Super-resolution fluorescence microscopy can be achieved by image reconstruction after spatially patterned illumination or sequential photo-switching and read-out. Reconstruction algorithms and microscope performance are typically tested using simula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d2f7881ed2890a11a093af031fd773
http://www.scopus.com/inward/record.url?scp=85142456378&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85142456378&partnerID=8YFLogxK
Autor:
Karin Legerstee, Jason Sueters, Tsion E. Abraham, Johan A. Slotman, Gert-Jan Kremers, Jacob P. Hoogenboom, Adriaan B. Houtsmuller
Publikováno v:
Biology Open, 11(11). Company of Biologists Ltd
Biology open, 11(11)
Biology open, 11(11)
Focal adhesions (FAs) are the main cellular structures to link the intracellular cytoskeleton to the extracellular matrix. FAs mediate cell adhesion, are important for cell migration and are involved in many (patho)-physiological processes. Here we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3a70bc0da5edcba3b44853ac3a80e4
https://pure.eur.nl/en/publications/a3d5f22c-52cd-46a3-beea-6876ed45aab6
https://pure.eur.nl/en/publications/a3d5f22c-52cd-46a3-beea-6876ed45aab6
Autor:
Maurice Swinkels, Sophie Hordijk, Petra E. Bürgisser, Johan A. Slotman, Tom Carter, Frank W.G. Leebeek, A.J. Gerard Jansen, Jan Voorberg, Ruben Bierings
BackgroundPlatelet alpha-granules contain Von Willebrand factor (VWF), which is stored in eccentric alpha-granule nanodomains, and VWF propeptide (VWFpp). Differential release of VWF and VWFpp has been reported from endothelial cells. It is unclear i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5360c72825bca44a5983bd0a1bc8789
https://doi.org/10.1101/2022.10.25.513669
https://doi.org/10.1101/2022.10.25.513669
Autor:
Judith J. de Vries, Chantal Visser, Lotte Geers, Johan A. Slotman, Nadine D. van Kleef, Coen Maas, Hannelore I. Bax, Jelle R. Miedema, Eric C.M. van Gorp, Marco Goeijenbier, Johannes P.C. van den Akker, Henrik Endeman, Dingeman C. Rijken, Marieke J.H.A. Kruip, Moniek P.M. de Maat
Publikováno v:
Journal of Thrombosis and Haemostosis, 20(6), 1412-1420. Wiley-Blackwell Publishing Ltd
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 infection is associated with an increased incidence of thrombosis.OBJECTIVES: By studying the fibrin network structure of coronavirus disease 2019 (COVID-19) patients, we aimed to unravel pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a663c64845a86c6d00991b4e2c64ba
https://pubmed.ncbi.nlm.nih.gov/35316570
https://pubmed.ncbi.nlm.nih.gov/35316570