Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Johan, Peränen"'
Autor:
Reena Kumari, Katharina Ven, Megan Chastney, Shrikant B. Kokate, Johan Peränen, Jesse Aaron, Konstantin Kogan, Leonardo Almeida-Souza, Elena Kremneva, Renaud Poincloux, Teng-Leong Chew, Peter W. Gunning, Johanna Ivaska, Pekka Lappalainen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Focal adhesions (FAs) connect inner workings of cell to the extracellular matrix to control cell adhesion, migration and mechanosensing. Previous studies demonstrated that FAs contain three vertical layers, which connect extracellular matrix
Externí odkaz:
https://doaj.org/article/52ca205f2286428288ed7a744d2eb902
Autor:
Pia Runeberg-Roos, Elisa Piccinini, Anna-Maija Penttinen, Kert Mätlik, Hanna Heikkinen, Satu Kuure, Maxim M. Bespalov, Johan Peränen, Enrique Garea-Rodríguez, Eberhard Fuchs, Mikko Airavaara, Nisse Kalkkinen, Richard Penn, Mart Saarma
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 335-345 (2016)
In Parkinson's disease midbrain dopaminergic neurons degenerate and die. Oral medications and deep brain stimulation can relieve the initial symptoms, but the disease continues to progress. Growth factors that might support the survival, enhance the
Externí odkaz:
https://doaj.org/article/a3f501f9389e4ae69124b3f661ad8d55
Autor:
Elina Ikonen, Pauli Puolakkainen, György Markó-Varga, Peter Horvath, Johan Malm, Melinda Rezeli, Jeovanis Gil, Caj Haglund, Hanna Seppänen, Johan Peränen, Maarit Hölttä, Mária Kovács, Ede Migh, Yonghyo Kim, Jaana Hagström, Ábel Szkalisity, Juho Pirhonen
Supplementary Data from Lipid Metabolic Reprogramming Extends beyond Histologic Tumor Demarcations in Operable Human Pancreatic Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4904f6adcd6ea8991e71326ddf13c3
https://doi.org/10.1158/0008-5472.22432620
https://doi.org/10.1158/0008-5472.22432620
Autor:
Elina Ikonen, Pauli Puolakkainen, György Markó-Varga, Peter Horvath, Johan Malm, Melinda Rezeli, Jeovanis Gil, Caj Haglund, Hanna Seppänen, Johan Peränen, Maarit Hölttä, Mária Kovács, Ede Migh, Yonghyo Kim, Jaana Hagström, Ábel Szkalisity, Juho Pirhonen
Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest malignancies and potentially curable only with radical surgical resection at early stages. The tumor microenvironment has been shown to be central to the development and progression of PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2561d846fa068c6fdd08ce0f6dac360a
https://doi.org/10.1158/0008-5472.c.6514191
https://doi.org/10.1158/0008-5472.c.6514191
Autor:
Ilpo Vattulainen, Lauri Vanharanta, Johan Peränen, Elina Ikonen, Simon G. Pfisterer, Giray Enkavi
Publikováno v:
Traffic. 21:386-397
The human Niemann-Pick C1 (NPC1) gene encoding a 1278 amino acid protein is very heterogeneous. While some variants represent benign polymorphisms, NPC disease carriers and patients may possess rare variants, whose functional importance remains unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c675b177418f83eb4098471021c532
https://doi.org/10.1111/tra.12727
https://doi.org/10.1111/tra.12727
Autor:
Juho Pirhonen, Ábel Szkalisity, Jaana Hagström, Yonghyo Kim, Ede Migh, Mária Kovács, Maarit Hölttä, Johan Peränen, Hanna Seppänen, Caj Haglund, Jeovanis Gil, Melinda Rezeli, Johan Malm, Peter Horvath, György Markó-Varga, Pauli Puolakkainen, Elina Ikonen
Publikováno v:
Cancer research. 82(21)
Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest malignancies and potentially curable only with radical surgical resection at early stages. The tumor microenvironment has been shown to be central to the development and progression of PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362fa44ee695de8761c8f82ae6d735cb
https://pubmed.ncbi.nlm.nih.gov/36054547
https://pubmed.ncbi.nlm.nih.gov/36054547
Autor:
Tapani Viitala, Johan Peränen, Kohta Takahashi, Henriikka Kentala, Annika Koponen, Vesa M. Olkkonen, Pentti Somerharju, Amita Arora, Eeva Jääskeläinen, Elina Ikonen, Annukka M. Kivelä
Publikováno v:
Biochimie. 158:90-101
ORP2 is a sterol-binding protein with documented functions in lipid and glucose metabolism, Akt signaling, steroidogenesis, cell adhesion, migration and proliferation. Here we investigate the interactions of ORP2 with phosphoinositides (PIPs) by surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5228661ca559cd3059639dd34da0fe
https://doi.org/10.1016/j.biochi.2018.12.013
https://doi.org/10.1016/j.biochi.2018.12.013
Autor:
Anneliis Ihermann-Hella, Maria Lume, Ilkka J Miinalainen, Anniina Pirttiniemi, Yujuan Gui, Johan Peränen, Jean Charron, Mart Saarma, Frank Costantini, Satu Kuure
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004193 (2014)
Although the growth factor (GF) signaling guiding renal branching is well characterized, the intracellular cascades mediating GF functions are poorly understood. We studied mitogen-activated protein kinase (MAPK) pathway specifically in the branching
Externí odkaz:
https://doaj.org/article/eb8667839a81469e916e3de3647bc746
Autor:
Lukas Schollenberger, Thomas Gronemeyer, Christoph M Huber, Dorothee Lay, Sebastian Wiese, Helmut E Meyer, Bettina Warscheid, Rainer Saffrich, Johan Peränen, Karin Gorgas, Wilhelm W Just
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13886 (2010)
The current view of peroxisome inheritance provides for the formation of new peroxisomes by both budding from the endoplasmic reticulum and autonomous division. Here we investigate peroxisome-cytoskeleton interactions and show by proteomics, biochemi
Externí odkaz:
https://doaj.org/article/a3c61ac1974a48508872f12fb65f0838