Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Johan, Flygare"'
Autor:
Kiyoka Saito, Mark van der Garde, Terumasa Umemoto, Natsumi Miharada, Julia Sjöberg, Valgardur Sigurdsson, Haruki Shirozu, Shunsuke Kamei, Visnja Radulovic, Mitsuyoshi Suzuki, Satoshi Nakano, Stefan Lang, Jenny Hansson, Martin L. Olsson, Takashi Minami, Gunnar Gouras, Johan Flygare, Kenichi Miharada
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Hematopoietic stem cells (HSCs) react to various stress conditions. However, it is unclear whether and how HSCs respond to severe anemia. Here, we demonstrate that upon induction of acute anemia, HSCs rapidly proliferate and enhance their er
Externí odkaz:
https://doaj.org/article/c454b7e49a8c4be7938a4dfcf040f95f
Autor:
Abdul Ghani Alattar, Amanda Kristiansson, Helena Karlsson, Suvi Vallius, Jonas Ahlstedt, Eva Forssell-Aronsson, Bo Åkerström, Sven-Erik Strand, Johan Flygare, Magnus Gram
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 928 (2023)
177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) is used clinically to treat metastasized or unresectable neuroendocrine tumors (NETs). Although 177Lu-DOTATATE is mostly well tolerated in patients, bone marrow suppression and long-term ren
Externí odkaz:
https://doaj.org/article/75f059fe93d84de5ae531b78fc83fa73
Autor:
Alexander Mattebo, Taha Sen, Maria Jassinskaja, Kristýna Pimková, Isabel Prieto González-Albo, Abdul Ghani Alattar, Ramprasad Ramakrishnan, Stefan Lang, Marcus Järås, Jenny Hansson, Shamit Soneji, Sofie Singbrant, Emile van den Akker, Johan Flygare
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The YPEL family genes are highly conserved across a diverse range of eukaryotic organisms and thus potentially involved in essential cellular processes. Ypel4, one of five YPEL family gene orthologs in mouse and human, is highly and specific
Externí odkaz:
https://doaj.org/article/5dc977dcbe104bb4b3fa8157f49bbc12
Autor:
Yang Liu, Maria Dahl, Shubhranshu Debnath, Michael Rothe, Emma M. Smith, Tan Hooi Min Grahn, Sarah Warsi, Jun Chen, Johan Flygare, Axel Schambach, Stefan Karlsson
Publikováno v:
Haematologica, Vol 107, Iss 2 (2021)
Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure disorder in which pure red blood cell aplasia is associated with physical malformations and a predisposition to cancer. Twentyfive percent of patients with DBA have mutations in a gene
Externí odkaz:
https://doaj.org/article/87a6fd29702a4a00ac393a879706be89
Publikováno v:
Haematologica, Vol 105, Iss 11 (2020)
Massive expansion of erythroid progenitor cells is essential for surviving anemic stress. Research towards understanding this critical process, referred to as stress-erythropoiesis, has been hampered due to lack of specific marker-combinations enabli
Externí odkaz:
https://doaj.org/article/e63a439595ee42cdae97ec7d6609a4ed
Autor:
Gram, Abdul Ghani Alattar, Amanda Kristiansson, Helena Karlsson, Suvi Vallius, Jonas Ahlstedt, Eva Forssell-Aronsson, Bo Åkerström, Sven-Erik Strand, Johan Flygare, Magnus
Publikováno v:
Biomolecules; Volume 13; Issue 6; Pages: 928
177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) is used clinically to treat metastasized or unresectable neuroendocrine tumors (NETs). Although 177Lu-DOTATATE is mostly well tolerated in patients, bone marrow suppression and long-term ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::4f67fa76bcdc11ee9158cb85e04655d4
Autor:
Johan Flygare
Publikováno v:
Cellular Reprogramming. 24:225-227
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2218352bfb52120e6ecfa1e19fcd8f22
https://doi.org/10.1089/cell.2022.0107
https://doi.org/10.1089/cell.2022.0107
Autor:
Julian Pulecio, Oriol Alejo-Valle, Sandra Capellera-Garcia, Marianna Vitaloni, Paula Rio, Eva Mejía-Ramírez, Ilaria Caserta, Juan A. Bueren, Johan Flygare, Angel Raya
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 671-683 (2016)
Current sources of platelets for transfusion are insufficient and associated with risk of alloimmunization and blood-borne infection. These limitations could be addressed by the generation of autologous megakaryocytes (MKs) derived in vitro from soma
Externí odkaz:
https://doaj.org/article/c1bd0d0a0a724be3802e79b05af1ecf5
Autor:
Sandra Capellera-Garcia, Julian Pulecio, Kishori Dhulipala, Kavitha Siva, Violeta Rayon-Estrada, Sofie Singbrant, Mikael N.E. Sommarin, Carl R. Walkley, Shamit Soneji, Göran Karlsson, Ángel Raya, Vijay G. Sankaran, Johan Flygare
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2550-2562 (2016)
Erythroid cell commitment and differentiation proceed through activation of a lineage-restricted transcriptional network orchestrated by a group of well characterized genes. However, the minimal set of factors necessary for instructing red blood cell
Externí odkaz:
https://doaj.org/article/028787d73bf347d0853eaf6dd9814930
Autor:
Martin L. Olsson, Amanda Kristiansson, Jesper Bergwik, Abdul Ghani Alattar, Johan Flygare, Bo Åkerström, Magnus Gram, Stefan R. Hansson, Jill R. Storry, Maria Allhorn
Publikováno v:
Free Radical Biology and Medicine. 162:149-159
During red blood cell (RBC) lysis hemoglobin and heme leak out of the cells and cause damage to the endothelium and nearby tissue. Protective mechanisms exist; however, these systems are not sufficient in diseases with increased extravascular hemolys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a56a9d6f87a013b71285ed20125a6ea
https://doi.org/10.1016/j.freeradbiomed.2020.02.018
https://doi.org/10.1016/j.freeradbiomed.2020.02.018