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Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186227 (2017)
Therapeutic agents to the central nervous system (CNS) need to be efficiently delivered to the target site of action at appropriate therapeutic levels. However, a limited number of effective drugs for the treatment of neurological diseases has been d
Externí odkaz:
https://doaj.org/article/53ab403282df4af99e80368a39a39563
Autor:
Tanaka, Kazunori a, Kanno, Takuya b, Yanagisawa, Yoshiko b, Yasutake, Kaori b, Hadano, Shinji b, c, Yoshii, Fumihito d, Ikeda, Joh-E a, b, e, ⁎
Publikováno v:
In Experimental Neurology 2011 232(1):41-52
Autor:
Eiichiro Nagata, Mieko Ogino, Kounosuke Iwamoto, Yasuhisa Kitagawa, Yasuo Iwasaki, Fumihito Yoshii, Joh-E Ikeda, ALS Consortium Investigators
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149509 (2016)
OBJECTIVE:Bromocriptine mesylate (BRC), a dopamine D2 receptor agonist has been shown to confer neuroprotection, sustained motor function and slowed disease progression in mouse models of amyotrophic lateral sclerosis (ALS) Here we report a first in
Externí odkaz:
https://doaj.org/article/0f5ffb727004459ea391bc0ee4c2b3bb
Autor:
Eiichiro Nagata, Mieko Ogino, Kounosuke Iwamoto, Yasuhisa Kitagawa, Yasuo Iwasaki, Fumihito Yoshii, Joh-E Ikeda, ALS Consortium Investigators
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152845 (2016)
Externí odkaz:
https://doaj.org/article/2bb17bd36410428e863617890c9ddd5b
Autor:
Hadano, Shinji a, b, c, ⁎, Yoshii, Yasuhiro d, Otomo, Asako b, Kunita, Ryota b, Suzuki-Utsunomiya, Kyoko b, Pan, Lei b, Kakuta, Shigeru e, Iwasaki, Yasuo d, Iwakura, Yoichiro e, Ikeda, Joh-E a, b, f
Publikováno v:
In Neuroscience Research 2010 68(2):131-136
Autor:
Tanaka, Kazunori a, b, Okada, Yoshinori b, Kanno, Takuya a, b, c, Otomo, Asako d, Yanagisawa, Yoshiko a, b, c, Shouguchi-Miyata, Junko a, b, Suga, Etsuko a, b, Kohiki, Eri b, Onoe, Kyuichiro b, Osuga, Hitoshi b, Aoki, Masashi e, Hadano, Shinji c, d, Itoyama, Yasuto e, Ikeda, Joh-E a, c, d, f, ⁎
Publikováno v:
In Experimental Neurology 2008 211(2):378-386
Autor:
Kazunori Tanaka, Takuya Kanno, Yoshiko Yanagisawa, Kaori Yasutake, Satoshi Inoue, Noriaki Hirayama, Joh-E Ikeda
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87728 (2014)
Amyotrophic lateral sclerosis (ALS) is an adult-onset motor neuron degenerative disease. Given that oxidative stress and resulting chronic neuronal inflammation are thought to be central pathogenic, anti-oxidative agents and modulators of neuronal in
Externí odkaz:
https://doaj.org/article/42da0d67f6444d5f9c1db3e0aa957082
Autor:
Kunita, Ryota ‡, §, 1, Otomo, Asako ‡, 2, Mizumura, Hikaru §, Suzuki-Utsunomiya, Kyoko ‡, 1, Hadano, Shinji ‡, §, ¶, 3, Ikeda, Joh-E ‡, §, ¶, ∥, 4
Publikováno v:
In Journal of Biological Chemistry 1 June 2007 282(22):16599-16611
Autor:
Suzuki-Utsunomiya, Kyoko a, Hadano, Shinji a, b, c, Otomo, Asako a, Kunita, Ryota b, c, Mizumura, Hikaru c, Osuga, Hitoshi a, Ikeda, Joh-E a, b, c, d, ⁎
Publikováno v:
In Biochemical and Biophysical Research Communications 9 March 2007 354(2):491-497