Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joffrey L. Degoutin"'
Autor:
Marla Tipping, Carole L.C. Poon, Lucas G. Dent, Kieran F. Harvey, Xiaomeng Zhang, Joffrey L. Degoutin, Alexey Veraksa
Publikováno v:
Current Biology. 25:124-130
Summary The Salvador-Warts-Hippo (Hippo) pathway is a conserved regulator of organ size and is deregulated in human cancers [1]. In epithelial tissues, the Hippo pathway is regulated by fundamental cell biological properties, such as polarity and adh
Autor:
Kieran F. Harvey, Qi Dai, Felix A. Grusche, Eefang Yu, Joffrey L. Degoutin, Eric C. Lai, Claire C. Milton
Publikováno v:
Current Biology. 24:2673-2680
SummaryThe Salvador-Warts-Hippo (Hippo) pathway is an evolutionarily conserved regulator of organ growth and cell fate. It performs these functions in epithelial and neural tissues of both insects and mammals, as well as in mammalian organs such as t
Publikováno v:
Developmental Biology. 350:255-266
During tissue regeneration, cell proliferation replaces missing structures to restore organ function. Regenerative potential differs greatly between organs and organisms; for example some amphibians can regrow entire limbs whereas mammals cannot. The
Autor:
Marla Tipping, Eefang Yu, Floris Bosveld, Claire C. Milton, Yohanns Bellaïche, Kieran F. Harvey, Liu Yang, Alexey Veraksa, Joffrey L. Degoutin
Publikováno v:
Nature Cell Biology
Nature Cell Biology, 2013, 15 (10), pp.1176-1185. ⟨10.1038/ncb2829⟩
Nature Cell Biology, Nature Publishing Group, 2013, 15 (10), pp.1176-1185. ⟨10.1038/ncb2829⟩
Nature Cell Biology, 2013, 15 (10), pp.1176-1185. ⟨10.1038/ncb2829⟩
Nature Cell Biology, Nature Publishing Group, 2013, 15 (10), pp.1176-1185. ⟨10.1038/ncb2829⟩
International audience; The atypical cadherins Fat (Ft) and Dachsous (Ds) control tissue growth through the Salvador–Warts–Hippo (SWH) pathway, and also regulate planar cell polarity and morphogenesis. Ft and Ds engage in reciprocal signalling as
Autor:
Joshy George, Joffrey L. Degoutin, David D.L. Bowtell, Kieran F. Harvey, Elena A Takano, Stephen B. Fox, Xiaomeng Zhang, S. Deb
Publikováno v:
Oncogene. 30(25)
The Salvador-Warts-Hippo (SWH) pathway was first discovered in Drosophila melanogaster as a potent inhibitor of tissue growth. The SWH pathway is highly conserved between D. melanogaster and mammals, both in function and in the mechanism of signal tr
Autor:
Joshy George, Stephen B. Fox, David D.L. Bowtell, Kieran F. Harvey, Joffrey L. Degoutin, Xiaomeng Zhang, S. Deb, Elena A Takano
Publikováno v:
Pathology. 44:S110
Background The Salvador-Warts-Hippo (SWH) pathway was first discovered in Drosophila melanogaster as a potent inhibitor of tissue growth. It is highly conserved between species, both in the mechanism of signal transduction and function including inhi