Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Joffrey Ducroq"'
Publikováno v:
Fundamental & Clinical Pharmacology. 26:445-453
I(Ks) blockade might be a promising way to treat tachyarrhythmia because of the accumulation of activated potassium channels. However, I(Ks) blockade during ischemia/reperfusion has not been investigated. Thus, the electrophysiological effects of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99db9fdd66f166c8a72383977c459d6a
https://doi.org/10.1111/j.1472-8206.2011.00970.x
https://doi.org/10.1111/j.1472-8206.2011.00970.x
Autor:
Patrick Bois, Olivier Stucker, Elisabeth Laemmel, Jean François Faivre, Stephen G. Dilly, Stephanie Guilbot, M Le Grand, Catherine Pons-Himbert, Joffrey Ducroq, H Moha ou Maati
Publikováno v:
British Journal of Pharmacology. 159:93-101
Introduction: Doxorubicin, an anthracycline widely used in the treatment of a broad range of tumours, causes acute QT prolongation. Dexrazoxane has been shown to prevent the QT prolongation induced by another anthracycline, epirubicin, but has not ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3459a0d9eb94f3dc4a5baf5946a52acd
https://doi.org/10.1111/j.1476-5381.2009.00371.x
https://doi.org/10.1111/j.1476-5381.2009.00371.x
Autor:
Joffrey, Ducroq
Publikováno v:
Handbook of experimental pharmacology. 229
The ICH S7B document, which provides guidance for the preclinical cardiovascular evaluation of pharmaceutical new chemical entities (NCE), is essentially focused on drug-induced QT lengthening, a biomarker for the proarrhythmic adverse drug reaction,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e69c089907f060a74929b2414bad3c8
https://pubmed.ncbi.nlm.nih.gov/26091641
https://pubmed.ncbi.nlm.nih.gov/26091641
Autor:
Joffrey Ducroq
Publikováno v:
Principles of Safety Pharmacology ISBN: 9783662469422
The ICH S7B document, which provides guidance for the preclinical cardiovascular evaluation of pharmaceutical new chemical entities (NCE), is essentially focused on drug-induced QT lengthening, a biomarker for the proarrhythmic adverse drug reaction,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c101852f709841ca3628c75653d1968a
https://doi.org/10.1007/978-3-662-46943-9_8
https://doi.org/10.1007/978-3-662-46943-9_8
Autor:
Pierre Ducouret, René Rouet, Yohann Repessé, Laurent Sallé, Mathieu Ghadanfar, Paolo Emilio Puddu, Joffrey Ducroq, Jean-Louis Gérard
Publikováno v:
European Journal of Pharmacology. 532:279-289
To evaluate class III effects of clinically relevant concentrations of dofetilide (5 and 10 nmol/l) and the effects of extracellular potassium [K+]o modulation of arrhythmias onset at the level of the "border zone," we used a previously reported in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3179884756b24342e4171d3db21f44
https://doi.org/10.1016/j.ejphar.2005.12.083
https://doi.org/10.1016/j.ejphar.2005.12.083
Autor:
Pierre Ducouret, Laurent Sallé, Joffrey Ducroq, Clément Tabourel, René Rouet, Paolo Emilio Puddu, Jean-Louis Gérard
Publikováno v:
European Journal of Pharmacology. 518:165-174
There are few investigations on azimilide effects during ischemia/reperfusion. We have therefore investigated low concentrations of azimilide (0.1 and 0.5 micromol/l) versus Controls on action potential parameters and occurrence of repetitive respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ad259381973aa549f68f322bcf8231
https://doi.org/10.1016/j.ejphar.2005.06.014
https://doi.org/10.1016/j.ejphar.2005.06.014
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 81:362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28aea50231f98d47bb3044356bc256b8
https://doi.org/10.1016/j.vascn.2016.02.089
https://doi.org/10.1016/j.vascn.2016.02.089
Publikováno v:
Fundamentalclinical pharmacology. 25(3)
The electrophysiological (standard intracellular microelectrode technique) and pro-arrhythmic (occurrence of early after-depolarization) effects of five class III agents acting on delayed rectifier current (I(K)), rapid (I(Kr)), and/or slow (I(Ks)) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31b53614a7aee5ed87fe2c5a6b8e2c40
https://pubmed.ncbi.nlm.nih.gov/21241363
https://pubmed.ncbi.nlm.nih.gov/21241363
Autor:
Richard Printemps, Stephanie Guilbot, Céline Salvetat, Jean Gardette, Marie Le Grand, Joffrey Ducroq
Publikováno v:
Journal of pharmacological and toxicological methods. 56(2)
Introduction The ICHS7B guideline focused on hERG and QT assays, although other factors have also been linked with the induction of severe arrhythmias. Thus, the aim of the present study was to demonstrate that two in vitro action potential recording
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad1f32ff750115c99bf07b80315b5a4
https://pubmed.ncbi.nlm.nih.gov/17604185
https://pubmed.ncbi.nlm.nih.gov/17604185
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 75:176
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::843c9bc38f533289e35777b8d7206a1d
https://doi.org/10.1016/j.vascn.2015.08.063
https://doi.org/10.1016/j.vascn.2015.08.063