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Autor:
Lan Gao, Peter Giannousis, Martin Thoolen, Diksha Kaushik, Joey Latham, Aaron Tansy, Jiyuan Ma, Mayzie Johnston, Mandar Dali, Lee Golden, Matthew Klein, Ronald Kong, Jeffrey Trimmer
Publikováno v:
Clinical Pharmacology in Drug Development. 12:141-151
Utreloxastat (PTC857) is a 15-lipoxygenase inhibitor being developed to treat amyotrophic lateral sclerosis. This first-in-human study investigated the safety and pharmacokinetics of utreloxastat in healthy volunteers (N = 82) in a double-blind, plac