Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Joey Kuok Hoong Yam"'
Autor:
Yingdan Zhang, Bing Liang Alvin Chew, Jing Wang, Mingjun Yuan, Joey Kuok Hoong Yam, Dahai Luo, Liang Yang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2137-2146 (2023)
Pseudomonas aeruginosa is a leading cause of hospital-acquired infections. Treatment of P. aeruginosa infections is difficult given its multiple virulence mechanisms, intrinsic antibiotic resistance mechanisms, and biofilm-forming ability. Auranofin,
Externí odkaz:
https://doaj.org/article/e3f91a7eb7774cd58cda1022d7470939
Autor:
Kira Eilers, Joey Kuok Hoong Yam, Richard Morton, Adeline Mei Hui Yong, Jaime Brizuela, Corina Hadjicharalambous, Xianghui Liu, Michael Givskov, Scott A. Rice, Alain Filloux
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Pseudomonas aeruginosa is a Gram-negative bacterium that is able to survive and adapt in a multitude of niches as well as thrive within many different hosts. This versatility lies within its large genome of ca. 6 Mbp and a tight control in the expres
Externí odkaz:
https://doaj.org/article/87b01117028941d685c85514f0b940a5
Autor:
Hong Wu, Lulu Song, Joey Kuok Hoong Yam, Marian Plotkin, Hengzhuang Wang, Morten Rybtke, Dror Seliktar, Theodoros Kofidis, Niels Høiby, Tim Tolker-Nielsen, Zhijun Song, Michael Givskov
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Background and purposeBacterial biofilm infections are major health issues as the infections are highly tolerant to antibiotics and host immune defenses. Appropriate biofilm models are important to develop and improve to make progress in future biofi
Externí odkaz:
https://doaj.org/article/518e8df924894e6db40b357579eab7a9
Autor:
Mingjun Yuan, Song Lin Chua, Yang Liu, Daniela I. Drautz-Moses, Joey Kuok Hoong Yam, Thet Tun Aung, Roger W. Beuerman, May Margarette Santillan Salido, Stephan C. Schuster, Choon-Hong Tan, Michael Givskov, Liang Yang, Thomas E. Nielsen
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 3059-3069 (2018)
Antibiotic resistance threatens effective treatment of microbial infections globally. This situation has spurred the hunt for new antimicrobial compounds in both academia and the pharmaceutical industry. Here, we report how the widely used antitumor
Externí odkaz:
https://doaj.org/article/753a8d0395f842239fb8a40c6d273c36
Autor:
Shuo Sheng, Lingyi Xin, Joey Kuok Hoong Yam, May Margarette Salido, Nicole Zi Jia Khong, Qiong Liu, Rachel Andrea Chea, Hoi Yeung Li, Liang Yang, Zhao-Xun Liang, Linghui Xu
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The pathogenic bacterium Pseudomonas aeruginosa is notorious for causing acute and chronic infections in humans. The ability to infect host by P. aeruginosa is dependent on a complex cellular signaling network, which includes a large number of chemos
Externí odkaz:
https://doaj.org/article/a4a19e7637e5422980bb6cd4b877bbe3
Autor:
Su Chuen Chew, Joey Kuok Hoong Yam, Artur Matysik, Zi Jing Seng, Janosch Klebensberger, Michael Givskov, Patrick Doyle, Scott A. Rice, Liang Yang, Staffan Kjelleberg
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Mixed-species biofilms display a number of emergent properties, including enhanced antimicrobial tolerance and communal metabolism. These properties may depend on interspecies relationships and the structure of the biofilm. However, the cont
Externí odkaz:
https://doaj.org/article/d11b5ff79333434889f67fa47593faae
Autor:
Song Lin Chua, Joey Kuok Hoong Yam, Piliang Hao, Sunil S. Adav, May Margarette Salido, Yang Liu, Michael Givskov, Siu Kwan Sze, Tim Tolker-Nielsen, Liang Yang
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Pathogenic bacteria can aggregate to form biofilms and develop tolerance to antibiotics. Here, the authors use a proteomics approach to study the development of tolerance to the antibiotic colistin in Pseudomonas aeruginosabiofilms, and show that co-
Externí odkaz:
https://doaj.org/article/3ada21e3a86f427faa6e6a5a15d8d8e5
Autor:
Joyce Seow Fong Chin, Sheetal Sinha, Anjaiah Nalaparaju, Joey Kuok Hoong Yam, Zhiqiang Qin, Luyan Ma, Zhao-Xun Liang, Lanyuan Lu, Surajit Bhattacharjya, Liang Yang
Publikováno v:
Water, Vol 9, Iss 9, p 681 (2017)
Biofilm formation by opportunistic pathogens serves as one of the major causes of chronic and persistent infections. Bacterial cells in the biofilms are embedded in their self-generated protective extracellular polymeric substances (EPS), which inclu
Externí odkaz:
https://doaj.org/article/227bf95611234becad85e6be7a6eb6e7
Autor:
Victor Bochuan Wang, Joey Kuok Hoong Yam, Song-Lin Chua, Qichun Zhang, Bin Cao, Joachim Loo Say Chye, Liang Yang
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Microbial species have evolved diverse mechanisms for utilization of complex carbon sources. Proper combination of targeted species can affect bioenergy production from natural waste products. Here, we established a stable microbial consortium with E
Externí odkaz:
https://doaj.org/article/9f8fdbd8815543ae908f9280cc54f9af
Autor:
Joey Kuok Hoong Yam, Thet Tun Aung, Song Lin Chua, Yingying Cheng, Gurjeet Singh Kohli, Jianuan Zhou, Florentin Constancias, Yang Liu, Zhao Cai, May Margarette Santillan Salido, Daniela I. Drautz-Moses, Scott A. Rice, Stephan Christoph Schuster, Zhao Zhi Boo, Bin Wu, Staffan Kjelleberg, Tim Tolker-Nielsen, Rajamani Lakshminarayanan, Roger W. Beuerman, Liang Yang, Michael Givskov
Publikováno v:
Infection and immunity, 90 (8)
Yam, J K H, Aung, T T, Chua, S L, Cheng, Y, Kohli, G S, Zhou, J, Constancias, F, Liu, Y, Cai, Z, Salido, M M S, Drautz-Moses, D I, Rice, S A, Schuster, S C, Boo, Z Z, Wu, B, Kjelleberg, S, Tolker-Nielsen, T, Lakshminarayanan, R, Beuerman, R W, Yang, L & Givskov, M 2022, ' Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa ', Infection and Immunity, vol. 90, no. 8 . https://doi.org/10.1128/iai.00061-22
Yam, J K H, Aung, T T, Chua, S L, Cheng, Y, Kohli, G S, Zhou, J, Constancias, F, Liu, Y, Cai, Z, Salido, M M S, Drautz-Moses, D I, Rice, S A, Schuster, S C, Boo, Z Z, Wu, B, Kjelleberg, S, Tolker-Nielsen, T, Lakshminarayanan, R, Beuerman, R W, Yang, L & Givskov, M 2022, ' Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa ', Infection and Immunity, vol. 90, no. 8 . https://doi.org/10.1128/iai.00061-22
Pseudomonas aeruginosa is generally believed to establish biofilm-associated infections under the regulation of the secondary messenger c-di-GMP. To evaluate P. aeruginosa biofilm physiology during ocular infections, comparative transcriptomic analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faabfddccbc986ff3c6cef4e563402a5
https://hdl.handle.net/10453/164130
https://hdl.handle.net/10453/164130
