Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joey G. Sheff"'
Autor:
Martial Rey, Menglin Yang, Linda Lee, Ye Zhang, Joey G. Sheff, Christoph W. Sensen, Hynek Mrazek, Petr Halada, Petr Man, Justin L. McCarville, Elena F. Verdu, David C. Schriemer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/cdeaaca055624b1c950a6193509e26f3
Autor:
Joey G. Sheff, John F. Kelly, Anna Robotham, Traian Sulea, Félix Malenfant, Denis L’Abbé, Mélanie Duchesne, Alex Pelletier, Jean Lefebvre, Andrea Acel, Marie Parat, Mylene Gosselin, Cunle Wu, Yves Fortin, Jason Baardsnes, Henk Van Faassen, Shannon Awrey, Shawn C. Chafe, Paul C. McDonald, Shoukat Dedhar, Anne E.G. Lenferink
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Human carbonic anhydrase (hCAIX), an extracellular enzyme that catalyzes the reversible hydration of CO2, is often overexpressed in solid tumors. This enzyme is instrumental in maintaining the survival of cancer cells in a hypoxic and acidic tumor mi
Externí odkaz:
https://doaj.org/article/05ceb9ddaa0e4ba48f2d8c3227f954cc
Publikováno v:
Membranes, Vol 11, Iss 6, p 451 (2021)
Membrane proteins work within asymmetric bilayers of lipid molecules that are critical for their biological structures, dynamics and interactions. These properties are lost when detergents dislodge lipids, ligands and subunits, but are maintained in
Externí odkaz:
https://doaj.org/article/f2f5dfa650f44140b0e62c81414acacf
Autor:
Cunle Wu, Yves Fortin, Andrea Acel, Marie Parat, Denis L'Abbé, Mélanie Duchesne, Shawn C. Chafe, Jason Baardsnes, Shoukat Dedhar, Mylene Gosselin, John F. Kelly, Anna Robotham, Joey G. Sheff, Anne E.G. Lenferink, Henk van Faassen, Traian Sulea, Félix Malenfant, Paul C. McDonald, Shannon Awrey, Jean Lefebvre, Alex Pelletier
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Human carbonic anhydrase (hCAIX), an extracellular enzyme that catalyzes the reversible hydration of CO2, is often overexpressed in solid tumors. This enzyme is instrumental in maintaining the survival of cancer cells in a hypoxic and acidic tumor mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5fe5101105353d594f55bce98ca553
https://nrc-publications.canada.ca/eng/view/object/?id=b84f2488-1160-40b0-9ea8-e1ed0c1c57e9
https://nrc-publications.canada.ca/eng/view/object/?id=b84f2488-1160-40b0-9ea8-e1ed0c1c57e9
Autor:
Louis-Philippe Picard, Michael Overduin, R. Scott Prosser, Joey G. Sheff, Catharine A. Trieber
Publikováno v:
Membranes
Membranes, Vol 11, Iss 451, p 451 (2021)
Membranes, Vol 11, Iss 451, p 451 (2021)
Membrane proteins work within asymmetric bilayers of lipid molecules that are critical for their biological structures, dynamics and interactions. These properties are lost when detergents dislodge lipids, ligands and subunits, but are maintained in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722a1beed9d22176602edd65ba5f8bd1
https://nrc-publications.canada.ca/eng/view/object/?id=26e15b4b-b521-47bb-b02f-0f0c7e284cff
https://nrc-publications.canada.ca/eng/view/object/?id=26e15b4b-b521-47bb-b02f-0f0c7e284cff
Autor:
Joseph D. Schrag, Jason Baardsnes, Cassio Baptista, Marie-Ève Picard, Joey G. Sheff, Christophe Deprez, Rong Shi, Traian Sulea, Louis-Patrick Gagnon, John F. Kelly, Enrico O. Purisima, Hervé Hogues, Mahder Seifu Manenda, Francis Gaudreault
Publikováno v:
mAbs
Solution stability is an important factor in the optimization of engineered biotherapeutic candidates such as monoclonal antibodies because of its possible effects on manufacturability, pharmacology, efficacy and safety. A detailed atomic understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f893d91e93355b7cada53da7e7cb22b7
https://doi.org/10.1080/19420862.2019.1632114
https://doi.org/10.1080/19420862.2019.1632114
Autor:
Kristin Kemmerich, Danica Stanimirovic, Joey G. Sheff, Feng Ni, Eric Brunette, Ping Wang, Ping Xu, Luke Masson, John F. Kelly, Greg Hussack, Jennifer J. Hill, Mélanie Arbour, Henk van Faassen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Ligand-activated signaling through the type 1 insulin-like growth factor receptor (IGF1R) is implicated in many physiological processes ranging from normal human growth to cancer proliferation and metastasis. IGF1R has also emerged as a target for re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27b30de3b373c489869da8afc9a1189
https://doi.org/10.1038/s41598-021-83198-w
https://doi.org/10.1038/s41598-021-83198-w
Publikováno v:
The Analyst. 142:904-910
Hydrogen-deuterium exchange mass spectrometry (HX-MS) has made important contributions to the study of protein structure and function. Unfortunately, it is not known for low limits of detection, when compared with other forms of peptide-based or bott
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07fcb03597b66c0ac657f5b4888ee85
https://doi.org/10.1039/c6an02707e
https://doi.org/10.1039/c6an02707e
Autor:
Mehdi Arbabi Ghahroudi, Joey G. Sheff, Traian Sulea, Mylene Gosselin, Anne E.G. Lenferink, John C. Zwaagstra, Nazanin Rohani Larijani, Beatrice Paul Roc
Publikováno v:
Cancer Research. 80:PO-049
The tumor acidic microenvironment is a fundamental characteristic of solid tumors which distinguishes the tumor from adjacent normal tissues. This unique tumor microenvironment (TME) feature directly contributes to various aspect of tumor progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28fc2b1490f77fe5fcf19d0311a950d0
https://doi.org/10.1158/1538-7445.tumhet2020-po-049
https://doi.org/10.1158/1538-7445.tumhet2020-po-049
Autor:
Trevor F. Moraes, Christine Chieh-Lin Lai, Shaunak Raval, Nicholas Ostan, Anastassia K. Pogoutse, David C. Schriemer, Joey G. Sheff, Rong-hua Yu, Vladimir Sarpe, Anthony B. Schryvers, Morgan Hepburn, Dixon Ng
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006244 (2017)
PLoS Pathogens
PLoS Pathogens
Lactoferrin binding protein B (LbpB) is a bi-lobed outer membrane-bound lipoprotein that comprises part of the lactoferrin (Lf) receptor complex in Neisseria meningitidis and other Gram-negative pathogens. Recent studies have demonstrated that LbpB p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c9464dec866467826224a2bc4ae943
http://europepmc.org/articles/PMC5352143?pdf=render
http://europepmc.org/articles/PMC5352143?pdf=render