Zobrazeno 1 - 10
of 529
pro vyhledávání: '"Joetham A"'
Autor:
Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Angelina M. Santini, Rama Pranadinata, Casey D. Johnson, Matthew D. McGeough, Federico C. Beasley, Ryan Stansfield, Christopher McBride, Lynnie Trzoss, Hal M. Hoffman, Ariel E. Feldstein, Jeffrey A. Stafford, James M. Veal, Gretchen Bain, Erwin W. Gelfand
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The NLRP3 inflammasome is an intracellular, multiprotein complex that promotes the auto-catalytic activation of caspase-1 and the subsequent maturation and secretion of the pro-inflammatory cytokines, IL-1β and IL-18. Persistent activation
Externí odkaz:
https://doaj.org/article/a9366cea20b64379ae3b798f5d428a2d
Autor:
Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Angelina M. Santini, Rama Pranadinata, Casey D. Johnson, Matthew D. McGeough, Federico C. Beasley, Ryan Stansfield, Christopher McBride, Lynnie Trzoss, Hal M. Hoffman, Ariel E. Feldstein, Jeffrey A. Stafford, James M. Veal, Gretchen Bain, Erwin W. Gelfand
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/71601d03ca0a42d8941718d51407d3e9
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Alpha-1 antitrypsin (AAT) is a major serine protease inhibitor. AAT deficiency (AATD) is a genetic disorder characterized by early-onset severe emphysema. In well-selected AATD patients, therapy with plasma-derived AAT (pAAT), “
Externí odkaz:
https://doaj.org/article/9ee8255ff0a541978be194128084f1c0
Autor:
Joetham, Anthony, Schedel, Michaela, Ning, Fangkun, Wang, Meiqin, Takeda, Katsuyuki, Gelfand, Erwin W.
Publikováno v:
In The Journal of Allergy and Clinical Immunology March 2020 145(3):933-946
Autor:
Ning, Fangkun, Takeda, Katsuyuki, Schedel, Michaela, Domenico, Joanne, Joetham, Anthony, Gelfand, Erwin W.
Publikováno v:
In The Journal of Allergy and Clinical Immunology June 2019 143(6):2026-2037
Akademický článek
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Autor:
Makela, M. J., Kanehiro, A., Borish, L., Dakhama, A., Loader, J., Joetham, A., Xing, Z., Jordana, M., Larsen, G. L., Gelfand, E. W.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2000 May . 97(11), 6007-6012.
Externí odkaz:
https://www.jstor.org/stable/122572
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4582 (2021)
The impact of naturally occurring regulatory T cells (nTregs) on the suppression or induction of lung allergic responses in mice depends on the nuclear environment and the production of the pro-inflammatory cytokine interleukin 6 (IL-6). These activi
Externí odkaz:
https://doaj.org/article/4010725e41894eff8b92c3912d2fc1ec
Autor:
Michaela Schedel, Yi Jia, Sven Michel, Katsuyuki Takeda, Joanne Domenico, Anthony Joetham, Fangkun Ning, Matthew Strand, Junyan Han, Meiqin Wang, Joseph J. Lucas, Christian Vogelberg, Michael Kabesch, Brian P. O’Connor, Erwin W. Gelfand
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Type 2 CD8+ T cells (Tc2) play a role in the development of experimental asthma. Here the authors show that 1,25D3, the active form of vitamin D3, can prevent conversion of CD8+T cells to a Tc2 phenotype, reducing asthma susceptibility.
Externí odkaz:
https://doaj.org/article/4a78e690244b43d29f1c6343ad4eae22
Autor:
Ashino, Shigeru, Takeda, Katsuyuki, Li, Hui, Taylor, Vanessa, Joetham, Anthony, Pine, Polly R., Gelfand, Erwin W.
Publikováno v:
In The Journal of Allergy and Clinical Immunology April 2014 133(4):1162-1174