Výsledky vyhledávání - "Joern Straeter"

Biallelic inactivation of the SDHC gene in renal carcinoma associated with paraganglioma syndrome type 3

Autor: Gerd Rasp, Hartmut P. H. Neumann, Michael M. Hoffmann, Maren Sullivan, Alexander Bosse, Angelica Malinoc, Kurt Werner Schmid, Serdar Deger, Thorsten Wiech, Joern Straeter, Charis Eng, Cordula A. Jilg

Publikováno v: Endocrine-Related Cancer. 19:283-290

The etiology and pathogenesis of renal cell carcinoma (RCC) are only partially understood. Key findings in hereditary RCC, which may be site specific or a component of a syndrome, have contributed to our current understanding. Important heritable syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15e703df101c685cad6b8d7c2938959
https://doi.org/10.1530/erc-11-0324

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Thymidylate synthase expression in resectable and unresectable pancreatic cancer: role as predictive or prognostic marker?

Autor: Doris Henne-Bruns, Stephanie Denzer, Sylvia Sander, Andrea Formentini, Marko Kornmann, Joern Straeter

Publikováno v: International journal of colorectal disease. 22(1)

Thymidylate synthase (TS) is an important enzyme for DNA synthesis and the target for 5-fluorouracil (5-FU). Its expression may determine the outcome of patients with gastrointestinal cancers. We examined the prognostic and predictive value of TS-pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b527627937a42eb48465aadc5bddb3c
https://pubmed.ncbi.nlm.nih.gov/16538493

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Pre-clinical evaluation of the activity of irinotecan as a basis for regional chemotherapy

Autor: Carmen, Hofmann, Klaus, Buttenschoen, Joern, Straeter, Doris, Henne-Bruns, Marko, Kornmann

Publikováno v: Anticancer research. 25(2A)

Irinotecan alone and in combination with 5-fluorouracil (5-FU) displays potent activity in advanced colorectal cancer. The aim of this study was to estimate the potential efficacy of irinotecan for hepatic arterial infusion (HAI) chemotherapy.We inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c758605b6e38548991950bd8580ab1a9
https://pubmed.ncbi.nlm.nih.gov/15868911

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4-Hydroxy-1-(3-pyridyl)-1-butanone, an Indicator for 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone–Induced DNA Damage, Is Not Detected in Human Pancreatic Tissue

Autor: Brian Pittman, Joern Straeter, Doris Henne-Bruns, Bogdan Prokopczyk, Marco Ramadani, Karam El-Bayoumy, A. John Cunningham, Neil Trushin, Hans G. Beger, Shobha Akerkar, Gerhard Leder

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 14:540-541

Tobacco smoking is the only known etiologic agent that causes pancreatic cancer. The tobacco-specific nitrosamine 4-(methylnitrosamino)-I-(3-pyridyl)-1-butanone (NNK) is a potent carcinogen in laboratory rodents that, independent of the route of admi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba70bccb9ca9cccd004855f4559c791
https://doi.org/10.1158/1055-9965.epi-04-0626

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mRNA quantitation of thymidylate synthase and dihydropyrimidine dehydrogenase can predict disease-free survival in stage IIb and III colon and stage II and III rectal cancer

Autor: Sucan Polat, Hans G. Beger, Detlef Behnke, Wolfgang Schwabe, Peter D. Danenberg, Joern Straeter, Marko Kommann, Karl H. Link, Peter Haeussler

Publikováno v: Gastroenterology. 120:A63-A63

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe0005d8379b28015383a67a6272ea1
https://doi.org/10.1016/s0016-5085(01)80313-9

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