Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joern Linkner"'
Autor:
Julia Damiano-Guercio, Laëtitia Kurzawa, Jan Mueller, Georgi Dimchev, Matthias Schaks, Maria Nemethova, Thomas Pokrant, Stefan Brühmann, Joern Linkner, Laurent Blanchoin, Michael Sixt, Klemens Rottner, Jan Faix
Publikováno v:
eLife, Vol 9 (2020)
Cell migration entails networks and bundles of actin filaments termed lamellipodia and microspikes or filopodia, respectively, as well as focal adhesions, all of which recruit Ena/VASP family members hitherto thought to antagonize efficient cell moti
Externí odkaz:
https://doaj.org/article/5218dcb94c6e4b91a3ad1f89f9bb6945
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21327 (2011)
The Scar/WAVE-complex links upstream Rho-GTPase signaling to the activation of the conserved Arp2/3-complex. Scar/WAVE-induced and Arp2/3-complex-mediated actin nucleation is crucial for actin assembly in protruding lamellipodia to drive cell migrati
Externí odkaz:
https://doaj.org/article/433dc25552da4a7dbf0f8d270ce1ba65
Autor:
Georgi Dimchev, Michael Sixt, Matthias Schaks, Joern Linkner, Stefan Bruehmann, Laurent Blanchoin, Maria Nemethova, Klemens Rottner, Laetitia Kurzawa, Jan Mueller, Thomas Pokrant, Julia Damiano-Guercio, Jan Faix
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/eLife.55351⟩
eLife, 2020, 9, ⟨10.7554/eLife.55351⟩
England
eLife, Vol 9 (2020)
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/eLife.55351⟩
eLife, 2020, 9, ⟨10.7554/eLife.55351⟩
England
eLife, Vol 9 (2020)
International audience; Cell migration entails networks and bundles of actin filaments termed lamellipodia and microspikes or filopodia, respectively, as well as focal adhesions, all of which recruit Ena/VASP family members hitherto thought to antago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfd70b2c893a19acb0bbb6e7bcb7807
https://doi.org/10.7554/elife.55351
https://doi.org/10.7554/elife.55351
Autor:
Maria Nemethova, Klemens Rottner, Laetitia Kurzawa, Laurent Blanchoin, Matthias Schaks, Jan Mueller, Georgi Dimchev, Julia Damiano-Guercio, Michael Sixt, Joern Linkner, Thomas Pokrant, Stefan Brühmann, Jan Faix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec06585e64bb5a392493923b7e5166dd
https://doi.org/10.7554/elife.55351.sa2
https://doi.org/10.7554/elife.55351.sa2
Autor:
Klemens Rottner, Jan Faix, Stefan Bruehmann, Laetitia Kurzawa, Thomas Pokrant, Michael Sixt, Georgi Dimchev, Julia Damiano-Guercio, Joern Linkner, Jan Mueller, Laurent Blanchoin, Maria Nemethova
Cell migration entails networks and bundles of actin filaments termed lamellipodia and microspikes or filopodia, respectively, as well as focal adhesions, all of which recruit Ena/VASP family members hitherto thought to antagonize efficient cell moti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cda063e24da94299b3098638250f633
Publikováno v:
Biology of the Cell. 109:162-166
Arpin is an Arp2/3 inhibitory protein, which decreases the protrusion lifetime and hence directional persistence in the migration of diverse cells. Arpin is activated by the small GTPase Rac, which controls cell protrusion, thus closing a negative fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ced402b1138d6a856f434fe1e720973
https://doi.org/10.1111/boc.201600064
https://doi.org/10.1111/boc.201600064
Autor:
Laurent Blanchoin, Michael Sixt, Klemens Rottner, Joern Linkner, Laetitia Kurzawa, Jan Mueller, Maria Nemethova, Julia Damiano-Guercio, Georgi Dimchev, Stefan Bruehmann, Jan Faix
Publikováno v:
SSRN Electronic Journal.
Cell migration entails protrusion of the front comprising networks and bundles of actin filaments termed lamellipodia and microspikes or filopodia, respectively. Ena/VASP proteins accumulate at their tips and in focal adhesions (FA), where they presu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e39383c69b21568608aca19b4dcc3002
https://doi.org/10.2139/ssrn.3454865
https://doi.org/10.2139/ssrn.3454865
Autor:
Tobias Reinl, Klemens Rottner, Stefan Brühmann, Jan Faix, Christof Litschko, Theresia E. B. Stradal, Lothar Jänsch, Joern Linkner
Publikováno v:
European journal of cell biology. 96(8)
The WAVE regulatory complex (WRC) links upstream Rho-family GTPase signaling to the activation of the ARP2/3 complex in different organisms. WRC-induced and ARP2/3 complex-mediated actin nucleation beneath the plasma membrane is critical for actin as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b01f143cb0055d82ee18f0bd0be3e5
https://pubmed.ncbi.nlm.nih.gov/28889942
https://pubmed.ncbi.nlm.nih.gov/28889942
Publikováno v:
Biology of the Cell
Biology of the Cell, Wiley, 2017, 109 (4), pp.162-166. ⟨10.1111/boc.201600064⟩
Biology of the Cell, Wiley, 2017, 109 (4), pp.162-166. ⟨10.1111/boc.201600064⟩
International audience; Arpin is an Arp2/3 inhibitory protein, which decreases the protrusion lifetime and hence directional persistence in the migration of diverse cells. Arpin is activated by the small GTPase Rac, which controls cell protrusion, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bc144fb166ec965e7f28d002ac4bc3a3
https://hal-polytechnique.archives-ouvertes.fr/hal-01955789
https://hal-polytechnique.archives-ouvertes.fr/hal-01955789
Autor:
Roman Gorelik, Laurent Blanchoin, Ivan Bièche, Susan Fetics, Goran Lakisic, Fabienne Pierre, Violaine David, Anne-Gaëlle Planson, Klemens Rottner, Valérie Campanacci, Adeline Boyreau, Jacqueline Cherfils, Anika Steffen, Isaline Herrada, Julien G. Dumortier, Nicolas B. David, Antonina Y. Alexandrova, J. Victor Small, Tamara A. Chipysheva, Sophie Vacher, Ksenia Oguievetskaia, Joern Linkner, Christophe Guérin, Irene Dang, Florence A. Giger, Emmanuel Derivery, Maria Nemethova, Carla Sousa-Blin, Jan Faix, Nadine Peyriéras, V. D. Ermilova, Alexis Gautreau, Sophie Zinn-Justin, Véronique Henriot
Publikováno v:
Nature
Nature, Nature Publishing Group, 2013, 503 (7475), pp.281-4. ⟨10.1038/nature12611⟩
Nature, 2013, 503 (7475), pp.281-4. ⟨10.1038/nature12611⟩
Nature, Nature Publishing Group, 2013, 503 (7475), pp.281-4. ⟨10.1038/nature12611⟩
Nature, 2013, 503 (7475), pp.281-4. ⟨10.1038/nature12611⟩
International audience; Cell migration requires the generation of branched actin networks that power the protrusion of the plasma membrane in lamellipodia. The actin-related proteins 2 and 3 (Arp2/3) complex is the molecular machine that nucleates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051f40f30a5bad1ba74041b3fc9daaca
https://doi.org/10.1038/nature12611
https://doi.org/10.1038/nature12611