Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Joeri L, Aerts"'
Autor:
Sabine den Roover, Joeri L. Aerts
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102226- (2024)
Externí odkaz:
https://doaj.org/article/28413447d90347228a9fd8b3b5f9d072
Autor:
Rafaëla Schober, Bianca Brandus, Thessa Laeremans, Gilles Iserentant, Camille Rolin, Géraldine Dessilly, Jacques Zimmer, Michel Moutschen, Joeri L. Aerts, Xavier Dervillez, Carole Seguin-Devaux
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-26 (2023)
Abstract Background Combination antiretroviral therapy (cART) has dramatically extended the life expectancy of people living with HIV-1 and improved their quality of life. There is nevertheless no cure for HIV-1 infection since HIV-1 persists in vira
Externí odkaz:
https://doaj.org/article/a29cd266c542405eae82707c28909e5b
Autor:
Sabine den Roover, Joeri L. Aerts
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 545-547 (2023)
Externí odkaz:
https://doaj.org/article/2f9f13839a194052826e04ac37e82bca
Autor:
Thessa Laeremans, Sabine den Roover, Cynthia Lungu, Sigrid D’haese, Rob A. Gruters, Sabine D. Allard, Joeri L. Aerts
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Although natural killer (NK) cells have been studied in connection with dendritic cell (DC)-based vaccination in the field of cancer immunology, their role has barely been addressed in the context of therapeutic vaccination against HIV-1. In
Externí odkaz:
https://doaj.org/article/8d718e76751947ccbcc26ed725f9a812
Autor:
Jens Tijtgat, Jolien De Munck, Inès Dufait, Julia Katharina Schwarze, Ivan Van Riet, Lorenzo Franceschini, Karine Breckpot, Joeri L. Aerts, Bart Neyns, Sandra Tuyaerts
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T-VEC, a HSV-1 derived oncolytic virus, is approved for the treatment of advanced melanoma. The mechanisms that underly the systemic anti-tumor effect that is seen following intratumoral injection have not yet been studied but are likely to be mediat
Externí odkaz:
https://doaj.org/article/15bec737d36f4fb1acbc36e0fe41b1da
Autor:
Patrick Tjok Joe, Ioanna Christopoulou, Lien van Hoecke, Bert Schepens, Tine Ysenbaert, Carlo Heirman, Kris Thielemans, Xavier Saelens, Joeri L. Aerts
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background Current human influenza vaccines lack the adaptability to match the mutational rate of the virus and therefore require annual revisions. Because of extensive manufacturing times and the possibility that antigenic alterations occur
Externí odkaz:
https://doaj.org/article/c946bfff7a2147e0912ce56ac5b126eb
Autor:
Sigrid D’haese, Thessa Laeremans, Sabine den Roover, Sabine D. Allard, Guido Vanham, Joeri L. Aerts
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1387 (2022)
A major determinant for the success of mRNA-based vaccines is the composition of the nanoparticles (NPs) used for formulation and delivery. Cationic peptides represent interesting candidate carriers for mRNA, since they have been shown to efficiently
Externí odkaz:
https://doaj.org/article/87710dc59d1a4e9ca214871c1b228c74
Autor:
Bruna dos Santos Rodrigues, Kaat Leroy, Milos Mihajlovic, Sybren De Boever, Sarah Vanbellingen, Bruno Cogliati, Joeri L. Aerts, Mathieu Vinken
Publikováno v:
Archives of Toxicology. 97:1739-1751
Validated in vitro assays for testing non-genotoxic carcinogenic potential of chemicals are currently not available. Consequently, the two-year rodent bioassay remains the gold standard method for the identification of these chemicals. Transcriptomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72afaa8c36682bc9f0b8fc1e0e45a3bd
https://doi.org/10.1007/s00204-023-03486-4
https://doi.org/10.1007/s00204-023-03486-4
Autor:
Philipp Kalus, Jolien De Munck, Sarah Vanbellingen, Laura Carreer, Thessa Laeremans, Katrijn Broos, Inès Dufait, Julia K. Schwarze, Ivan Van Riet, Bart Neyns, Karine Breckpot, Joeri L. Aerts
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4865 (2022)
Recently, a paradigm shift has been established for oncolytic viruses (OVs) as it was shown that the immune system plays an important role in the specific killing of tumor cells by OVs. OVs have the intrinsic capacity to provide the right signals to
Externí odkaz:
https://doaj.org/article/8e773698b59148dcb3bad19015abcb8a
Autor:
Thessa Laeremans, Sigrid D’haese, Jonathan Aernout, Kurt Barbé, Pieter Pannus, Sofie Rutsaert, Ellen Vancutsem, Guido Vanham, Coca Necsoi, Ward De Spiegelaere, Marie Couttenye, Natacha Herssens, Marie-Angélique De Scheerder, Stéphane De Wit, Linos Vandekerckhove, Eric Florence, Joeri L. Aerts, Sabine D. Allard
Publikováno v:
AIDS
Objective(s): Suppression of viral replication in patients on antiretroviral therapy (ART) is determined by plasma viral load (pVL) measurement. Whenever pVL reaches values below the limit of quantification, the qualitative parameter 'target detected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cde8d5db4055ee64064df6b374731b
https://doi.org/10.1097/qad.0000000000003352
https://doi.org/10.1097/qad.0000000000003352