Výsledky vyhledávání - "Joeri Beauprez"

Comprehensive study on Escherichia coli genomic expression: Does position really matter?

Autor: Pieter Coussement, Sofie De Maeseneire, Nico Snoeck, Anke Goormans, Joeri Beauprez, Gert Peters, Wim Soetaert, Hannes Decadt, Dries Van Herpe, Karel Vermeulen

Publikováno v: Metabolic Engineering. 62:10-19

As a biorefinery platform host, Escherichia coli has been used extensively to produce metabolites of commercial interest. Integration of foreign DNA onto the bacterial genome allows for stable expression overcoming the need for plasmid expression and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d28555a1a9a4a9618be476d82c7c87a
https://doi.org/10.1016/j.ymben.2020.07.007

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Serine integrase recombinational engineering (SIRE): A versatile toolbox for genome editing

Autor: Nico Snoeck, Anke Goormans, Maarten De Mol, Sofie De Maeseneire, Wim Soetaert, Dries Van Herpe, Pieter Coussement, Isabelle Maryns, Gert Peters, Joeri Beauprez

Publikováno v: Biotechnology and Bioengineering

Chromosomal integration of biosynthetic pathways for the biotechnological production of high-value chemicals is a necessity to develop industrial strains with a high long-term stability and a low production variability. However, the introduction of m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fe6100f0de67fab7ede996e3d9bf1f
https://pubmed.ncbi.nlm.nih.gov/30345503

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Development of an in vivo glucosylation platform by coupling production to growth: Production of phenolic glucosides by a glycosyltransferase ofVitis vinifera

Autor: Pieter De Cocker, Stein Mincke, Jo Maertens, Frederik De Bruyn, Marjan De Mey, Christian V. Stevens, Brecht De Paepe, Joeri Beauprez

Publikováno v: Biotechnology and Bioengineering. 112:1594-1603

Glycosylation of small molecules can significantly alter their properties such as solubility, stability, and/or bioactivity, making glycosides attractive and highly demanded compounds. Consequently, many biotechnological glycosylation approaches have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc76f1eb0b1a43213ab9ac2503fe152e
https://doi.org/10.1002/bit.25570

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Biotechnological advances in UDP-sugar based glycosylation of small molecules

Autor: Frederik De Bruyn, Joeri Beauprez, Wim Soetaert, Jo Maertens, Marjan De Mey

Publikováno v: Biotechnology Advances. 33:288-302

Glycosylation of small molecules like specialized (secondary) metabolites has a profound impact on their solubility, stability or bioactivity, making glycosides attractive compounds as food additives, therapeutics or nutraceuticals. The subsequently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fa27997886e6068c68d3e37756cb3a
https://doi.org/10.1016/j.biotechadv.2015.02.005

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Making Human Milk Oligosaccharides Available for Research and Application – Approaches, Challenges, and Future Opportunities

Autor: Richard H. Furneaux, Lars Bode, Joeri Beauprez, Andrew C. Muscroft-Taylor, Stewart Campbell

Elucidation of the biological roles and more detailed structure–function relationships of human milk oligosaccharides (HMOs) requires access to homogeneous, defined HMO samples. Various approaches, including chemical synthesis, enzymatic/chemoenzym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f599b8558675e97370d184d18389d46
https://doi.org/10.1016/b978-0-12-802725-7.00009-9

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One step DNA assembly for combinatorial metabolic engineering

Autor: Pieter Coussement, Marjan De Mey, Wouter Van Bellegem, Jo Maertens, Joeri Beauprez

Publikováno v: Metabolic Engineering. 23:70-77

The rapid and efficient assembly of multi-step metabolic pathways for generating microbial strains with desirable phenotypes is a critical procedure for metabolic engineering, and remains a significant challenge in synthetic biology. Although several

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a3f3775bb45c8a5dce0b11e308cee4
https://doi.org/10.1016/j.ymben.2014.02.012

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Unraveling the Leloir Pathway of Bifidobacterium bifidum: Significance of the Uridylyltransferases

Autor: Marjan De Mey, Joeri Beauprez, Wim Soetaert, Frederik De Bruyn, Jo Maertens

Publikováno v: Applied and Environmental Microbiology. 79:7028-7035

The GNB/LNB (galacto- N -biose/lacto- N -biose) pathway plays a crucial role in bifidobacteria during growth on human milk or mucin from epithelial cells. It is thought to be the major route for galactose utilization in Bifidobacterium longum as it i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993dbd96d2d6ebdc21b26bd7f43749ef
https://doi.org/10.1128/aem.02460-13

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High yield 1,3-propanediol production by rational engineering of the 3-hydroxypropionaldehyde bottleneck in Citrobacter werkmanii

Autor: Sofie De Maeseneire, Wim Soetaert, Veerle E. T. Maervoet, Joeri Beauprez, Fatma Gizem Avci, Marjan De Mey

Publikováno v: Microbial Cell Factories
MICROBIAL CELL FACTORIES

WOS: 000368884500001
PubMed ID: 26822953
Background: Imbalance in cofactors causing the accumulation of intermediates in biosynthesis pathways is a frequently occurring problem in metabolic engineering when optimizing a production pathway i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa15bc4ca7dec14cb5004dc65284492b
http://europepmc.org/articles/PMC4731958

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Effect of iclR and arcA deletions on physiology and metabolic fluxes in Escherichia coli BL21 (DE3)

Autor: Marjan De Mey, Hendrik Waegeman, Jo Maertens, Wim Soetaert, Joeri Beauprez

Publikováno v: Biotechnology Letters. 34:329-337

Deletion of both iclR and arcA in E. coli profoundly alters the central metabolic fluxes and decreases acetate excretion by 70%. In this study we investigate the metabolic consequences of both deletions in E. coli BL21 (DE3). No significant differenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bbe6c77e7c7f733b0f5c08d7344ac5
https://doi.org/10.1007/s10529-011-0774-6

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