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pro vyhledávání: '"Joerg-Robert Leheste"'
Autor:
Joerg Robert Leheste, German eTorres
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2015)
SIRT1 deacetylase, a sensor of intermittent energy restriction, is inextricably intertwined with circadian regulation of central and peripheral clock genes. The purpose of this study was to identify SIRT1-specific target genes that are expressed in a
Externí odkaz:
https://doaj.org/article/aa10a697f3ba4cbab984761ba795934e
Autor:
Ulrike Ziegler, Annette Hammes, Jian-Kan Guo, Danilo Landrock, Marie-Claire Gubler, Gudrun Lutsch, Joerg-Robert Leheste, Andreas Schedl
Publikováno v:
Cell. 106(3):319-329
Alternative splicing of Wt1 results in the insertion or omission of the three amino acids KTS between zinc fingers 3 and 4. In vitro experiments suggest distinct molecular functions for + and −KTS isoforms. We have generated mouse strains in which