Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Joerg Stelling"'
Autor:
Javier Santos-Moreno, Eve Tasiudi, Hadiastri Kusumawardhani, Joerg Stelling, Yolanda Schaerli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Genotype networks are sets of genotypes connected by small mutational changes that share the same phenotype. They facilitate evolutionary innovation by enabling the exploration of different neighborhoods in genotype space. Genotype networks,
Externí odkaz:
https://doaj.org/article/4abb8858581e45c1b28fe834daa280a5
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Synthetic circuits based on CRISPRi have not achieved multistable and dynamic behaviors. Here the authors build an oscillator, a toggle switch and an incoherent feed-forward loop using CRISPRi, and provide a mathematical model suggesting that unspeci
Externí odkaz:
https://doaj.org/article/91079cbffa374430abcf3eb11b066066
Autor:
Sarah M Keating, Dagmar Waltemath, Matthias König, Fengkai Zhang, Andreas Dräger, Claudine Chaouiya, Frank T Bergmann, Andrew Finney, Colin S Gillespie, Tomáš Helikar, Stefan Hoops, Rahuman S Malik‐Sheriff, Stuart L Moodie, Ion I Moraru, Chris J Myers, Aurélien Naldi, Brett G Olivier, Sven Sahle, James C Schaff, Lucian P Smith, Maciej J Swat, Denis Thieffry, Leandro Watanabe, Darren J Wilkinson, Michael L Blinov, Kimberly Begley, James R Faeder, Harold F Gómez, Thomas M Hamm, Yuichiro Inagaki, Wolfram Liebermeister, Allyson L Lister, Daniel Lucio, Eric Mjolsness, Carole J Proctor, Karthik Raman, Nicolas Rodriguez, Clifford A Shaffer, Bruce E Shapiro, Joerg Stelling, Neil Swainston, Naoki Tanimura, John Wagner, Martin Meier‐Schellersheim, Herbert M Sauro, Bernhard Palsson, Hamid Bolouri, Hiroaki Kitano, Akira Funahashi, Henning Hermjakob, John C Doyle, Michael Hucka, SBML Level 3 Community members
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 8, Pp n/a-n/a (2020)
Abstract Systems biology has experienced dramatic growth in the number, size, and complexity of computational models. To reproduce simulation results and reuse models, researchers must exchange unambiguous model descriptions. We review the latest edi
Externí odkaz:
https://doaj.org/article/86e517962df24b21af078b7f951f7487
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/008ac35ff5dd4b6cb851532e13ef851f
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 4, p e1005454 (2017)
Bistability has important implications in signaling pathways, since it indicates a potential cell decision between alternative outcomes. We present two approaches developed in the framework of the Chemical Reaction Network Theory for easy and efficie
Externí odkaz:
https://doaj.org/article/6fa92fc328e64bbba43d4d67b60e0b8b
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 8, p e1005085 (2016)
Understanding cellular function requires accurate, comprehensive representations of metabolism. Genome-scale, constraint-based metabolic models (GSMs) provide such representations, but their usability is often hampered by inconsistencies at various l
Externí odkaz:
https://doaj.org/article/3da064f53d804f92982dfb5521566ccb
An introduction and overview of system modeling in biology that is accessible to researchers from different fields, including biology, computer science, mathematics, statistics, physics, and biochemistry.Research in systems biology requires the colla
Autor:
Javier Santos-Moreno, Eve Tasiudi, Hadiastri Kusumawardhani, Joerg Stelling, Yolanda Schaerli
Genotype networks are sets of genotypes connected by small mutational changes that share the same phenotype. They facilitate evolutionary innovation by enabling the exploration of different neighborhoods in genotype space. Genotype networks, first su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f01a3395acdb22754bcc6e0b0c5fe518
https://doi.org/10.1101/2022.09.01.506159
https://doi.org/10.1101/2022.09.01.506159
Autor:
Ove Øyås, Joerg Stelling
The scope of application of genome-scale constraint-based models (CBMs) of metabolic networks rapidly expands toward multicellular systems. However, comprehensive analysis of CBMs through metabolic pathway analysis remains a major computational chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::854c100aca2e1eecbf0de05282a91b8d
https://doi.org/10.1101/2020.07.31.230177
https://doi.org/10.1101/2020.07.31.230177
Autor:
Edda Klipp, Marco Antoniotti, Frank Bergmann, James C. Schaff, Peter D. Karp, Daniel Lucio, Kedar Nath Natarajan, Thomas M. Hamm, Leandro Watanabe, Henning Hermjakob, David Tolnay, John Wagner, Joerg Stelling, Alida Palmisano, Falk Schreiber, Yukiko Matsuoka, Harold F. Gómez, Huaiyu Mi, Carole J. Proctor, Ulrike Wittig, Neil Swainston, Jan Červený, Denis Thieffry, Piero Dalle Pezze, Julio Saez-Rodriguez, Maciej J. Swat, Bin Hu, Martina Kutmon, Thomas Pfau, Bas Teusink, Sarah M. Keating, Fedor A. Kolpakov, Andreas Dräger, Pedro Mendes, Martin Scharm, Emek Demir, Ioannis Xenarios, Christoph Flamm, Axel von Kamp, Darren J. Wilkinson, Nick Juty, Fengkai Zhang, Leonard A. Harris, Michael Schubert, Dagmar Waltemath, Lucian P. Smith, Steffen Klamt, Herbert M. Sauro, Ali Ebrahim, Wolfram Liebermeister, Christian Knüpfer, Nicolas Rodriguez, Tramy Nguyen, Naoki Tanimura, Christopher Cox, Stuart C. Sealfon, Nicholas Alexander Allen, Clemens Wrzodek, Bastian R. Angermann, Martin Meier-Schellersheim, Anna Zhukova, Jean-Baptiste Pettit, Hovakim Grabski, Devin P. Sullivan, Claudine Chaouiya, Michael L. Blinov, John Doyle, Ilya Kiselev, Roman Schulte, Alex Gutteridge, Mélanie Courtot, Eric Mjolsness, Finja Wrzodek, Rahuman S Malik-Sheriff, Ronan M. T. Fleming, Bruce E. Shapiro, Kimberly Begley, Leslie M. Loew, Colin S. Gillespie, Ibrahim Vazirabad, Michael Hucka, Akira Funahashi, Bernhard O. Palsson, Hamid Bolouri, Tomáš Helikar, Camille Laibe, William S. Denney, Chris T. Evelo, Florian Mittag, William S. Hlavacek, Ron Henkel, Harish Dharuri, Julien Dorier, Karthik Raman, Martina Fröhlich, Conor Lawless, Rainer Machné, Falko Krause, Damon Hachmeister, Matthias König, Clifford A. Shaffer, Benjamin D. Heavner, Douglas B. Kell, Jonathan R. Karr, Mihai Glont, Lukas Endler, Melanie I. Stefan, Robert Phair, Lu Li, Henning Schmidt, Dirk Drasdo, Johan Elf, Allyson L. Lister, Hiroaki Kitano, Richard R. Adams, Oliver A. Ruebenacker, Roland Keller, Sven Sahle, Ion I. Moraru, Gary D. Bader, Poul M. F. Nielsen, Johann M. Rohwer, Johannes Eichner, Daniel R. Hyduke, James R. Faeder, Stefan Hoops, Emanuel Gonçalves, Yuichiro Inagaki, Aurélien Naldi, Koichi Takahashi, Sylvain Soliman, Brett G. Olivier, Kieran Smallbone, Stuart L. Moodie, Pedro T. Monteiro, Chris J. Myers, Martin Golebiewski, Tomas Radivoyevitch, Jeremy Zucker, Hidde de Jong, Andrew Finney
Publikováno v:
Molecular Systems Biology
Molecular Systems Biology, 2020, 16 (8), pp.1-21. ⟨10.15252/msb.20199110⟩
Molecular systems biology, vol 16, iss 8
Molecular Systems Biology, EMBO Press, 2020, 16 (8), pp.1-21. ⟨10.15252/msb.20199110⟩
Keating, S M, Waltemath, D, König, M, Zhang, F, Dräger, A, Chaouiya, C, Bergmann, F T, Finney, A, Gillespie, C S, Helikar, T, Hoops, S, Malik-Sheriff, R S, Moodie, S L, Moraru, I I, Myers, C J, Naldi, A, Olivier, B G, Sahle, S, Schaff, J C, Smith, L P, Swat, M J, Thieffry, D, Watanabe, L, Wilkinson, D J, Blinov, M L, Begley, K, Faeder, J R, Gómez, H F, Hamm, T M, Inagaki, Y, Liebermeister, W, Lister, A L, Lucio, D, Mjolsness, E, Proctor, C J, Raman, K, Rodriguez, N, Shaffer, C A, Shapiro, B E, Stelling, J, Swainston, N, Tanimura, N, Wagner, J, Meier-Schellersheim, M, Sauro, H M, Palsson, B, Bolouri, H, Kitano, H, Funahashi, A, Hermjakob, H, Doyle, J C, Hucka, M, Adams, R R, Allen, N A, Angermann, B R, Antoniotti, M, Bader, G D, Červený, J, Courtot, M, Cox, C D, Dalle Pezze, P, Demir, E, Denney, W S, Dharuri, H, Dorier, J, Drasdo, D, Ebrahim, A, Eichner, J, Elf, J, Endler, L, Evelo, C T, Flamm, C, Fleming, R M T, Fröhlich, M, Glont, M, Gonçalves, E, Golebiewski, M, Grabski, H, Gutteridge, A, Hachmeister, D, Harris, L A, Heavner, B D, Henkel, R, Hlavacek, W S, Hu, B, Hyduke, D R, de Jong, H, Juty, N, Karp, P D, Karr, J R, Kell, D B, Keller, R, Kiselev, I, Klamt, S, Klipp, E, Knüpfer, C, Kolpakov, F, Krause, F, Kutmon, M, Laibe, C, Lawless, C, Li, L, Loew, L M, Machne, R, Matsuoka, Y, Mendes, P, Mi, H, Mittag, F, Monteiro, P T, Natarajan, K N, Nielsen, P M F, Nguyen, T, Palmisano, A, Pettit, J B, Pfau, T, Phair, R D, Radivoyevitch, T, Rohwer, J M, Ruebenacker, O A, Saez-Rodriguez, J, Scharm, M, Schmidt, H, Schreiber, F, Schubert, M, Schulte, R, Sealfon, S C, Smallbone, K, Soliman, S, Stefan, M I, Sullivan, D P, Takahashi, K, Teusink, B, Tolnay, D, Vazirabad, I, von Kamp, A, Wittig, U, Wrzodek, C, Wrzodek, F, Xenarios, I, Zhukova, A & Zucker, J 2020, ' SBML Level 3 : an extensible format for the exchange and reuse of biological models ', Molecular Systems Biology, vol. 16, no. 8, e9110, pp. 1-21 . https://doi.org/10.15252/msb.20199110
MOLECULAR SYSTEMS BIOLOGY
Molecular Systems Biology, Vol 16, Iss 8, Pp n/a-n/a (2020)
Molecular Systems Biology, 2020, 16 (8), pp.1-21. ⟨10.15252/msb.20199110⟩
Molecular systems biology, vol 16, iss 8
Molecular Systems Biology, EMBO Press, 2020, 16 (8), pp.1-21. ⟨10.15252/msb.20199110⟩
Keating, S M, Waltemath, D, König, M, Zhang, F, Dräger, A, Chaouiya, C, Bergmann, F T, Finney, A, Gillespie, C S, Helikar, T, Hoops, S, Malik-Sheriff, R S, Moodie, S L, Moraru, I I, Myers, C J, Naldi, A, Olivier, B G, Sahle, S, Schaff, J C, Smith, L P, Swat, M J, Thieffry, D, Watanabe, L, Wilkinson, D J, Blinov, M L, Begley, K, Faeder, J R, Gómez, H F, Hamm, T M, Inagaki, Y, Liebermeister, W, Lister, A L, Lucio, D, Mjolsness, E, Proctor, C J, Raman, K, Rodriguez, N, Shaffer, C A, Shapiro, B E, Stelling, J, Swainston, N, Tanimura, N, Wagner, J, Meier-Schellersheim, M, Sauro, H M, Palsson, B, Bolouri, H, Kitano, H, Funahashi, A, Hermjakob, H, Doyle, J C, Hucka, M, Adams, R R, Allen, N A, Angermann, B R, Antoniotti, M, Bader, G D, Červený, J, Courtot, M, Cox, C D, Dalle Pezze, P, Demir, E, Denney, W S, Dharuri, H, Dorier, J, Drasdo, D, Ebrahim, A, Eichner, J, Elf, J, Endler, L, Evelo, C T, Flamm, C, Fleming, R M T, Fröhlich, M, Glont, M, Gonçalves, E, Golebiewski, M, Grabski, H, Gutteridge, A, Hachmeister, D, Harris, L A, Heavner, B D, Henkel, R, Hlavacek, W S, Hu, B, Hyduke, D R, de Jong, H, Juty, N, Karp, P D, Karr, J R, Kell, D B, Keller, R, Kiselev, I, Klamt, S, Klipp, E, Knüpfer, C, Kolpakov, F, Krause, F, Kutmon, M, Laibe, C, Lawless, C, Li, L, Loew, L M, Machne, R, Matsuoka, Y, Mendes, P, Mi, H, Mittag, F, Monteiro, P T, Natarajan, K N, Nielsen, P M F, Nguyen, T, Palmisano, A, Pettit, J B, Pfau, T, Phair, R D, Radivoyevitch, T, Rohwer, J M, Ruebenacker, O A, Saez-Rodriguez, J, Scharm, M, Schmidt, H, Schreiber, F, Schubert, M, Schulte, R, Sealfon, S C, Smallbone, K, Soliman, S, Stefan, M I, Sullivan, D P, Takahashi, K, Teusink, B, Tolnay, D, Vazirabad, I, von Kamp, A, Wittig, U, Wrzodek, C, Wrzodek, F, Xenarios, I, Zhukova, A & Zucker, J 2020, ' SBML Level 3 : an extensible format for the exchange and reuse of biological models ', Molecular Systems Biology, vol. 16, no. 8, e9110, pp. 1-21 . https://doi.org/10.15252/msb.20199110
MOLECULAR SYSTEMS BIOLOGY
Molecular Systems Biology, Vol 16, Iss 8, Pp n/a-n/a (2020)
Systems biology has experienced dramatic growth in the number, size, and complexity of computational models. To reproduce simulation results and reuse models, researchers must exchange unambiguous model descriptions. We review the latest edition of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa48af775634bdfd1c248e236b20ef61
http://hdl.handle.net/10281/282956
http://hdl.handle.net/10281/282956