Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joerg Ruschel"'
Autor:
Sarah A. Woller, Joerg Ruschel, Barbara Morquette, James Cardia, Dinxue Yan, Katherine Holton, Taisia Shmushkovich, Emily Niederst, Karen Bulock, Alexey Wolfson, Matthew Abbinanti, Alyson E. Fournier, Lisa McKerracher, Kenneth M. Rosen
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104379- (2022)
Summary: The therapeutic use of RNAi has grown but often faces several hurdles related to delivery systems, compound stability, immune activation, and on-target/off-tissue effects. Self-delivering RNAi (sdRNA) molecules do not require delivery agents
Externí odkaz:
https://doaj.org/article/ac37080eac5e4e00b5d86c3ffc8224e3
Autor:
Janne Koskimäki, Thomas R. Moore, Nicholas Hobson, Amy Peiper, Rhonda Lightle, James K. Liao, Issam A. Awad, Robert Shenkar, Kenneth M. Rosen, Douglas A. Marchuk, Joerg Ruschel, Ying Cao, Lisa McKerracher, Romuald Girard, Matthew D. Abbinanti, Carol J. Gallione
Publikováno v:
Transl Stroke Res
Cavernous angioma (CA) is a vascular pathology caused by loss of function in one of the 3 CA genes (CCM1, CCM2, and CCM3) that result in rho kinase (ROCK) activation. We investigated a novel ROCK2 selective inhibitor for the ability to reduce brain l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb09a43d18645df4f1a6091c55029a8
https://doi.org/10.1007/s12975-019-00725-8
https://doi.org/10.1007/s12975-019-00725-8
Autor:
Sarah A. Woller, Joerg Ruschel, Barbara Morquette, James Cardia, Dinxue Yan, Katherine Holton, Taisia Shmushkovich, Emily Niederst, Karen Bulock, Alexey Wolfson, Matthew Abbinanti, Alyson E. Fournier, Lisa McKerracher, Kenneth M. Rosen
Publikováno v:
iScience. 25(6)
The therapeutic use of RNAi has grown but often faces several hurdles related to delivery systems, compound stability, immune activation, and on-target/off-tissue effects. Self-delivering RNAi (sdRNA) molecules do not require delivery agents or excip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0ec2aff67a81cdb6819da9bafbc234
https://pubmed.ncbi.nlm.nih.gov/35620420
https://pubmed.ncbi.nlm.nih.gov/35620420