Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Joerg R. Schlehofer"'
Autor:
Irina Kiprianova, Ali Ayache, Michele Klein, Nadja Thomas, Barbara Leuchs, Manuel Fischer, Joerg R. Schlehofer, Jean Rommelaere
Publikováno v:
Clinical Cancer Research. 17:5333-5342
Purpose: In previous studies, we have shown that the apathogenic rat parvovirus H-1 (H-1PV) is capable to induce regression of advanced symptomatic rat and human gliomas in a rat model, when the virus was injected in the tumor (intracranially) or int
Autor:
Karsten Geletneky, Andreas D. Hartkopf, Robert Krempien, Jean Rommelaere, Joerg R. Schlehofer
Publikováno v:
Bioengineered Bugs. 1:429-433
The prognosis of malignant brain tumors remains extremely bad in spite of moderate improvements of conventional treatments. A promising alternative approach is the use of oncolytic viruses. Strategies to improve viral toxicity include the combination
Autor:
Ruediger Ridder, Joerg R. Schlehofer, Michael Aulmann, Eduard Ryschich, Sven Eisold, Jan Schmidt, Michael Linnebacher, Magnus von Knebel Doeberitz, Susanne Dihlmann
Publikováno v:
International Journal of Cancer. 100:606-614
Drug resistance and toxic side effects are major limiting factors in the clinical use of antineoplastic chemotherapy. Patients with pancreatic cancer generally do not benefit from chemotherapy. The nonpathogenic adeno-associated virus type 2 (AAV-2)
Autor:
Ottheinz Krebs, Bernard Huber, Jean Rommelaere, Karsten Geletneky, Magnus von Knebel Doeberitz, Jacek Hajda, Johannes Huesing, Barbara Leuchs, Joerg R. Schlehofer, Michael Dahm
Publikováno v:
BMC Cancer
BMC Cancer, Vol 12, Iss 1, p 99 (2012)
BMC Cancer, Vol 12, Iss 1, p 99 (2012)
Background The treatment of patients with malignant brain tumors remains a major oncological problem. The median survival of patients with glioblastoma multiforme (GBM), the most malignant type, is only 15 months after initial diagnosis and even less
Autor:
Zahari Raykov, Karsten Geletneky, Laurent Daeffler, Assia L. Angelova, Jean Rommelaere, Joerg R. Schlehofer, Christiane Dinsart, Irina Kiprianova
Publikováno v:
Cytokinegrowth factor reviews. 21(2-3)
The experimental infectivity and excellent tolerance of some rodent autonomous parvoviruses in humans, together with their oncosuppressive effects in preclinical models, speak for the inclusion of these agents in the arsenal of oncolytic viruses unde
Autor:
Joerg R. Schlehofer, Karsten Geletneky, Jean Rommelaere, Andreas D. Hartkopf, Robert Krempien
Publikováno v:
Journal of Biomedicine and Biotechnology, Vol 2010 (2010)
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology
Purpose. To elucidate the influence of ionizing radiation (IR) on the oncolytic activity of Parvovirus H-1 (H-1PV) in human high-grade glioma cells.Methods. Short term cultures of human high-grade gliomas were irradiated at different doses and infect
Autor:
Alexander Kotsis, Themistoklis Mikos, Joerg R. Schlehofer, Sofia Chrisafi, John N. Bontis, Theodoros Agorastos, Brigitte Schlehofer, Alexandros Lambropoulos, Theodoros C. Constandinides
Publikováno v:
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 17(4)
The aim of this study was to investigate whether adeno-associated virus (AAV) infection can be associated with a reduced risk for human papillomavirus (HPV)-related cervical neoplasia. The study was a prospective descriptive analysis of the prevalenc
Autor:
Joerg R. Schlehofer, Karsten Geletneky, Jan J. Cornelis, Jean Rommelaere, Marta Herrero y Calle, Christel Herold-Mende
Publikováno v:
International journal of cancer. 109(1)
The extremely poor prognosis of malignant gliomas requires the investigation of other than standard therapies, i.e., the application of oncolytic viruses. In our study, we evaluated the effects of the oncosuppressive parvovirus H-1 on different estab
Autor:
Marta Herrero y Calle, Jan J. Cornelis, Christel Herold-Mende, Jean Rommelaere, Joerg R. Schlehofer
Publikováno v:
International Journal of Cancer; 3/10/2004, Vol. 109 Issue 1, p76-84, 9p