Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Joerg R. Leheste"'
Publikováno v:
The Lancet Regional Health. Americas, Vol 14, Iss , Pp 100325- (2022)
Summary: While the use of medical and recreational cannabis is rapidly expanding under state jurisdiction, the convolution of federal regulations is obstructing research progress to the detriment of healthcare equity and the protection of vulnerable
Externí odkaz:
https://doaj.org/article/e0bdfacd3fea4999bcfdaf09197c4925
Publikováno v:
Heliyon, Vol 6, Iss 5, Pp e04047- (2020)
Oxytocin plays an important role in the regulation of parturition as this peptide hormone promotes uterine smooth muscle contractility in gravid women undergoing labor. Here, we review the impact of Pitocin administration on behavioral outcomes in th
Externí odkaz:
https://doaj.org/article/c2c19fc419b34b9d87dd2b925e71fadc
Autor:
German Torres, Patrick D. Frisella, Salman J. Yousuf, Samina Sarwar, Lauren Baldinger, Sherry M. Zakhary, Joerg R. Leheste
Publikováno v:
BioTechniques, Vol 44, Iss 7S, Pp xii-xiv (2008)
The mammalian protein deacetylase SIRT1 (sirtuin 1) is widely recognized for its link to calorie restriction and longevity. SIRT1 not only modulates the function of protein targets such as p53 or NFkappaB, but it also affects gene transcription by ca
Externí odkaz:
https://doaj.org/article/96eb266c38d04212bc4f59c12dec005a
Publikováno v:
Cureus.
For almost five decades, the US Supreme Court had protected the right to abortion care in the United States. However, the Court's decision in 'Dobbs versus Jackson Women's Health Organization' in 2022 established that the US Constitution does not con
Publikováno v:
Cureus. 14(11)
Context Parkinson's disease (PD) is the second most common neurodegenerative disorder and causes many clinical manifestations including bradykinesia, tremor, postural instability, and musculoskeletal stiffness. Neurodegeneration is commonly associate
Publikováno v:
Cureus
An estimated 95-97% of Parkinson's disease (PD) cases are idiopathic, emphasizing the absence of a clear etiologic linkage for this debilitating, neurodegenerative, and progressive motor disease. Increasing evidence suggests a peripheral disease orig
Publikováno v:
SSRN Electronic Journal.
The human brain is constantly exposed to air pollutants, some of which might be disruptive or even lethal to certain neurons implicated in abstract features of cognitive function. In this review, we present new evidence from behavioral and neural stu
Autor:
Joerg R. Leheste, Tony A Slieman
The field of immunology has exponentially expanded in the last few decades. This has much to do with the recent mapping effort of the human microbiome and discoveries of crosstalk, symbiosis, opportunism and disease. Along with a better understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d4172ed7efd39c374633966fc715158
https://doi.org/10.1016/bs.mim.2020.01.001
https://doi.org/10.1016/bs.mim.2020.01.001
Publikováno v:
The Anatomical Record. 301:1251-1257
Mammalian cells accumulate DNA lesions when they undergo phases of the cell cycle or during normal cellular activity. In this regard, several DNA repair signaling pathways have evolved to maintain genome stability and avoid the potential acquisition
Autor:
Joshua A. Cuoco, Sherry M. Zakhary, Kyle Hitscherich, Christopher L. Hoehmann, German Torres, Joerg R. Leheste
Publikováno v:
The Anatomical Record. 300:1973-1980
Patients who harbor brain arteriovenous malformations are at risk for intracranial hemorrhage. These malformations are often seen in inherited vascular diseases such as hereditary hemorrhagic telangiectasia. However, malformations within the brain al