Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joerg Kleeff"'
Autor:
Ulrich Ronellenfitsch, Juliane Friedrichs, Johannes Vey, Samuel Zimmermann, Johannes Klose, Elisabeth Wadewitz, Maurizio Grilli, Joerg Kleeff, Artur Rebelo
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction Perforated peptic ulcers are a life-threatening complication associated with high morbidity and mortality. Several treatment approaches are available. The aim of this network meta-analysis (NMA) is to compare surgical and alternative app
Externí odkaz:
https://doaj.org/article/02606e725044411894f6d7f1e660e8d0
Autor:
Michelle A. Klose, Jens Walldorf, Marko Damm, Sebastian Krug, Johannes Klose, Ulrich Ronellenfitsch, Joerg Kleeff, Patrick Michl, Jonas Rosendahl
Publikováno v:
Therapeutic Advances in Gastrointestinal Endoscopy, Vol 16 (2023)
Background: Endoscopic approaches in the treatment of transmural esophageal defects, either after esophageal resection or due to perforation, have demonstrated convincing feasibility. Surgical options are limited and associated with high morbidity an
Externí odkaz:
https://doaj.org/article/26d8a05248fb41b1a6db8c3fe6902692
Autor:
Sebastian Krug, Laura Mattheis, Monika Haemmerle, Jonas Rosendahl, Joerg Kleeff, Patrick Michl
Publikováno v:
Cancer Reports, Vol 5, Iss 3, Pp n/a-n/a (2022)
Abstract Background To date, no biomarkers exist to predict response or resistance to immunotherapy in hepatocellular carcinoma (HCC). Recent approaches to classify HCC into different immunological states revealed a negative correlation between Wnt/
Externí odkaz:
https://doaj.org/article/d42d71996d2441b983f3ca2b157c7a28
Autor:
Ulrich Ronellenfitsch, Christoph W. Michalski, Patrick Michl, Sebastian Krug, Joerg Ukkat, Joerg Kleeff
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Introduction: Pancreatic cancer continues to have a poor outcome. Many patients are diagnosed with advanced disease, and in a considerable proportion, abutment or invasion of visceral arteries is present. Moreover, some patients have anatomical varia
Externí odkaz:
https://doaj.org/article/e39ec1ab950041de9d38ed5f0e13a412
Autor:
Christopher Heeschen, Mert Erkan, Joerg Kleeff, Manuel Hidalgo, Irene Miranda-Lorenzo, Catarina R. Vieira, Michele Cioffi, Bruno Sainz, Sara Maria Trabulo, Morten Dræby Sørensen, Anamaria Balic
PDF - 48K, Table S1. List of utilized primers. Table S2. List of utilized antibodies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239b01958abb3b356a6cab145fb6699e
https://doi.org/10.1158/1535-7163.22500090
https://doi.org/10.1158/1535-7163.22500090
Autor:
Christopher Heeschen, Mert Erkan, Joerg Kleeff, Manuel Hidalgo, Irene Miranda-Lorenzo, Catarina R. Vieira, Michele Cioffi, Bruno Sainz, Sara Maria Trabulo, Morten Dræby Sørensen, Anamaria Balic
Pancreatic ductal adenocarcinoma is one of the deadliest carcinomas and is characterized by highly tumorigenic and metastatic cancer stem cells (CSC). CSCs evade available therapies, which preferentially target highly proliferative and more different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1b137ed5e752867380d7d0a6e8cb83
https://doi.org/10.1158/1535-7163.c.6536352.v1
https://doi.org/10.1158/1535-7163.c.6536352.v1
Autor:
Christopher Heeschen, Mert Erkan, Joerg Kleeff, Manuel Hidalgo, Irene Miranda-Lorenzo, Catarina R. Vieira, Michele Cioffi, Bruno Sainz, Sara Maria Trabulo, Morten Dræby Sørensen, Anamaria Balic
PDF - 3180K, Figure S1. Chloroquine does not affect differentiated cancer cells. Figure S2. Chloroquine eliminates pancreatic cancer stem cells. Figure S3. Autophagy is not mediating the effect of chloroquine on primary PDAC cells. Figure S4. Chloroq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5633bb70ef8c7c403555618b1186355a
https://doi.org/10.1158/1535-7163.22500096
https://doi.org/10.1158/1535-7163.22500096
Autor:
Christopher Heeschen, Mert Erkan, Joerg Kleeff, Manuel Hidalgo, Irene Miranda-Lorenzo, Catarina R. Vieira, Michele Cioffi, Bruno Sainz, Sara Maria Trabulo, Morten Dræby Sørensen, Anamaria Balic
PDF - 147K, Supplementary methods including related references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cea9ae7dadb000c3cc101299a4940fb
https://doi.org/10.1158/1535-7163.22500093.v1
https://doi.org/10.1158/1535-7163.22500093.v1
Autor:
Christopher Heeschen, Bruno Sainz, Joerg Kleeff, Mert Erkan, William Greenhalf, Eithne Costello, Manuel Hidalgo, Sara Trabulo, Michele Cioffi
Supplementary figures 1-4. Supplementary Figure 1 - CD47 expression in pancreatic cancer (stem) cells; Supplementary Figure 1 - CD47 expression in pancreatic cancer (stem) cells; Supplementary Figure 2 - Anti-CD47 effects in a ratio 1:1 with pancreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d57a2e64c42d508d321fe3afa177c2
https://doi.org/10.1158/1078-0432.22456905
https://doi.org/10.1158/1078-0432.22456905
Autor:
Christopher Heeschen, Bruno Sainz, Joerg Kleeff, Mert Erkan, William Greenhalf, Eithne Costello, Manuel Hidalgo, Sara Trabulo, Michele Cioffi
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a cancer of the exocrine pancreas with unmet medical need and is strongly promoted by tumor-associated macrophages (TAM). The presence of TAMs is associated with poor clinical outcome, and their ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d48d07a92afcac1c4e0ca70be7aaf4
https://doi.org/10.1158/1078-0432.c.6523449
https://doi.org/10.1158/1078-0432.c.6523449