Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Joerg G. Moser"'
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 39:13-18
The natural drug, paclitaxel (taxol), is highly effectiveas a tumor chemotherapeuticwith a low probability of inducing chemoresistance,but shows severe toxic side effectsat the therapeutic dose. How can this toxicitybe overcome? Here we report the sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13051842e5fa7f6361d526e64d673b3d
https://doi.org/10.1023/a:1008114826524
https://doi.org/10.1023/a:1008114826524
Porphyrins and phthalocyanines as model compounds for detoxification of tumor chemotherapeutic drugs
Autor:
Joerg G. Moser
Publikováno v:
Journal of Porphyrins and Phthalocyanines. :129-135
The fluorescence behavior of porphyrins and phthalocyanines allows one to discriminate between monomeric and associated states of the dyes. These criteria are necessary prerequisites to decide about the inclusion behaviour of the dyes in oligomeric c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1bf8e29772c774713107385d719e075
https://doi.org/10.1002/(sici)1099-1409(200001/02)4:1<129::aid-jpp212>3.0.co
https://doi.org/10.1002/(sici)1099-1409(200001/02)4:1<129::aid-jpp212>3.0.co
Autor:
Raimund Kaufmann, Sonja Andrees, Bernhard Spengler, Dieter Kirsch, B. Roeder, Joerg G. Moser, A. Ruebner, W. Decker
Publikováno v:
Journal of Inclusion Phenomena and Molecular Recognition in Chemistry. 27:69-84
The aim of our investigation was to develop carrier systems for an application of inert drugs in photodynamic cancer therapy. β-Cyclodextrin dimers linked at their primary and secondary faces by spacers of varying lengths were synthesized as carrier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b20e1e78d26f8fa3f39673f7e4525f8
https://doi.org/10.1023/a:1007942308945
https://doi.org/10.1023/a:1007942308945
Autor:
Alexander V. Priezzhev, Anja Vervoorts, Anna N. Yaroslavsky, Ilya Yaroslavsky, Hans-Joachim Schwarzmaier, Joerg G. Moser
Publikováno v:
SPIE Proceedings.
We determined and compared to the optical properties of five samples obtained from xenotransplanted chick embryos chorio- allantoic membrane tumors, five samples obtained from xenotransplanted chick embryos yolk sac membrane tumors, and five samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bddd11ee20cd666f73a39f20a82ae5cc
https://doi.org/10.1117/12.335799
https://doi.org/10.1117/12.335799
Publikováno v:
Photochemotherapy: Photodynamic Therapy and Other Modalities III.
Photodynamic therapy (PDT)-induced kinetics of apoptosis were studied in V79 cells using several differently localized photosensitizing dyes, mostly tetraphenylporphine derivatives. Apoptotic fractions were quantified by flow cytometry after staining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01c5a92b155c601feb340171c83ef133
https://doi.org/10.1117/12.297798
https://doi.org/10.1117/12.297798
Autor:
Irina G. Meerovich, Eugeny A. Lukyanets, Alexander P. Savitsky, Oleg L. Kaliya, Joerg G. Moser, Raisa I. Yakubovskaya
Publikováno v:
Photochemotherapy: Photodynamic Therapy and Other Modalities III.
It is well established that the selectivity of accumulation of photosensitizer in malignant tissues determines largely the efficiency of photodynamic therapy. Existing photosensitizers have insufficient selectivity. Thus the conjugates of photosensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbe93dd707bd11eff5afccfdcd6f65dd
https://doi.org/10.1117/12.297826
https://doi.org/10.1117/12.297826
Publikováno v:
Photochemotherapy: Photodynamic Therapy and Other Modalities III.
The accumulation of antibodies or their fragments in tumor tissues is a basal requirement for immunotargeting of tumors in vivo. Immunotargeting is the first step for a polyphasic tumor therapy and diagnosis. Usually the high interstitial pressure an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a0293e91a219e4e0e0f9ad206943511
https://doi.org/10.1117/12.297799
https://doi.org/10.1117/12.297799
Autor:
Joerg G. Moser, Eugeny A. Lukyanets, Marina V. Demcheva, Gelii V. Ponomarev, Alexander P. Savitzki
Publikováno v:
SPIE Proceedings.
Polybiotinylated porphyrinoids and linear alkyl-dibiotins were used to describe accumulation behavior of avidin and POD-labelled avidin on tumor cells preincubated with biotinylated monoclonal antibodies. The accumulation behavior followed more a lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2f45a2331d66a8f973f9e2e516088db
https://doi.org/10.1117/12.260750
https://doi.org/10.1117/12.260750
Publikováno v:
SPIE Proceedings.
The accumulation of fluorescent dyes and anticancer drugs in tumors is a fundamental requirement for tumor-diagnosis and therapy. We tested various photosensitizers on vascularized microtumors in the hen's egg test system according to their distribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f6f47ee632f3de67f56a756cd098e10
https://doi.org/10.1117/12.260791
https://doi.org/10.1117/12.260791
Autor:
Dieter Kirsch, Anja Vervoorts, Birgit Wagner, Michael Berghahn, Joerg G. Moser, Dirk Kusch, Franz-Peter Montforts, Angelika C. Rueck, Nermin Akguen, Sonja Andrees
Publikováno v:
SPIE Proceedings.
Diglycosylated porphyrinoids were shown to stack at the outer cell membrane of tumor cells in vitro. Similar phototoxicities are acquired as with the non-glycosylated drugs at amounts of only 1% of that normally taken up of the non-glycosylated drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7766abf746a5ab536daaae8a23e5218d
https://doi.org/10.1117/12.260749
https://doi.org/10.1117/12.260749