Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Joerg D Hoeck"'
Autor:
Zachary Clemens, Sruthi Sivakumar, Abish Pius, Amrita Sahu, Sunita Shinde, Hikaru Mamiya, Nathaniel Luketich, Jian Cui, Purushottam Dixit, Joerg D Hoeck, Sebastian Kreuz, Michael Franti, Aaron Barchowsky, Fabrisia Ambrosio
Publikováno v:
eLife, Vol 10 (2021)
Aging is accompanied by disrupted information flow, resulting from accumulation of molecular mistakes. These mistakes ultimately give rise to debilitating disorders including skeletal muscle wasting, or sarcopenia. To derive a global metric of growin
Externí odkaz:
https://doaj.org/article/709d9a59e7ce49fba7ee50bebd5fa3c3
Autor:
Ganapati V Hegde, Cecile de la Cruz, Jennifer M Giltnane, Lisa Crocker, Avinashnarayan Venkatanarayan, Gabriele Schaefer, Debra Dunlap, Joerg D Hoeck, Robert Piskol, Florian Gnad, Zora Modrusan, Frederic J de Sauvage, Christian W Siebel, Erica L Jackson
Publikováno v:
eLife, Vol 8 (2019)
Squamous cell carcinomas (SCCs) account for the majority of cancer mortalities. Although TP63 is an established lineage-survival oncogene in SCCs, therapeutic strategies have not been developed to target TP63 or it’s downstream effectors. In this s
Externí odkaz:
https://doaj.org/article/6f4e75535ef4450d90e11913cada4356
Autor:
Dan Xu, Minghui Yao, Yaqing Wang, Ling Yuan, Joerg D Hoeck, Jingwen Yu, Liang Liu, Yvonne Y C Yeap, Weiya Zhang, Feng Zhang, Yinghang Feng, Tiantian Ma, Yujie Wang, Dominic C H Ng, Xiaoyin Niu, Bing Su, Axel Behrens, Zhiheng Xu
Publikováno v:
PLoS Biology, Vol 16, Iss 12, p e2006613 (2018)
Mutations of WD repeat domain 62 (WDR62) lead to autosomal recessive primary microcephaly (MCPH), and down-regulation of WDR62 expression causes the loss of neural progenitor cells (NPCs). However, how WDR62 is regulated and hence controls neurogenes
Externí odkaz:
https://doaj.org/article/10394521c613474994f3be209b267415
Autor:
Ashirwad Merve, Xinyu Zhang, Nicola Pomella, Serena Acquati, Joerg D. Hoeck, Anaelle Dumas, Gabriel Rosser, Yichen Li, Jennie Jeyapalan, Silvia Vicenzi, Qianhai Fan, Zeng Jie Yang, Arianna Sabò, Denise Sheer, Axel Behrens, Silvia Marino
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Choroid plexus tumours (CPTs) account for 2–5% of brain tumours in children. They can spread along the neuraxis and can recur after treatment. Little is known about the molecular mechanisms underlying their formation and only few high fide
Externí odkaz:
https://doaj.org/article/124de95b234e4a8aad17a71b1c6fbb08
Autor:
Ye Feng, Wei-Lin Qiu, Xin-Xin Yu, Yu Zhang, Mao-Yang He, Lin-Chen Li, Li Yang, Weiyi Zhang, Michael Franti, Junqing Ye, Joerg D. Hoeck, Cheng-Ran Xu
Publikováno v:
Molecular Metabolism, Vol 37, Iss , Pp 100982- (2020)
Objectives: The streptozotocin (STZ) model is widely used in diabetes research. However, the cellular and molecular states of pancreatic endocrine cells in this model remain unclear. This study explored the molecular characteristics of islet cells tr
Externí odkaz:
https://doaj.org/article/861d48b0c873482a960a2b7e3a62336d
Autor:
Ashirwad Merve, Xinyu Zhang, Nicola Pomella, Serena Acquati, Joerg D. Hoeck, Anaelle Dumas, Gabriel Rosser, Yichen Li, Jennie Jeyapalan, Silvia Vicenzi, Qianhai Fan, Zeng Jie Yang, Arianna Sabò, Denise Sheer, Axel Behrens, Silvia Marino
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-1 (2019)
In the original version of this article [1], there was 1 error in the affiliation of the European Institute of Oncology (affiliation 3). In this correction article the updated affiliation is shown for clarification.
Externí odkaz:
https://doaj.org/article/2cc49146c06e48cda6fef5ed68f93a65
Autor:
Axel Behrens, Atanu Chakraborty, Joerg D. Hoeck, Emma Nye, Clive Da Costa, Gavin Kelly, Markus E. Diefenbacher, Julian Downward, E. Josue Ruiz, Linxiang Lan, Bradley Spencer-Dene, Jean-Pierre David, Eva M. Riising
Publikováno v:
JCI Insight
The AP-1 transcription factor c-Jun is required for Ras-driven tumorigenesis in many tissues and is considered as a classical proto-oncogene. To determine the requirement for c-Jun in a mouse model of K-RasG12D-induced lung adenocarcinoma, we inducib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f2d01a568224a2eabb7f4301d7d6cc
https://doi.org/10.1172/jci.insight.124985
https://doi.org/10.1172/jci.insight.124985
Autor:
Yichen Li, Axel Behrens, Ashirwad Merve, Zeng-Jie Yang, Nicola Pomella, Silvia Marino, Joerg D. Hoeck, Anaelle A. Dumas, Denise Sheer, Xinyu Zhang, Serena Acquati, Arianna Sabò, Jennie N. Jeyapalan, Qianhai Fan, Silvia Vicenzi, Gabriel Rosser
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-18 (2019)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Choroid plexus tumours (CPTs) account for 2–5% of brain tumours in children. They can spread along the neuraxis and can recur after treatment. Little is known about the molecular mechanisms underlying their formation and only few high fidelity mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b35c42b1925d0a8c971a7bc99b8ff33
http://link.springer.com/article/10.1186/s40478-019-0739-x
http://link.springer.com/article/10.1186/s40478-019-0739-x
Autor:
Hikaru Mamiya, Abish Pius, Purushottam D. Dixit, Amrita Sahu, Aaron Barchowsky, Sruthi Sivakumar, Michael Franti, Sunita Shinde, Nathaniel Luketich, Joerg D. Hoeck, Jian Cui, Sebastian Kreuz, Zachary Clemens, Fabrisia Ambrosio
Publikováno v:
eLife, Vol 10 (2021)
Aging is accompanied by disrupted information flow, resulting from accumulation of molecular mistakes. These mistakes ultimately give rise to debilitating disorders including skeletal muscle wasting, or sarcopenia. To derive a global metric of growin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a614ed8ccc0fb0f1db30eddcbaffcfac
https://doi.org/10.7554/elife.61138
https://doi.org/10.7554/elife.61138
Autor:
Abish Pius, Purushottam D. Dixit, Aaron Barchowsky, Nathaniel Luketich, Hikaru Mamiya, Michael Franti, Amrita Sahu, Jian Cui, Sruthi Sivakumar, Sebastian Kreuz, Fabrisia Ambrosio, Joerg D. Hoeck, Sunita Shinde, Zachary Clemens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4801657ccc9728577e02080f3facb41d
https://doi.org/10.7554/elife.61138.sa2
https://doi.org/10.7554/elife.61138.sa2
