Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Joerg, Czech"'
Autor:
Blanc, Jan
Publikováno v:
Simiolus: Netherlands Quarterly for the History of Art, 2002 Jan 01. 29(3/4), 210-213.
Externí odkaz:
https://www.jstor.org/stable/3780937
Autor:
WESTSTEIJN, THIJS
Publikováno v:
Oud Holland, 2004 Jan 01. 117(1/2), 103-105.
Externí odkaz:
https://www.jstor.org/stable/42711689
Autor:
Sven Ruf, Sridharan Rajagopal, Sanjay Venkatachalapathi Kadnur, Mahanandeesha S. Hallur, Shilpa Rani, Rajendra Kristam, Srinivasan Swaminathan, Bharat Ravindra Zope, Pavan Kumar Gondrala, Indu Swamy, V. P. Rama Kishore Putta, Saravanan Kandan, Gernot Zech, Herman Schreuder, Christine Rudolph, Ralf Elvert, Joerg Czech, Swarnakumari Birudukota, M. Amir Siddiqui, Niranjan Naranapura Anand, Vishal Subhash Mane, Sreekanth Dittakavi, Juluri Suresh, Ramachandraiah Gosu, Mullangi Ramesh, Takeshi Yura, Saravanakumar Dhakshinamoorthy, Aimo Kannt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Nicotinamide N-methyltransferase (NNMT) is a metabolic regulator that catalyzes the methylation of nicotinamide (Nam) using the co-factor S-adenosyl-L-methionine to form 1-methyl-nicotinamide (MNA). Overexpression of NNMT and the presence of
Externí odkaz:
https://doaj.org/article/1bd53e86e70b4c66b07f2146adca9f2e
Autor:
Aimo Kannt, Sridharan Rajagopal, Mahanandeesha S. Hallur, Indu Swamy, Rajendra Kristam, Saravanakumar Dhakshinamoorthy, Joerg Czech, Gernot Zech, Herman Schreuder, Sven Ruf
Publikováno v:
Molecules, Vol 26, Iss 4, p 991 (2021)
Nicotinamide-N-methyltransferase (NNMT) is a cytosolic enzyme catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to nicotinamide (Nam). It is expressed in many tissues including the liver, adipose tissue, and skeletal muscle.
Externí odkaz:
https://doaj.org/article/61332a9f60cc407593eef5ac0b48e04f
Autor:
Patrick Shum, Thomas Licher, John L. Kane, Carolin Gerbeth-Kreul, Gerhard Hessler, Antje Pommereau, Sven Ruf, Christian Engel, Linli Wei, Joerg Czech, Theresa A Kuntzweiler
Publikováno v:
SLAS Discovery. 26:783-797
Classical high-throughput screening (HTS) technologies for the analysis of ionic currents across biological membranes can be performed using fluorescence-based, radioactive, and mass spectrometry (MS)-based uptake assays. These assays provide rapid r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44e4fb083c4e35d492c537df0250e79a
https://doi.org/10.1177/24725552211011180
https://doi.org/10.1177/24725552211011180
Autor:
Carolin, Gerbeth-Kreul, Antje, Pommereau, Sven, Ruf, John L, Kane, Theresa, Kuntzweiler, Gerhard, Hessler, Christian K, Engel, Patrick, Shum, LinLi, Wei, Joerg, Czech, Thomas, Licher
Publikováno v:
SLAS discovery : advancing life sciences RD. 26(6)
Classical high-throughput screening (HTS) technologies for the analysis of ionic currents across biological membranes can be performed using fluorescence-based, radioactive, and mass spectrometry (MS)-based uptake assays. These assays provide rapid r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9160baf68ccf7faf0016023ba5f4dc1
https://pubmed.ncbi.nlm.nih.gov/33955247
https://pubmed.ncbi.nlm.nih.gov/33955247
Autor:
Indu N. Swamy, Mahanandeesha S. Hallur, Saravanakumar Dhakshinamoorthy, Rajendra Kristam, Sven Ruf, Aimo Kannt, Sridharan Rajagopal, Gernot Zech, Herman Schreuder, Joerg Czech
Publikováno v:
Molecules
Volume 26
Issue 4
Molecules, Vol 26, Iss 991, p 991 (2021)
Volume 26
Issue 4
Molecules, Vol 26, Iss 991, p 991 (2021)
Nicotinamide-N-methyltransferase (NNMT) is a cytosolic enzyme catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to nicotinamide (Nam). It is expressed in many tissues including the liver, adipose tissue, and skeletal muscle.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304d1f534180ae4303006d998f29ee1a
Autor:
Nisha K. Anchan, Thomas Langer, Vishal Subhash Mane, Raghunadha Reddy Burri, Christine Rudolph, Herman Schreuder, Joerg Czech, Ramachandraiah Gosu, Rajendra Kristam, Saravanakumar Dhakshinamoorthy, Ramesh Mullangi, Juluri Suresh, Mahanandeesha S. Hallur, Sridharan Rajagopal, Takeshi Yura, Manvi Singh, Aimo Kannt, Devaraj Venkatapura Chandrasekar, Shama Shaik, Sanjay Venkatachalapathi Kadnur, V.P. Rama Kishore Putta, Lokesh Kananti Narasimhulu, Karthikai Raj Murugesan, Ravi Kanth Bhamidipati, Sven Ruf, Indu N. Swamy, Alexander Marker, Sayantani Sarkar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:922-925
Nicotinamide N-methyltransferase (NNMT) has been linked to obesity and diabetes. We have identified a novel nicotinamide (NA) analog, compound 12 that inhibited NNMT enzymatic activity and reduced the formation of 1-methyl-nicotinamide (MNA), the pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0692f15941b73b65689828e71e37e26f
https://doi.org/10.1016/j.bmcl.2018.01.058
https://doi.org/10.1016/j.bmcl.2018.01.058
Die Digitalisierung des Kulturbetriebs gewinnt endlich an Fahrt! Das liegt nicht zuletzt an den Corona-Beschränkungen, denn die Errungenschaften der virtuellen Transformation sind im Zuge der Lockdowns schon jetzt zur notwendigen Bedingung für ein
Autor:
Martin Lorenz, Hans Peter Nestler, Otmar Klingler, Monica Donghi, Manfred Schudok, Herman Schreuder, Hauke Szillat, Joerg Czech, Hans Matter
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(14)
The amidinophenylurea scaffold was earlier shown to provide an excellent template for the synthesis of novel and potent inhibitors of the blood coagulation factor VIIa. In this contribution we describe the structure-based design of potent ligands gui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c797729e937c8a11a93b66f7815fd006
https://pubmed.ncbi.nlm.nih.gov/15203149
https://pubmed.ncbi.nlm.nih.gov/15203149