Conformational Changes of Myoglobin Upon Interaction with Negatively-Charged Phospholipid Vesicles

Autor: Joep J. Bergers, Louis van Bloois, Yechezkel Barenholz, Daan J.A. Crommelin

Publikováno v: Journal of Liposome Research. 5:311-326

The interaction between m yoglobin and negatively-charged liposonies composed of phosphatidylcholine/phosphatidylglycerol (1 : 1) was studied at low ionic strength under acidic conditions. Changes in the absorbance and the fluorescence spectra of niy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cff8435d288bc60125aa2c48c51b132
https://doi.org/10.3109/08982109509018632

Critical factors for liposome-incorporated tumour-associated antigens to induce protective tumour immunity to SL2 lymphoma cells in mice

Autor: Willem Den Otter, Hub F.J. Dullens, Monique W. H. Mimpen, P. A. Steerenberg, Jan Willem B. de Groot, Joep J. Bergers, Daan J.A. Crommelin

Publikováno v: Cancer Immunology, Immunotherapy. 37:271-279

Physical and immunogenic properties of reconstituted membranes designed for the presentation of tumour-associated antigens (TAA) to the immune system are described. Proteins and lipids of crude membranes of SL2 murine lymphosarcoma cells were partial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68563de8ee87adf35b78751cdc31a733
https://doi.org/10.1007/bf01518522

Inhibition of cytomegalovirus late antigen expression and cytomegalovirus replication in human fibroblasts and differentiated monocytic cells by liposome-encapsulated foscarnet

Autor: Susan V. Snijders, Ulrich R Hengge, Joep J. Bergers, Irma A. J. M. Bakker-Woudenberg

Publikováno v: Journal of Controlled Release, 163-171. Elsevier
ISSUE=47;STARTPAGE=163;ENDPAGE=171;ISSN=0168-3659;TITLE=Journal of Controlled Release

Foscarnet is one of the drugs of choice for the treatment of cytomegalovirus (CMV) infections, but its efficacy is limited by systemic toxicity, poor penetration into cells and a short plasma half-life. In this study, two types of sized, foscarnet-co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a18315d3eb4921c34d0a6c11cc9decb
https://pure.eur.nl/en/publications/c2e5defc-bb4c-4bab-aebb-866248593253

Effect of immunomodulators on specific tumor immunity induced by liposome-encapsulated tumor-associated antigens

Autor: Margreet P. G. Filius, P. A. Steerenberg, Hub F.J. Dullens, Jan Willem B. de Groot, Willem Den Otter, Daan J.A. Crommelin, Joep J. Bergers

Publikováno v: International journal of cancer. 56(5)

Reconstituted membranes consist of liposomal structures formed by removal of detergent from solubilized membrane constituents. The membrane-like configuration of reconstituted membranes makes them attractive as vehicles for presentation of tumor-asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584d509d0a0dde3a49c74beb70f3b5d3
https://pubmed.ncbi.nlm.nih.gov/8314349

Reconstituted membranes of tumour cells (proteoliposomes) induce specific protection to murine lymphoma cells

Autor: P. A. Steerenberg, Joep J. Bergers, Hub F.J. Dullens, Jan Willem B. de Groot, Adriana W. De Blois, Willem Den Otter, Daan J.A. Crommelin

Publikováno v: Cancer immunology, immunotherapy : CII. 34(4)

Antigens presented on cell membranes or on liposomes are usually more immunogenic than antigens in soluble form, this being one of the reasons for the weak immunogenicity of extracted tumour-associated transplantation antigens (TATA). The main object

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2dfaefb0b0bf480cb2659a92d160a5
https://pubmed.ncbi.nlm.nih.gov/1537056