Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Joelle C. Boulos"'
Autor:
Jana Ismail, Wassim N. Shebaby, Joey Daher, Joelle C. Boulos, Robin Taleb, Costantine F. Daher, Mohamad Mroueh
Publikováno v:
Plants, Vol 13, Iss 1, p 93 (2023)
Daucus carota L., a member of the Apiaceae family, comprises 13 subspecies, with one being cultivated (D. carota L. ssp. sativus (Hoffm.) Arcang.) and the remaining being wild. Traditionally, the wild carrot has been recognized for its antilithic, di
Externí odkaz:
https://doaj.org/article/7a2f0ae0f71e4d89a80a94f429513934
Publikováno v:
Molecules, Vol 28, Iss 15, p 5658 (2023)
The c-MYC oncogene regulates multiple cellular activities and is a potent driver of many highly aggressive human cancers, such as leukemia and triple-negative breast cancer. The oxadiazole class of compounds has gained increasing interest for its ant
Externí odkaz:
https://doaj.org/article/03d6c39c01394436bb4489264b473131
Autor:
Mohamed Elbadawi, Joelle C. Boulos, Mona Dawood, Min Zhou, Waseem Gul, Mahmoud A. ElSohly, Sabine M. Klauck, Thomas Efferth
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1107 (2023)
The proto-oncogenic transcription factor c-MYC plays a pivotal role in the development of tumorigenesis, cellular proliferation, and the control of cell death. Its expression is frequently altered in many cancer types, including hematological maligna
Externí odkaz:
https://doaj.org/article/23a580f186cd44e38c6dd828fe7df242
Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo
Autor:
Luay J. Rashan, Nadire Özenver, Joelle C. Boulos, Mona Dawood, Wynand P. Roos, Katrin Franke, Ioannis Papasotiriou, Ludger A. Wessjohann, Heinz-Herbert Fiebig, Thomas Efferth
Publikováno v:
Molecules, Vol 28, Iss 4, p 1871 (2023)
Cancer drug resistance remains a major obstacle in clinical oncology. As most anticancer drugs are of natural origin, we investigated the anticancer potential of a standardized cold-water leaf extract from Nerium oleander L., termed Breastin. The phy
Externí odkaz:
https://doaj.org/article/7cc8ee3d74db4551ba4c7fc7cdeb880e
Autor:
Sami A. Khalid, Mona Dawood, Joelle C. Boulos, Monica Wasfi, Assia Drif, Faranak Bahramimehr, Nasim Shahhamzehei, Letian Shan, Thomas Efferth
Publikováno v:
Molecules, Vol 27, Iss 18, p 5858 (2022)
The chemotherapy of tumors is frequently limited by the development of resistance and severe side effects. Phytochemicals may offer promising candidates to meet the urgent requirement for new anticancer drugs. We screened 69 phytochemicals, and focus
Externí odkaz:
https://doaj.org/article/2ba61851db5c4a9d9c3ec6e00b369c12
Publikováno v:
Journal of Natural Products. 86:131-137
The first total syntheses of the orchid-derived natural products isoarundinin I (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6bb5329462c0adb9e1f18de02df1e4
https://doi.org/10.1021/acs.jnatprod.2c00830
https://doi.org/10.1021/acs.jnatprod.2c00830
Autor:
Joelle C. Boulos, Mohamed E. M. Saeed, Manik Chatterjee, Yagmur Bülbül, Francesco Crudo, Doris Marko, Markus Munder, Sabine M. Klauck, Thomas Efferth
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1126 (2021)
Crizotinib was a first generation of ALK tyrosine kinase inhibitor approved for the treatment of ALK-positive non-small-cell lung carcinoma (NSCLC) patients. COMPARE and cluster analyses of transcriptomic data of the NCI cell line panel indicated tha
Externí odkaz:
https://doaj.org/article/0287c6085c9e4590b630f9d66419fce4
Autor:
MOHAMED E. M. SAEED, JOELLE C. BOULOS, SABRINA B. MÜCKLICH, ELLEN LEICH, MANIK CHATTERJEE, SABINE M. KLAUCK, THOMAS EFFERTH
Publikováno v:
Cancer Genomics Proteomics
Background/Aim: Multiple myeloma (MM) is characterized by accumulation of a malignant clone of plasma cells in the bone marrow. Curative treatments are not yet available. Therefore, we undertook a drug repurposing approach to identify possible candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbb3d11d80c6a2a2c24edf4463a1a6f
https://pubmed.ncbi.nlm.nih.gov/35985681
https://pubmed.ncbi.nlm.nih.gov/35985681
Autor:
Markus Munder, Francesco Crudo, Yagmur Bülbül, Thomas Efferth, Mohamed E.M. Saeed, Manik Chatterjee, Sabine M. Klauck, Joelle C. Boulos, Doris Marko
Publikováno v:
Pharmaceuticals
Volume 14
Issue 11
Pharmaceuticals, Vol 14, Iss 1126, p 1126 (2021)
Volume 14
Issue 11
Pharmaceuticals, Vol 14, Iss 1126, p 1126 (2021)
Crizotinib was a first generation of ALK tyrosine kinase inhibitor approved for the treatment of ALK-positive non-small-cell lung carcinoma (NSCLC) patients. COMPARE and cluster analyses of transcriptomic data of the NCI cell line panel indicated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24d6ed9e4b105f0a15a7414da1dea81
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/25025
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/25025
Publikováno v:
Natural Product Communications. 16:1934578X2199335
Cordycepin is one of the substantial components of the parasitic fungus Cordyceps sinensis as well as other Cordyceps species. It exerts various effects such as antimetastatic, antiinflammatory, antioxidant, and neuroprotective activities. Assorted s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae8ff39fdb79c2cc5d24111c2933e81e
https://doi.org/10.1177/1934578x21993350
https://doi.org/10.1177/1934578x21993350