Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Joell L. Solan"'
Autor:
Rasha Al-attar, Joseph Jargstorf, Rocco Romagnuolo, Mariam Jouni, Faisal J. Alibhai, Paul D. Lampe, Joell L. Solan, Michael A. Laflamme
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 61 (2024)
The transplantation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) has shown promise in preclinical models of myocardial infarction, but graft myocardium exhibits incomplete host–graft electromechanical integration and a propensit
Externí odkaz:
https://doaj.org/article/78cf26346a0b476b8ceddafac10f4217
Autor:
Dominic Filice, Wahiba Dhahri, Joell L. Solan, Paul D. Lampe, Erin Steele, Nikita Milani, Benjamin Van Biber, Wei-Zhong Zhu, Tamilla Sadikov Valdman, Rocco Romagnolo, José David Otero-Cruz, Kip D. Hauch, Matthew W. Kay, Narine Sarvazyan, Michael A. Laflamme
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-18 (2020)
Abstract Background Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) show tremendous promise for cardiac regeneration, but the successful development of hESC-CM-based therapies requires improved tools to investigate their electrical behavi
Externí odkaz:
https://doaj.org/article/7f1f8dac3ed3440dba9a6860419e0e8d
Autor:
Dominic Filice, Wahiba Dhahri, Joell L. Solan, Paul D. Lampe, Erin Steele, Nikita Milani, Benjamin Van Biber, Wei-Zhong Zhu, Tamilla Sadikov Valdman, Rocco Romagnuolo, José David Otero-Cruz, Kip D. Hauch, Matthew W. Kay, Narine Sarvazyan, Michael A. Laflamme
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/e7f83734d9ba469499f8b1185acc6d74
Autor:
Joell L. Solan, Paul D. Lampe
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1596 (2020)
The gap junction protein Connexin43 (Cx43) is highly regulated by phosphorylation at over a dozen sites by probably at least as many kinases. This Cx43 “kinome” plays an important role in gap junction assembly and turnover. We sought to gain a be
Externí odkaz:
https://doaj.org/article/5d24e5334496475693a30178556da2a1
Autor:
Kristin J. Lastwika, Andrew Kunihiro, Joell L. Solan, Yuzheng Zhang, Lydia R. Taverne, David Shelley, Jung-Hyun Rho, Timothy W. Randolph, Christopher I. Li, Eric L. Grogan, Pierre P. Massion, Annette L. Fitzpatrick, David MacPherson, A. McGarry Houghton, Paul D. Lampe
Publikováno v:
Science Translational Medicine. 15
Small cell lung cancer (SCLC) elicits the generation of autoantibodies that result in unique paraneoplastic neurological syndromes. The mechanistic basis for the formation of such autoantibodies is largely unknown but is key to understanding their et
Autor:
Janis M. Burt, Paul D. Lampe, Joell L. Solan, Maura L. Cotter, Josef Vagner, Jose F. Ek-Vitorin, Scott Boitano
Publikováno v:
American Journal of Physiology-Cell Physiology. 317:C825-C842
Connexin (Cx) mimetic peptides derived from extracellular loop II sequences (e.g., Gap27: SRPTEKTIFII; Peptide5: VDCFLSRPTEKT) have been used as reversible, Cx-specific blockers of hemichannel (HCh) and gap junction channel (GJCh) function. These blo
Autor:
Paul D. Lampe, Joell L. Solan
Publikováno v:
Biomolecules
Biomolecules, Vol 10, Iss 1596, p 1596 (2020)
Volume 10
Issue 12
Biomolecules, Vol 10, Iss 1596, p 1596 (2020)
Volume 10
Issue 12
The gap junction protein Connexin43 (Cx43) is highly regulated by phosphorylation at over a dozen sites by probably at least as many kinases. This Cx43 &ldquo
kinome&rdquo
plays an important role in gap junction assembly and turnover. We so
kinome&rdquo
plays an important role in gap junction assembly and turnover. We so
Publikováno v:
Oncogene
Pancreatic ductal adenocarcinoma (PDA) is aggressive, highly metastatic and characterized by a robust desmoplasia. Connexin proteins that form gap junctions have been implicated in tumor suppression for over 30 years. Cx43, the most widely expressed
Autor:
Filice, Dominic, Dhahri, Wahiba, Joell L. Solan, Lampe, Paul D., Steele, Erin, Milani, Nikita, Biber, Benjamin Van, Zhu, Wei-Zhong, Valdman, Tamilla Sadikov, Romagnuolo, Rocco, Otero-Cruz, José David, Hauch, Kip D., Kay, Matthew W., Sarvazyan, Narine, Laflamme, Michael A.
Additional file 5: Supplementary Fig. S5. In vitro optical action potentials from cardiomyocytes from multiple hESC lines. A, B: Representative fluorescence traces from WT or GCaMP3 cardiomyocyte aggregates generated from either the H7 (A) or RUES2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25280bc83f2ea5f5d18aaaf5b6f1f375
Autor:
Filice, Dominic, Dhahri, Wahiba, Joell L. Solan, Lampe, Paul D., Steele, Erin, Milani, Nikita, Biber, Benjamin Van, Zhu, Wei-Zhong, Valdman, Tamilla Sadikov, Romagnolo, Rocco, Otero-Cruz, José David, Hauch, Kip D., Kay, Matthew W., Sarvazyan, Narine, Laflamme, Michael A.
Additional file 2: Supplementary Fig. S2. Spectra of GCaMP3 and di-2-ANEPEQ in hESC-CMs in vitro. A: Absorbance (ABS) and emission (EM) spectra of di-2-ANEPEQ by spectrofluorimetry after loading into hESC-CMs. Note di-2-ANEPEQ-loaded hESC-CMs absorb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b6582a4350f28bccc1aba3073a1efb