Abnormalities in intron retention characterize patients with systemic lupus erythematosus

Autor: Xiaoqian Sun, Zhichao Liu, Zongzhu Li, Zhouhao Zeng, Weiqun Peng, Jun Zhu, Joel Zhao, Chenghao Zhu, Chen Zeng, Nathaniel Stearrett, Keith A. Crandall, Prathyusha Bachali, Amrie C. Grammer, Peter E. Lipsky

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Abstract Regulation of intron retention (IR), a form of alternative splicing, is a newly recognized checkpoint in gene expression. Since there are numerous abnormalities in gene expression in the prototypic autoimmune disease systemic lupus erythemat

Externí odkaz: https://doaj.org/article/a8bb4a17c0e94138a63c314e77341310

Late presentation in adolescent idiopathic scoliosis: who, why, and how often?

Autor: Joel Zhao Jie Lee, Derrick Jun Liang Lam, Kevin Boon Leong Lim

Publikováno v: Journal of pediatric orthopedics. Part B. 23(1)

Children and young teenagers with adolescent idiopathic scoliosis (AIS) not infrequently present with Cobb angles in excess of 40° at the first clinic visit. This study aimed to establish the incidence of this group of patients, identify the possibl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81adee0b5ed37d81e71992493de0ae51
https://pubmed.ncbi.nlm.nih.gov/24201070

Abnormalities in intron retention characterize patients with systemic lupus erythematosus.

Autor: Sun, Xiaoqian¹ (AUTHOR), Liu, Zhichao² (AUTHOR), Li, Zongzhu² (AUTHOR), Zeng, Zhouhao² (AUTHOR), Peng, Weiqun² (AUTHOR), Zhu, Jun³ (AUTHOR), Zhao, Joel⁴ (AUTHOR), Zhu, Chenghao⁵ (AUTHOR), Zeng, Chen² (AUTHOR) chenz@gwu.edu, Stearrett, Nathaniel⁶ (AUTHOR), Crandall, Keith A.⁶ (AUTHOR) kcrandall@gwu.edu, Bachali, Prathyusha⁷ (AUTHOR), Grammer, Amrie C.⁷ (AUTHOR), Lipsky, Peter E.⁷ (AUTHOR) peterlipsky@comcast.net

Publikováno v: Scientific Reports. 3/29/2023, Vol. 13 Issue 1, p1-10. 10p.

New Lupus Findings from George Washington University Described (Abnormalities in intron retention characterize patients with systemic lupus erythematosus).

Publikováno v: Genomics & Genetics Weekly; 4/21/2023, p802-802, 1p