Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Joel Z Nordin"'
Autor:
Antje M. Zickler, Xiuming Liang, Dhanu Gupta, Doste R. Mamand, Mariacristina De Luca, Giulia Corso, Lorenzo Errichelli, Justin Hean, Titash Sen, Omnia M. Elsharkasy, Noriyasu Kamei, Zheyu Niu, Guannan Zhou, Houze Zhou, Samantha Roudi, Oscar P. B. Wiklander, André Görgens, Joel Z. Nordin, Virginia Castilla‐Llorente, Samir EL Andaloussi
Publikováno v:
Advanced Science, Vol 11, Iss 42, Pp n/a-n/a (2024)
Abstract Messenger RNA (mRNA) has emerged as an attractive therapeutic molecule for a plethora of clinical applications. For in vivo functionality, mRNA therapeutics require encapsulation into effective, stable, and safe delivery systems to protect t
Externí odkaz:
https://doaj.org/article/57285ee9b4914259979d9194d408bdbc
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Abstract Background and main body Pharmacokinetics (PK) and pharmacodynamics (PD) are central concepts to guide the dosage and administration of drug therapies and are essential to consider for both healthcare professionals and researchers in therape
Externí odkaz:
https://doaj.org/article/56c04af6edb64a13b86f110e4d4e7302
Autor:
Doste R. Mamand, Safa Bazaz, Dara K. Mohammad, Xiuming Liang, Svetlana Pavlova, Carsten Mim, Susanne Gabrielsson, Joel Z. Nordin, Oscar P. B. Wiklander, Manuchehr Abedi‐Valugerdi, Samir EL‐Andaloussi
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Haematopoiesis dysregulation with the presence of immature myeloid and erythroid immunosuppressive cells are key characteristics of the immune escape phase of tumour development. Here, the role of in vitro generated B16F10 tumour cell‐deri
Externí odkaz:
https://doaj.org/article/1c7ed4f843a74655872ea6309bf7b745
Autor:
Wenyi Zheng, Julia Rädler, Helena Sork, Zheyu Niu, Samantha Roudi, Jeremy P. Bost, André Görgens, Ying Zhao, Doste R. Mamand, Xiuming Liang, Oscar P. B. Wiklander, Taavi Lehto, Dhanu Gupta, Joel Z. Nordin, Samir EL Andaloussi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Extracellular vesicles (EVs) are gaining ground as next-generation drug delivery modalities. Genetic fusion of the protein of interest to a scaffold protein with high EV-sorting ability represents a robust cargo loading strategy. To address
Externí odkaz:
https://doaj.org/article/622f51f2cad347f4917ee57145e74779
Autor:
Joel Z. Nordin
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 10, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/9c3b1aaa07904de7a747fed1b80cb49b
Autor:
Xiuming Liang, Zheyu Niu, Valentina Galli, Nathalie Howe, Ying Zhao, Oscar P. B. Wiklander, Wenyi Zheng, Rim Jawad Wiklander, Giulia Corso, Christopher Davies, Justin Hean, Eleni Kyriakopoulou, Doste R. Mamand, Risul Amin, Joel Z. Nordin, Dhanu Gupta, Samir EL Andaloussi
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 7, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) have shown promise as potential therapeutics for the treatment of various diseases. However, their rapid clearance after administration could be a limitation in certain therapeutic settings. To solve this, an eng
Externí odkaz:
https://doaj.org/article/9620878d96184d60a46da34441e162df
Autor:
William J. Valentine, Sherif A. Mostafa, Suzumi M. Tokuoka, Fumie Hamano, Natsuko F. Inagaki, Joel Z. Nordin, Norio Motohashi, Yoshihiro Kita, Yoshitsugu Aoki, Takao Shimizu, Hideo Shindou
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
In Duchenne muscular dystrophy (DMD), lack of dystrophin increases the permeability of myofiber plasma membranes to ions and larger macromolecules, disrupting calcium signaling and leading to progressive muscle wasting. Although the biological origin
Externí odkaz:
https://doaj.org/article/dffd91e077b74473be10610053a34c06
Autor:
Yoshitsugu Aoki, Cristina S. J. Rocha, Taavi Lehto, Shouta Miyatake, Henrik Johansson, Yasumasa Hashimoto, Joel Z. Nordin, Imre Mager, Misako Aoki, McClorey Graham, Chaitra Sathyaprakash, Thomas C. Roberts, Matthew J. A. Wood, Mark A. Behlke, Samir El Andaloussi
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Splice-switching antisense oligonucleotide- (SSO-) mediated correction of framedisrupting mutation-containing premessenger RNA (mRNA) transcripts using exon skipping is a highly promising treatment method for muscular diseases such as Duchenne muscul
Externí odkaz:
https://doaj.org/article/0ea4440e5f7542ee82645e95690437a3
Autor:
Daniel W. Hagey, Maximilian Kordes, André Görgens, Metoboroghene O. Mowoe, Joel Z. Nordin, Carlos Fernández Moro, J.‐Matthias Löhr, Samir EL Andaloussi
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 12, Pp n/a-n/a (2021)
Abstract Up to now, the field of liquid biopsies has focused on circulating tumour DNA and cells, though extracellular vesicles (EVs) have been of increasing interest in recent years. Thus, reported sources of tumour‐derived nucleic acids include l
Externí odkaz:
https://doaj.org/article/7da1754bd96c4fbb8751c3cd8bf11ab9
Autor:
Dhanu Gupta, Xiuming Liang, Svetlana Pavlova, Oscar P.B Wiklander, Giulia Corso, Ying Zhao, Osama Saher, Jeremy Bost, Antje M. Zickler, Andras Piffko, Cecile L. Maire, Franz L. Ricklefs, Oskar Gustafsson, Virginia Castilla Llorente, Manuela O. Gustafsson, R. Beklem Bostancioglu, Doste R Mamand, Daniel W. Hagey, André Görgens, Joel Z. Nordin, Samir EL Andaloussi
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Extracellular vesicles (EVs) are naturally occurring nano-sized carriers that are secreted by cells and facilitate cell-to-cell communication by their unique ability to transfer biologically active cargo. Despite the pronounced increase in our unders
Externí odkaz:
https://doaj.org/article/58968a8488ad421eab477de1aa07f81f