Zobrazeno 1 - 10
of 885
pro vyhledávání: '"Joel Z"'
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Abstract Background and main body Pharmacokinetics (PK) and pharmacodynamics (PD) are central concepts to guide the dosage and administration of drug therapies and are essential to consider for both healthcare professionals and researchers in therape
Externí odkaz:
https://doaj.org/article/56c04af6edb64a13b86f110e4d4e7302
Autor:
Doste R. Mamand, Safa Bazaz, Dara K. Mohammad, Xiuming Liang, Svetlana Pavlova, Carsten Mim, Susanne Gabrielsson, Joel Z. Nordin, Oscar P. B. Wiklander, Manuchehr Abedi‐Valugerdi, Samir EL‐Andaloussi
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Haematopoiesis dysregulation with the presence of immature myeloid and erythroid immunosuppressive cells are key characteristics of the immune escape phase of tumour development. Here, the role of in vitro generated B16F10 tumour cell‐deri
Externí odkaz:
https://doaj.org/article/1c7ed4f843a74655872ea6309bf7b745
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0300024 (2024)
Today, with the advent of Large-scale generative Language Models (LLMs) it is now possible to simulate free responses to interview questions such as those traditionally analyzed using qualitative research methods. Qualitative methodology encompasses
Externí odkaz:
https://doaj.org/article/607401a44b77487f9500b83e7e806de4
Autor:
Wenyi Zheng, Julia Rädler, Helena Sork, Zheyu Niu, Samantha Roudi, Jeremy P. Bost, André Görgens, Ying Zhao, Doste R. Mamand, Xiuming Liang, Oscar P. B. Wiklander, Taavi Lehto, Dhanu Gupta, Joel Z. Nordin, Samir EL Andaloussi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Extracellular vesicles (EVs) are gaining ground as next-generation drug delivery modalities. Genetic fusion of the protein of interest to a scaffold protein with high EV-sorting ability represents a robust cargo loading strategy. To address
Externí odkaz:
https://doaj.org/article/622f51f2cad347f4917ee57145e74779
Publikováno v:
Frontiers in Computational Neuroscience, Vol 16 (2022)
Recent investigation on reinforcement learning (RL) has demonstrated considerable flexibility in dealing with various problems. However, such models often experience difficulty learning seemingly easy tasks for humans. To reconcile the discrepancy, o
Externí odkaz:
https://doaj.org/article/d18c86546aff43bba5651b8e74ec4b18
Autor:
Joel Z. Nordin
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 10, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/9c3b1aaa07904de7a747fed1b80cb49b
Autor:
Xiuming Liang, Zheyu Niu, Valentina Galli, Nathalie Howe, Ying Zhao, Oscar P. B. Wiklander, Wenyi Zheng, Rim Jawad Wiklander, Giulia Corso, Christopher Davies, Justin Hean, Eleni Kyriakopoulou, Doste R. Mamand, Risul Amin, Joel Z. Nordin, Dhanu Gupta, Samir EL Andaloussi
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 7, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) have shown promise as potential therapeutics for the treatment of various diseases. However, their rapid clearance after administration could be a limitation in certain therapeutic settings. To solve this, an eng
Externí odkaz:
https://doaj.org/article/9620878d96184d60a46da34441e162df
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009882 (2022)
Social learning, copying other's behavior without actual experience, offers a cost-effective means of knowledge acquisition. However, it raises the fundamental question of which individuals have reliable information: successful individuals versus the
Externí odkaz:
https://doaj.org/article/2bcc431db99840bb8af560441a3e0721
Autor:
William J. Valentine, Sherif A. Mostafa, Suzumi M. Tokuoka, Fumie Hamano, Natsuko F. Inagaki, Joel Z. Nordin, Norio Motohashi, Yoshihiro Kita, Yoshitsugu Aoki, Takao Shimizu, Hideo Shindou
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
In Duchenne muscular dystrophy (DMD), lack of dystrophin increases the permeability of myofiber plasma membranes to ions and larger macromolecules, disrupting calcium signaling and leading to progressive muscle wasting. Although the biological origin
Externí odkaz:
https://doaj.org/article/dffd91e077b74473be10610053a34c06
Cultural accumulation drives the open-ended and diverse progress in capabilities spanning human history. It builds an expanding body of knowledge and skills by combining individual exploration with inter-generational information transmission. Despite
Externí odkaz:
http://arxiv.org/abs/2406.00392