Canakinumab in addition to phosphate-binding and phosphaturia-inducing therapy were effective in achieving remission in a child with a large familial calcinotic tumour

Autor: Maria Ochoa, Roman Jurencak, Kevin Smit, Sasha Carsen, Sarah L. Sawyer, Marie-Eve Robinson, Karine Khatchadourian, Hooi Peng Cheng, Marika Pagé, Joel Werier, Leanne Marie Ward

Publikováno v: Bone Reports, Vol 19, Iss , Pp 101695- (2023)

We describe the clinical evolution of a patient with tumoral calcinosis due to a pathogenic variant in the GALNT3 gene presented with a large mass overlying her left hip associated complicated by inflammatory flares. Therapy (sevelamer, acetazolamide

Externí odkaz: https://doaj.org/article/8263dfb12562465cac43ce38dde4da34

Oncolytic Rhabdovirus Vaccine Boosts Chimeric Anti-DEC205 Priming for Effective Cancer Immunotherapy

Autor: Fanny Tzelepis, Harsimrat Kaur Birdi, Anna Jirovec, Silvia Boscardin, Christiano Tanese de Souza, Mohsen Hooshyar, Andrew Chen, Keara Sutherland, Robin J. Parks, Joel Werier, Jean-Simon Diallo

Publikováno v: Molecular Therapy: Oncolytics, Vol 19, Iss , Pp 240-252 (2020)

Prime-boost vaccination employing heterologous viral vectors encoding an antigen is an effective strategy to maximize the antigen-specific immune response. Replication-deficient adenovirus serotype 5 (Ad5) is currently being evaluated clinically in N

Externí odkaz: https://doaj.org/article/85c0f1ffc30c4c7e93249fbf227e89f3

Immunotherapy for sarcomas: new frontiers and unveiled opportunities

Autor: Carolyn Nessim, Jean-Simon Diallo, Harsimrat Kaur Birdi, Anna Jirovec, Serena Cortés-Kaplan, Joel Werier, Michele Ardolino

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)

Sarcomas are a rare malignancy of mesenchymal tissues, comprizing a plethora of unique subtypes, with more than 60 types. The sheer heterogeneity of disease phenotype makes this a particularly difficult cancer to treat. Radiotherapy, chemotherapy and

Externí odkaz: https://doaj.org/article/e1fe72d8937549b89ab948186d980f96

Future directions for bone metastasis research – highlights from the 2015 bone and the Oncologist new updates conference (BONUS)

Autor: Ricardo Fernandes, Peter Siegel, Svetlana Komarova, John Hilton, Christina Addison, Mohammed F K Ibrahim, Joel Werier, Kristopher Dennis, Gurmit Singh, Eitan Amir, Virginia Jarvis, Urban Emmenegger, Sasha Mazzarello, Mark Clemons

Publikováno v: Journal of Bone Oncology, Vol 5, Iss 2, Pp 57-62 (2016)

In an era of reduced peer-reviewed grant funding, performing academic bone oncology-related research has become increasingly challenging. Over the last 10 years we have held an annual meeting to bring together clinicians, clinician/scientists and bas

Externí odkaz: https://doaj.org/article/91847d7add75472587f4072b65e6f60b

The role of chemotherapy and radiotherapy in localized extraskeletal osteosarcoma

Autor: Marilyn Heng, Abha Gupta, Peter W. Chung, John H. Healey, Max Vaynrub, Peter S. Rose, Matthew T. Houdek, Patrick P. Lin, Andrew J. Bishop, Francis J. Hornicek, Yen-Lin Chen, Santiago Lozano-Calderon, Ginger E. Holt, Ilkyu Han, David Biau, Xiaohui Niu, Nicholas M. Bernthal, Peter C. Ferguson, Jay S. Wunder, Takafumi Ueda, Shigeki Kakunaga, Akira Kawai, Hideshi Sugiura, Teruki Kidani, Toshiyuki Kunisasa, Toshifumi Ozaki, Keisuke Ae, Akihito Nagano, Takatoshi Ohno, Koji Hiraoka, Norio Yamamoto, Hiroyuki Tsuchiya, Yoshihiro Matsumoto, Takashi Yanagawa, Robart Nakayama, Hideo Morioka, Tadahiko Kubo, Shoji Simose, Yoshiki Yamagami, Tetsuji Yamamoto, Motohiro Kawasaki, Tomoaki Torigoe, Yasuo Yazawa, Toru Akiyama, Tabu Gokita, Jun Manabe, Mitsunori Kaya, Makoto Emori, Tomoki Nakamura, Akihiko Matsumine, Shinsuke Sugihara, Masahiro Yokouchi, Setsuro Komiya, Yoshiyuki Suehara, Tatsuya Takagi, Teruya Kawamoto, Junji Wasa, Tsukasa Yonemoto, Takeshi Ishii, Ichiro Baba, Manabu Hoshi, Kenichiro Hamada, Norifumi Naka, Tsukasa Sotobori, Nobuhito Araki, Tomotake Okuma, Takahiro Goto, Hiroshi Kobayashi, Hirotaka Kawano, Masami Hosaka, Hiroyuki Futani, Hiroaski Hiraga, Yoshihiro Nishida, Anthony Griffin, Albiruni R.Abdul Razak, David Benjamin Shultz, Charles Catton, Steven Robinson, Shreyaskumar R. Patel, Valerae O. Lewis, B. Ashleigh Guadagnolo, Thomas DeLaney, Haotong Wang, Kevin Raskin, Alexandra K. Callan, Robert Henshaw, Marc Isler, Sophie Mottard, Wei-Ming Chen, Frank Traub, Tom Wei-Wu Chen, Robert E. Turcotte, Darin Davidson, Per-Ulf Tunn, Herbert Loong, Michelle Ghert, Joel Werier, Paul Clarkson, John A. Abraham

Publikováno v: Eur J Cancer

Purpose The role of chemotherapy (CT) and radiotherapy (RT) for management of extraskeletal osteosarcoma (ESOS) remains controversial. We examined disease outcomes for ESOS patients and investigated the association between CT/RT with recurrence and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a997f1a26c6656bd43f2838eb237005
https://doi.org/10.1016/j.ejca.2019.07.029