Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Joel Tocker"'
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Using computational approaches, Nuzzo et al. identify 983 potential metabolite–human target interactions from the Inflammatory Bowel Disease (IBD) cohort dataset of the Human Microbiome Project 2 (HMP2) and public databases. These predicted interac
Externí odkaz:
https://doaj.org/article/75f87b3c80b74ee3b132d5f3e4bd2ef1
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The cytokine TNFSF14 [homologous to Lymphotoxin, exhibits Inducible expression and competes with HSV Glycoprotein D for binding to HVEM, a receptor expressed on T lymphocytes (LIGHT)] has been shown in mouse models to be important for development of
Externí odkaz:
https://doaj.org/article/1bca2ea52ebe4404ab035089c1640516
Autor:
Sharon Wannberg, James B. Rottman, Sabine S. Escobar, Joel Tocker, Daniela Metz, Michael R. Comeau, Deanna Mohn, Kira Misura, Alison L. Budelsky, Anh Leith, Erika Rickel, Lori Siegel, John K. Sullivan, Cynthia R. Willis
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 53:810-821
Asthma is a heterogeneous disease characterized by airway inflammation and hyperreactivity. IL-17 receptor A (IL-17RA) is a shared receptor subunit required for activity of IL-17 family cytokines, including IL-17A and IL-25. IL-17A and IL-25 induce d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78763ed5ddd89dd9cd34f2e246eb178f
https://doi.org/10.1165/rcmb.2015-0038oc
https://doi.org/10.1165/rcmb.2015-0038oc
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
The cytokine TNFSF14 [homologous to Lymphotoxin, exhibits Inducible expression and competes with HSV Glycoprotein D for binding to HVEM, a receptor expressed on T lymphocytes (LIGHT)] has been shown in mouse models to be important for development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3b6fb14bd34551ecf4a25edf03488d
http://europepmc.org/articles/PMC5868327
http://europepmc.org/articles/PMC5868327
Publikováno v:
The Journal of allergy and clinical immunology. 141(1)
Background Food allergy (FA) is an increasing problem that has no approved treatment. The pro-T H 2 cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) are associated with FA, and mAbs to these cytokines are reported to suppress murine FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffa40ae242c34e3322aae1210c1ea65
https://pubmed.ncbi.nlm.nih.gov/28552763
https://pubmed.ncbi.nlm.nih.gov/28552763
Autor:
Taku Kambayashi, Steven A. Saenz, Joel Tocker, Alison L. Budelsky, Melanie A. Kleinschek, Robert A. Kastelein, David Artis, Joseph F. Urban, Avinash Bhandoola, Jacqueline G. Perrigoue, Sean P. Spencer, Mark C. Siracusa
Publikováno v:
Nature
Type-2 immunity, the ancient defence mechanism that provides protection against gastrointestinal helminth infections, involves the recruitment of T helper (TH) cells that produce immune mediators or cytokines to coordinate an immune response involvin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c13a037da5bf9759657c40a7dd1e4f6
http://europepmc.org/articles/PMC2861732
http://europepmc.org/articles/PMC2861732
Autor:
Fergus R. Byrne, Aaron Winters, David Brankow, Sylvia Hu, Todd Juan, Shirley Steavenson, George Doellgast, Kamesh Kuchimanchi, Heather Brown, Sharon Anderson, Sara Smelt, Tim Sullivan, Dina Alcorn, Joel Tocker, Charley Dean, John Macmaster, Jacqueline Kirchner, Janet Buys, Raffi Manoukian, Eric Jiao, Xiaoming Zou, Gabriele S. Campanella, Gerald Siu
Publikováno v:
Autoimmunity. 42:171-182
IP-10 secretion is induced by pro-inflammatory cytokines and mediates the migration of CXCR3+ cells. Its elevation in clinical samples has been associated with multiple inflammatory diseases and its antagonism has been reported to be effective in sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3bb11d9e9915a2f393e6d3f20007095
https://doi.org/10.1080/08916930802629547
https://doi.org/10.1080/08916930802629547
Autor:
Wade Sigurdson, David Swart, Joel Tocker, Nilgun Isik, Amarnath Maitra, Walter Hanel, Fang Shen, Jill M. Kramer, James P. Malone, Sarah L. Gaffen, Tian Jin
Publikováno v:
Scopus-Elsevier
IL-17 is the hallmark cytokine of the newly described “Th17” lymphocyte population. The composition, subunit dynamics, and ligand contacts of the IL-17 receptor are poorly defined. We previously demonstrated that the IL-17RA subunit oligomerizes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b43c201cc5a2dd60c727ce50fe4886
https://doi.org/10.4049/jimmunol.179.10.6379
https://doi.org/10.4049/jimmunol.179.10.6379
Autor:
Yanqing Chen, Joshua Wertheimer, Joel Tocker, Patrick Branigan, Huiqing Liu, Daniel Horowitz, Matthew J. Loza, Frédéric Baribaud
Publikováno v:
3.2 Airway Cell Biology and Immunopathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b69dbc0c01338b3361fc22b622d727dd
https://doi.org/10.1183/13993003.congress-2015.pa878
https://doi.org/10.1183/13993003.congress-2015.pa878
Autor:
Dean Toy, Tim Vanden Bos, Martin F. Wolfson, David G. Kugler, Jesse L. Gurgel, Jonathan M.J. Derry, Jacques J. Peschon, Joel Tocker
Publikováno v:
The Journal of Immunology. 177:36-39
IL-17 is an inflammatory cytokine produced primarily by a unique lineage of CD4 T cells that plays critical roles in the pathogenesis of multiple autoimmune diseases. IL-17RA is a ubiquitously expressed receptor that is essential for IL-17 biologic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e5cdadb41ba16fad5a1ef2a509fe58
https://doi.org/10.4049/jimmunol.177.1.36
https://doi.org/10.4049/jimmunol.177.1.36