Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joel S. Britson"'
Autor:
M Willian, Joel S. Britson, R Timmons, Justin M. Balko, J L Bryant, Esther P. Black, Andrey Frolov
Publikováno v:
British Journal of Cancer
Background: Treatment with epidermal growth factor receptor (EGFR) inhibitors can result in clinical response in non-small-cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC) for some unselected patients. EGFR and KRAS mutation statu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6960175ac90cc107e67a335eed52e4
https://doi.org/10.1038/bjc.2011.465
https://doi.org/10.1038/bjc.2011.465
Publikováno v:
Biochemical and biophysical research communications. 390(3)
Lung cancers demonstrate loss of cellular signaling control pathways. EGFR-mutant non-small cell lung cancer cell lines constitutively express active ERK1/2 and require ERK activity for survival. DUSP4 is a negative regulator of ERK activity and is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a441338f9cf0781645a9c130051b8f
https://pubmed.ncbi.nlm.nih.gov/19836351
https://pubmed.ncbi.nlm.nih.gov/19836351
Autor:
Andrey Frolov, Michael C. Willian, Esther P. Black, Joel S. Britson, Virginia L. Coakley, Justin M. Balko
Publikováno v:
Cancer Research. 69:B74-B74
Purpose: The intent of the study described herein is to develop and characterize a microRNA gene expression signature of response to EGFR inhibition portable to solid tumors for which treatment with an EGFR inhibitor is indicated. Experimental Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a85ca5d24177a8e26c06539b9031adef
https://doi.org/10.1158/0008-5472.fbcr09-b74
https://doi.org/10.1158/0008-5472.fbcr09-b74