Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Joel Ross"'
Autor:
Joseph Lucas, Holly K Dressman, Sunil Suchindran, Mai Nakamura, Nelson J Chao, Heather Himburg, Kerry Minor, Gary Phillips, Joel Ross, Majid Abedi, Robert Terbrueggen, John P Chute
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107897 (2014)
Terrorism using radiological dirty bombs or improvised nuclear devices is recognized as a major threat to both public health and national security. In the event of a radiological or nuclear disaster, rapid and accurate biodosimetry of thousands of po
Externí odkaz:
https://doaj.org/article/b14f6ebb02c84a37840150e2793ea2a9
Autor:
Muhammad Faheem, Eric Deneault, Roumiana Alexandrova, Deivid C. Rodrigues, Giovanna Pellecchia, Carole Shum, Mehdi Zarrei, Alina Piekna, Wei Wei, Jennifer L. Howe, Bhooma Thiruvahindrapuram, Sylvia Lamoureux, P. Joel Ross, Clarrisa A. Bradley, James Ellis, Stephen W. Scherer
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background The X-linked PTCHD1 locus is strongly associated with autism spectrum disorder (ASD). Males who carry chromosome microdeletions of PTCHD1 antisense long non-coding RNA (PTCHD1-AS)/DEAD-box helicase 53 (DDX53) have ASD, or a sub-cl
Externí odkaz:
https://doaj.org/article/ad5d028dd05343348ea7357073f240f8
Autor:
Tyler Joel Ross, Jun Zhang
Publikováno v:
Microorganisms, Vol 11, Iss 2, p 288 (2023)
Cancer continues to be a significant source of mortality and morbidity worldwide despite progress in cancer prevention, early detection, and treatment. Fortunately, immunotherapy has been a breakthrough in the treatment of many cancers. However, the
Externí odkaz:
https://doaj.org/article/89fe9cc544a24c418fd27ae7fe37eb80
Autor:
Ameet S. Sengar, Hongbin Li, Wenbo Zhang, Celeste Leung, Arun K. Ramani, Ner Mu Saw, Yongqian Wang, YuShan Tu, P. Joel Ross, Stephen W. Scherer, James Ellis, Michael Brudno, Zhengping Jia, Michael W. Salter
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4285-4294.e5 (2019)
Summary: NMDA receptors (NMDARs) are critical for physiological synaptic plasticity, learning, and memory and for pathological plasticity and neuronal death. The GluN1 subunit is encoded by a single gene, GRIN1, with 8 splice variants, but whether th
Externí odkaz:
https://doaj.org/article/1a3dd25900664f94b5b66e9ce5d99a4e
Autor:
Joel Ross, Izhar Hasan
Publikováno v:
Inflammopharmacology.
Autor:
Ugljesa Djuric, Aaron Y.L. Cheung, Wenbo Zhang, Rebecca S. Mok, Wesley Lai, Alina Piekna, Jason A. Hendry, P. Joel Ross, Peter Pasceri, Dae-Sung Kim, Michael W. Salter, James Ellis
Publikováno v:
Neurobiology of Disease, Vol 76, Iss , Pp 37-45 (2015)
MECP2 mutations cause the X-linked neurodevelopmental disorder Rett Syndrome (RTT) by consistently altering the protein encoded by the MECP2e1 alternative transcript. While mutations that simultaneously affect both MECP2e1 and MECP2e2 isoforms have b
Externí odkaz:
https://doaj.org/article/e0838b9791d644dcbf603d7327d5b907
Publikováno v:
Translational Psychiatry. 12
NMDA receptors (NMDARs), a prominent subtype of glutamatergic receptors, are implicated in the pathogenesis and development of neuropsychiatric disorders such as epilepsy, intellectual disability, autism spectrum disorder, and schizophrenia, and are
Publikováno v:
University of Bristol-PURE
This paper focuses on the development, delivery and preliminary impact analysis of an engineering Work Experience Week (WEW) programme for KS4 students in the School of Civil, Aerospace and Mechanical Engineering (CAME) at the University of Bristol,
Autor:
James Ellis, P. Joel Ross, Brandon S. Smith, Marat Mufteev, Deivid C. Rodrigues, Rebecca S.F. Mok, Stephen W. Scherer
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-14 (2020)
Molecular Autism
Molecular Autism
Genetic factors contribute to the development of autism spectrum disorder (ASD), and although non-protein-coding regions of the genome are being increasingly implicated in ASD, the functional consequences of these variants remain largely uncharacteri
Autor:
Alina Piekna, Michael W. Salter, Eric Deneault, Stephen W. Scherer, Peter Pasceri, Wei Wei, Tadeo Thompson, James Ellis, P. Joel Ross, Fraser P. McCready, Deivid C. Rodrigues, Kirill Zaslavsky, Wen-Bo Zhang, Melody Zhao, Joelle El Hajjar, Caitlin Loo, Zhuozhi Wang, Marat Mufteev, Shahryar Khattak, Asli Romm
Publikováno v:
Nature neuroscience
Heterozygous loss-of-function mutations in SHANK2 are associated with autism spectrum disorder (ASD). We generated cortical neurons from induced pluripotent stem cells (iPSC) derived from neurotypic and ASD-affected donors. We developed Sparse cocult