Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joel Ramos da Palma"'
Publikováno v:
Viruses, Vol 4, Iss 10, Pp 2162-2181 (2012)
Arenaviruses include lethal human pathogens which pose serious public health threats. So far, no FDA approved vaccines are available against arenavirus infections, and therapeutic options are limited, making the identification of novel drug targets f
Externí odkaz:
https://doaj.org/article/bcf0b377910047479f7a24d7f25badb0
Autor:
Marco Salamina, Nabil G. Seidah, Laura Cendron, Stefan Kunz, Antonella Pasquato, Joel Oppliger, Dominique J. Burri, Joel Ramos da Palma, Patrizia Polverino de Laureto
Publikováno v:
Journal of Biological Chemistry. 289:35743-35756
The proprotein convertase subtilisin kexin isozyme 1 (SKI-1)/site 1 protease (S1P) plays crucial roles in cellular homeostatic functions and is hijacked by pathogenic viruses for the processing of their envelope glycoproteins. Zymogen activation of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd042825bb7abab34f69910566bebdb
https://doi.org/10.1074/jbc.m114.588525
https://doi.org/10.1074/jbc.m114.588525
Autor:
Antonella Pasquato, Joel Ramos da Palma, Stefan Kunz, Christina F. Spiropoulou, Eric Bergeron, Dominique J. Burri, Abdel-Majid Khatib, Joel Oppliger
Publikováno v:
Journal of Virology, vol. 90, no. 2, pp. 705-714
Journal of virology
Journal of virology
Arenaviruses are emerging viruses including several causative agents of severe hemorrhagic fevers in humans. The advent of next-generation sequencing technology has greatly accelerated the discovery of novel arenavirus species. However, for many of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b2c6d5613d76d1cad354ad547d2cb8
https://serval.unil.ch/resource/serval:BIB_B7ABE25892BF.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_B7ABE25892BF.P001/REF.pdf
Publikováno v:
The Journal of biological chemistry. 291(5)
The proprotein convertase subtilisin kexin isozyme-1 (SKI-1)/site-1 protease (S1P) is implicated in lipid homeostasis, the unfolded protein response, and lysosome biogenesis. The protease is further hijacked by highly pathogenic emerging viruses for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e324e5187fff86739643fdcc86704214
https://pubmed.ncbi.nlm.nih.gov/26645686
https://pubmed.ncbi.nlm.nih.gov/26645686
Autor:
Antonella Pasquato, Stephan Ölschläger, Andreas Bergthaler, Boris P.-L. Lee, Leticia Barba, Joel Ramos da Palma, Lukas Flatz, Rami Sommerstein
Publikováno v:
Journal of virology. 88(15)
A key characteristic of arenaviruses is their ability to establish persistent infection in their natural host. Different factors like host age, viral dose strain, and route of infection may contribute to the establishment of persistence. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c8390c51e67fc5a6a41d19321f336c
https://pubmed.ncbi.nlm.nih.gov/24829355
https://pubmed.ncbi.nlm.nih.gov/24829355
Autor:
Michael B. A. Oldstone, Sébastien Igonet, Stefan Kunz, Antonella Pasquato, Joel Ramos da Palma, Dominique J. Burri
Publikováno v:
Virology, vol. 436, no. 1, pp. 127-133
Virology
Virology
Maturation of the arenavirus GP precursor (GPC) involves proteolytic processing by cellular signal peptidase and the proprotein convertase subtilisin kexin isozyme 1 (SKI-1)/site 1 protease (S1P), yielding a tripartite complex comprised of a stable s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca1154bbceaa4f78c02387858f15a52
https://serval.unil.ch/notice/serval:BIB_7DE57711738A
https://serval.unil.ch/notice/serval:BIB_7DE57711738A
Publikováno v:
Antiviral research
The proprotein convertases (PCs) are a family of nine mammalian enzymes that play key roles in the maintenance of cell homeostasis by activating or inactivating proteins via limited proteolysis under temporal and spatial control. A wide range of path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e35d5b2becd17ed72140b9a5ab5376