Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joel R. Greenbowe"'
Autor:
Naiyer A. Rizvi, Marc Ladanyi, Mark G. Kris, Vincent A. Miller, Doron Lipson, Phil Stephens, Jeffrey S. Ross, Joel R. Greenbowe, Sohail Balasubramanian, Maria E. Arcila, Lu Wang, Alexander Drilon
Supplementary Table 1. Mutation hotspots interrogated by Sequenom.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f8c62efa7e2dd632c90d4a3ce779fb
https://doi.org/10.1158/1078-0432.22457910.v1
https://doi.org/10.1158/1078-0432.22457910.v1
Autor:
Naiyer A. Rizvi, Marc Ladanyi, Mark G. Kris, Vincent A. Miller, Doron Lipson, Phil Stephens, Jeffrey S. Ross, Joel R. Greenbowe, Sohail Balasubramanian, Maria E. Arcila, Lu Wang, Alexander Drilon
Supplementary Figure 1. Distribution of median exon coverage depths for the samples included in this study, all passing the minimum threshold of 250x with an average median exon coverage depth >700x. Supplementary Figure 2. Median exon coverage depth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c2acf9b4db383159bcca50c9db3a53
https://doi.org/10.1158/1078-0432.22457913.v1
https://doi.org/10.1158/1078-0432.22457913.v1
Autor:
Naiyer A. Rizvi, Marc Ladanyi, Mark G. Kris, Vincent A. Miller, Doron Lipson, Phil Stephens, Jeffrey S. Ross, Joel R. Greenbowe, Sohail Balasubramanian, Maria E. Arcila, Lu Wang, Alexander Drilon
Purpose: Broad, hybrid capture–based next-generation sequencing (NGS), as a clinical test, uses less tissue to identify more clinically relevant genomic alterations compared with profiling with multiple non-NGS tests. We set out to determine the fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fc7d2c2c7a6c2e8554d5eef09ef3de
https://doi.org/10.1158/1078-0432.c.6523749
https://doi.org/10.1158/1078-0432.c.6523749
Autor:
Roy S. Herbst, Joel R. Greenbowe, Ximing Tang, Jing Wang, Nana E. Hanson, Waun Ki Hong, Pamela Villalobos, John D. Minna, Julie G. Izzo, Huiqin Chen, Neda Kalhor, Li Shen, Carmen Behrens, Barbara Mino, J. Jack Lee, Garrett M. Frampton, Jaime Rodriguez-Canales, Vincent A. Miller, Vassiliki A. Papadimitrakopoulou, Luc Girard, Lixia Diao, Ignacio I. Wistuba, James Sun, Dennis Ruder, Veera Baladandayuthapani, Kazuhiko Shien
Publikováno v:
Oncotarget. 9:33995-34008
Despite a therapeutic paradigm shift into targeted-driven medicinal approaches, resistance to therapy remains a hallmark of lung cancer, driven by biological and molecular diversity. Using genomic and expression data from advanced non-small cell lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8ca6927533d4e117a94d6d7db15b9ba
https://doi.org/10.18632/oncotarget.26129
https://doi.org/10.18632/oncotarget.26129
Autor:
Thomas J. George, Kyle Gowen, Joel R. Greenbowe, Siraj M. Ali, Phillip J. Stephens, David Fabrizio, Alexa B. Schrock, Garrett M. Frampton, Jeffrey S. Ross, Richard F. Dunne, Samuel J. Klempner, Vincent A. Miller, Marwan Fakih, James Sun, Aram F. Hezel, Mark Kennedy
Publikováno v:
Journal of Gastrointestinal Oncology. 9:610-617
Background: The clinical application of PD1/PD-L1 targeting checkpoint inhibitors in colorectal cancer (CRC) has largely focused on a subset of microsatellite instable (MSI-high) patients. However, the proposed genotype that sensitizes these patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92b5c834220f4b3f880621cc7936e03
https://doi.org/10.21037/jgo.2018.05.06
https://doi.org/10.21037/jgo.2018.05.06
Autor:
Anil K. Dasyam, Inderpal S. Sarkaria, Siraj M. Ali, Jeffrey S. Ross, Khanh Nguyen, Jon Chung, Marina N. Nikiforova, Jill Lacy, Nathan Bahary, Jamie Koo, Andrew Eugene Hendifar, Aatur D. Singhi, Herbert J. Zeh, Joel R. Greenbowe
Publikováno v:
Journal of the National Comprehensive Cancer Network. 15:555-562
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, with a 5-year survival of 8%. Current therapeutic regimens are largely ineffective and underscore the need for novel treatment strategies. Chromosomal rearrangements involving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e34d2c5c216d9564d0d1ca9189ff53b
https://doi.org/10.6004/jnccn.2017.0058
https://doi.org/10.6004/jnccn.2017.0058
Autor:
Hye Ryun Kim, Eun Kyung Kim, Byoung Chul Cho, S. M. Kim, Minkyu Jung, Siraj M. Ali, H. N. Kang, Z. Zheng, Kee Yang Chung, Joel R. Greenbowe, Sang Joon Shin, S. G. Kim, C. W. Park, Hyun-Seok Kim, M. R. Yun, Sora Kim, T. M. Kim
Publikováno v:
Oncogene. 36:3334-3345
Despite remarkable progress in cutaneous melanoma genomic profiling, the mutational landscape of primary mucosal melanomas (PMM) remains unclear. Forty-six PMMs underwent targeted exome sequencing of 111 cancer-associated genes. Seventy-six somatic n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c242dc04f6e5f6a6fb372fdd6c9efd3
https://doi.org/10.1038/onc.2016.486
https://doi.org/10.1038/onc.2016.486
Autor:
Joel R. Greenbowe, Byoung Chul Cho, Seungtaek Lim, Hyun Chang, Hyo Sup Shim, Hye Ryun Kim, Eun Young Kim, Soonmyung Paik, Siraj M. Ali, Sun Min Lim
Publikováno v:
Oncotarget
// Sun Min Lim 1, 2 , Eun Young Kim 3 , Hye Ryun Kim 2 , Siraj M. Ali 4 , Joel R. Greenbowe 4 , Hyo Sup Shim 5 , Hyun Chang 6 , Seungtaek Lim 7 , Soonmyung Paik 8 , Byoung Chul Cho 2 1 Department of Internal Medicine, Division of Medical Oncology, CH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c9b94a1e803b560436e4cb59a96831
https://doi.org/10.18632/oncotarget.8138
https://doi.org/10.18632/oncotarget.8138
Autor:
Jeeyun Lee, Sora Kim, Hyo Song Kim, Hyun Cheol Chung, Siraj M. Ali, Byoung Chul Cho, Sangwoo Kim, Hyunki Kim, Jin-Hee Ahn, Sun Min Lim, Joel R. Greenbowe, Hyung Soon Park, In Seok Yang, Yoon-Koo Kang, Joo Hang Kim, Hye Ryun Kim, Nak Jung Kwon, Jae-Lyun Lee, Min Hee Ryu, Yong Wha Moon, Min Goo Lee
Publikováno v:
Oncotarget
ResearcherID
ResearcherID
// Sun Min Lim 1,2,* , Hyung Soon Park 3,* , Sangwoo Kim 4 , Sora Kim 4 , Siraj M. Ali 5 , Joel R. Greenbowe 5 , In Seok Yang 4 , Nak-Jung Kwon 6 , Jae Lyun Lee 7 , Min-Hee Ryu 7 , Jin-Hee Ahn 7 , Jeeyun Lee 8 , Min Goo Lee 3 , Hyo Song Kim 1 , Hyunk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029b1d948f0ecf95f7548daf9ddc13d6
http://europepmc.org/articles/PMC4891139
http://europepmc.org/articles/PMC4891139
Autor:
Talia Golan, Ben George, Jeffrey S. Ross, Anirban Maitra, Vincent A. Miller, Somak Roy, Andrew Eugene Hendifar, Joel R. Greenbowe, Samuel J. Klempner, Siraj M. Ali, Jon Chung, Javle Milind, Alexa B. Schrock, Amer H. Zureikat, Randall E. Brand, James Suh, Nathan Bahary, Aatur D. Singhi
Publikováno v:
Gastroenterology. 156(8)
Background & Aims It has been a challenge to select treatment for patients with pancreatic ductal adenocarcinomas (PDACs) based on genome alterations. We performed targeted genomic profile analyses of a large number of PDACs to assess the full spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8383efd2db9bd1953f47c0a26821bb
https://pubmed.ncbi.nlm.nih.gov/30836094
https://pubmed.ncbi.nlm.nih.gov/30836094