Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Joel Pekow"'
Autor:
Omar K. Jamil, Dustin Shaw, Zifeng Deng, Nicholas Dinardi, Natalie Fillman, Shivani Khanna, Noa Krugliak Cleveland, Atsushi Sakuraba, Christopher R. Weber, Russell D. Cohen, Sushila Dalal, Bana Jabri, David T. Rubin, Joel Pekow
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 16 (2023)
Background: Patients with primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) have an increased risk of developing colorectal neoplasia (CRN) in the proximal colon. Objectives: To evaluate whether duration and severity of inflam
Externí odkaz:
https://doaj.org/article/3cff1655a86949a1908bb1f1d315efaf
Autor:
Anthony Buisson, Lisa Cannon, Konstantin Umanskiy, Roger D. Hurst, Neil H. Hyman, Atsushi Sakuraba, Joel Pekow, Sushila Dalal, Russell D. Cohen, Bruno Pereira, David T. Rubin
Publikováno v:
Intestinal Research, Vol 20, Iss 3, Pp 303-312 (2022)
Background/Aims We assessed the effectiveness of anti-TNF agents and its associated factors to prevent endoscopic and clinical postoperative recurrence (POR) in Crohn’s disease (CD). Methods From a prospectively-maintained database, we retrieved 31
Externí odkaz:
https://doaj.org/article/fa7f5610473b4e348c07fe7abf41cdb6
Autor:
Fares Ayoub, Matthew Odenwald, Dejan Micic, Sushila R. Dalal, Joel Pekow, Russell D. Cohen, David T. Rubin, Atsushi Sakuraba
Publikováno v:
Intestinal Research, Vol 20, Iss 2, Pp 240-250 (2022)
Background/Aims Perianal fistulas are a debilitating manifestation of Crohn’s disease (CD). Despite the advent of anti-tumor necrosis factor (anti-TNF) therapy, the medical management of fistulizing CD continues to be challenged by unmet needs. We
Externí odkaz:
https://doaj.org/article/fa735fe1a21c49d4a6bd6f20c307f003
Autor:
Urszula Dougherty, Reba Mustafi, Hongyan Zhu, Xiaorong Zhu, Dilip Deb, Stephen C. Meredith, Fatma Ayaloglu-Butun, Michelle Fletcher, Arantxa Sanchez, Joel Pekow, Zifeng Deng, Nader Amini, Vani J Konda, Vijaya L. Rao, Atsushi Sakuraba, Akushika Kwesi, Sonia S Kupfer, Alessandro Fichera, Loren Joseph, John Hart, Fang He, Tong-Chuan He, Diana West-Szymanski, Yan Chun Li, Marc Bissonnette
Publikováno v:
Epigenetics, Vol 16, Iss 12, Pp 1317-1334 (2021)
Because ADAM17 promotes colonic tumorigenesis, we investigated potential miRNAs regulating ADAM17; and examined effects of diet and tumorigenesis on these miRNAs. We also examined pre-miRNA processing and tumour suppressor roles of several of these m
Externí odkaz:
https://doaj.org/article/acd55d7ef57b4fb5860f8bbd146ae130
Autor:
Xiao-Long Cui, Ji Nie, Jeremy Ku, Urszula Dougherty, Diana C. West-Szymanski, Francois Collin, Christopher K. Ellison, Laura Sieh, Yuhong Ning, Zifeng Deng, Carolyn W. T. Zhao, Anna Bergamaschi, Joel Pekow, Jiangbo Wei, Alana V. Beadell, Zhou Zhang, Geeta Sharma, Raman Talwar, Patrick Arensdorf, Jason Karpus, Ajay Goel, Marc Bissonnette, Wei Zhang, Samuel Levy, Chuan He
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
DNA 5-hydroxymethylcytosine (5hmC) modification is associated with gene transcription and used as a mark of mammalian development. Here the authors report a comprehensive 5hmC tissue map and analysis of 5hmC genomic distributions in 19 human tissues
Externí odkaz:
https://doaj.org/article/422a834f9ee54a78aa65900aafeb0d8b
Autor:
Dejan Micic, John N Gaetano, Jonah N Rubin, Russell D Cohen, Atsushi Sakuraba, David T Rubin, Joel Pekow
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182900 (2017)
Management of inpatients with inflammatory bowel disease (IBD) requires increasing resources. We aimed to identify factors associated with hospital readmissions among individuals with IBD.We collected data from the Healthcare Cost and Utilization Pro
Externí odkaz:
https://doaj.org/article/3846dd86e36a4de7b9e471581ce9d229
Autor:
Adam C Stein, John Nick Gaetano, Jeffrey Jacobs, Rangesh Kunnavakkam, Marc Bissonnette, Joel Pekow
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161523 (2016)
BACKGROUND AND AIMS:There is growing evidence that the incidence and severity of inflammatory bowel disease (IBD) may be geographically and seasonally related. Why these associations are observed remains unclear. We assessed the impact of geographic
Externí odkaz:
https://doaj.org/article/44267102ac1445b2a87858ad44ae488a
Autor:
Christopher G. Chapman, Joel Pekow
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 8 (2015)
Inflammatory bowel disease (IBD), comprised of ulcerative colitis and Crohn’s disease, is believed to develop as a result of a deregulated inflammatory response to environmental factors in genetically susceptible individuals. Despite advances in un
Externí odkaz:
https://doaj.org/article/6a7c32fca9cf4193be15f0863a806406
Autor:
Nathaniel A. Cohen, Joshua M. Steinberg, Alexa Silfen, Cindy Traboulsi, Tina G. Rodriguez, Jorie M. Singer, Shivani Patel, Russell D. Cohen, Sushila R. Dalal, Atsushi Sakuraba, Joel Pekow, Dejan Micic, David T. Rubin
Publikováno v:
Digestive Diseases and Sciences. 68:1464-1472
Autor:
Nathaniel A. Cohen, Maryam Zafer, Namrata Setia, Michael J. Anderson, Atsushi Sakuraba, Sushila Dalal, Joel Pekow, Russell D. Cohen, David T. Rubin, Dejan Micic
Publikováno v:
Digestive Diseases and Sciences. 68:897-901
Diagnosis of cytomegalovirus (CMV) colitis in the setting of severe ulcerative colitis (UC) remains a clinical challenge. This study aimed to determine the utility of serum CMV polymerase chain reaction (PCR) as a non-invasive test for the diagnosis