Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Joel O, Wertheim"'
Autor:
Steven Weaver, Vanessa M. Dávila Conn, Daniel Ji, Hannah Verdonk, Santiago Ávila-Ríos, Andrew J. Leigh Brown, Joel O. Wertheim, Sergei L. Kosakovsky Pond
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Molecular surveillance of viral pathogens and inference of transmission networks from genomic data play an increasingly important role in public health efforts, especially for HIV-1. For many methods, the genetic distance threshold used to connect se
Externí odkaz:
https://doaj.org/article/4224de6e5bd44b569093ce7fd9f1f999
Autor:
Tetyana I Vasylyeva, Jennifer L Havens, Jade C Wang, Elizabeth Luoma, Gabriel W Hassler, Helly Amin, Steve Di Lonardo, Faten Taki, Enoma Omoregie, Scott Hughes, Joel O Wertheim
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012288 (2024)
Socio-economic disparities were associated with disproportionate viral incidence between neighborhoods of New York City (NYC) during the first wave of SARS-CoV-2. We investigated how these disparities affected the co-circulation of SARS-CoV-2 variant
Externí odkaz:
https://doaj.org/article/156a9f53cf8c4be1b7a8f0f8c740000d
Autor:
Rocío Carrasco-Hernández, Humberto Valenzuela-Ponce, Maribel Soto-Nava, Claudia García-Morales, Margarita Matías-Florentino, Joel O. Wertheim, Davey M. Smith, Gustavo Reyes-Terán, Santiago Ávila-Ríos
Publikováno v:
Epidemics, Vol 47, Iss , Pp 100770- (2024)
In the context of infectious diseases, the dynamic interplay between ever-changing host populations and viral biology demands a more flexible modeling approach than common fixed correlations. Embracing random-effects regression models allows for a nu
Externí odkaz:
https://doaj.org/article/e72601382f21478f998acc6d52d4e853
Autor:
Anna Yakovleva, Ganna Kovalenko, Matthew Redlinger, Pavlo Smyrnov, Olga Tymets, Anna Korobchuk, Lyudmyla Kotlyk, Anna Kolodiazieva, Anna Podolina, Svitlana Cherniavska, Petro Antonenko, Steffanie A. Strathdee, Samuel R. Friedman, Ian Goodfellow, Joel O. Wertheim, Eric Bortz, Luke Meredith, Tetyana I. Vasylyeva
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Due to practical challenges associated with genetic sequencing in low-resource environments, the burden of hepatitis C virus (HCV) in forcibly displaced people is understudied. We examined the use of field applicable HCV sequencin
Externí odkaz:
https://doaj.org/article/838721fc514c4f04a847acc311a0d683
Autor:
Sepideh Mazrouee, Camden J. Hallmark, Ricardo Mora, Natascha Del Vecchio, Rocio Carrasco Hernandez, Michelle Carr, Marlene McNeese, Kayo Fujimoto, Joel O. Wertheim
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Detection of viral transmission clusters using molecular epidemiology is critical to the response pillar of the Ending the HIV Epidemic initiative. Here, we studied whether inference with an incomplete dataset would influence the accuracy of
Externí odkaz:
https://doaj.org/article/803d9ad4515f4042b2e2d6f79153c432
Autor:
Seth C Inzaule, Mark J Siedner, Susan J Little, Santiago Avila-Rios, Alisen Ayitewala, Ronald J Bosch, Vincent Calvez, Francesca Ceccherini-Silberstein, Charlotte Charpentier, Diane Descamps, Susan H Eshleman, Joseph Fokam, Lisa M Frenkel, Ravindra K Gupta, John P A Ioannidis, Pontiano Kaleebu, Rami Kantor, Seble G Kassaye, Sergei L Kosakovsky Pond, Vinie Kouamou, Roger D Kouyos, Daniel R Kuritzkes, Richard Lessells, Anne-Genevieve Marcelin, Lawrence Mbuagbaw, Brian Minalga, Nicaise Ndembi, Richard A Neher, Roger Paredes, Deenan Pillay, Elliot G Raizes, Soo-Yon Rhee, Douglas D Richman, Kiat Ruxrungtham, Pardis C Sabeti, Jonathan M Schapiro, Sunee Sirivichayakul, Kim Steegen, Wataru Sugiura, Gert U van Zyl, Anne-Mieke Vandamme, Annemarie M J Wensing, Joel O Wertheim, Huldrych F Gunthard, Michael R Jordan, Robert W Shafer
Publikováno v:
PLoS Medicine, Vol 20, Iss 9, p e1004293 (2023)
• Human immunodeficiency virus (HIV) drug resistance has implications for antiretroviral treatment strategies and for containing the HIV pandemic because the development of HIV drug resistance leads to the requirement for antiretroviral drugs that
Externí odkaz:
https://doaj.org/article/c16a34440b374c53938659e86b679144
Autor:
Jennifer L. Havens, Sébastien Calvignac-Spencer, Kevin Merkel, Sonia Burrel, David Boutolleau, Joel O. Wertheim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
There are competing hypotheses for human herpes simplex virus 2’s migration out-of-Africa. Here, the authors sequence 65 new herpes simplex virus 2 genomes with a focus on under-sampled sub-Saharan African countries, suggesting an Eastern African o
Externí odkaz:
https://doaj.org/article/818b3b2f50b843428833f7b013b3b207
Autor:
Anna Yakovleva, Ganna Kovalenko, Matthew Redlinger, Mariia G. Liulchuk, Eric Bortz, Viktoria I. Zadorozhna, Alla M. Scherbinska, Joel O. Wertheim, Ian Goodfellow, Luke Meredith, Tetyana I. Vasylyeva
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The use of real-time genomic epidemiology has enabled the tracking of the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), informing evidence-based public health decision making. Ukraine has experienced four wav
Externí odkaz:
https://doaj.org/article/c635c69deca64245b5068d94afcd08dc
Autor:
Edyth Parker, Catelyn Anderson, Mark Zeller, Ahmad Tibi, Jennifer L. Havens, Geneviève Laroche, Mehdi Benlarbi, Ardeshir Ariana, Refugio Robles-Sikisaka, Alaa Abdel Latif, Alexander Watts, Abdalla Awidi, Saied A. Jaradat, Karthik Gangavarapu, Karthik Ramesh, Ezra Kurzban, Nathaniel L. Matteson, Alvin X. Han, Laura D. Hughes, Michelle McGraw, Emily Spencer, Laura Nicholson, Kamran Khan, Marc A. Suchard, Joel O. Wertheim, Shirlee Wohl, Marceline Côté, Amid Abdelnour, Kristian G. Andersen, Issa Abu-Dayyeh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The dynamics of SARS-CoV-2 transmission in the Middle East have been relatively under-studied. Here, the authors integrate genomic and travel data and show that introductions to the region were initially driven by intercontinental air travel, after w
Externí odkaz:
https://doaj.org/article/33fdfa1926284ad094ec785f039d18fd
Autor:
Joel O. Wertheim, Jade C. Wang, Mindy Leelawong, Darren P. Martin, Jennifer L. Havens, Moinuddin A. Chowdhury, Jonathan E. Pekar, Helly Amin, Anthony Arroyo, Gordon A. Awandare, Hoi Yan Chow, Edimarlyn Gonzalez, Elizabeth Luoma, Collins M. Morang’a, Anton Nekrutenko, Stephen D. Shank, Stefan Silver, Peter K. Quashie, Jennifer L. Rakeman, Victoria Ruiz, Lucia V. Torian, Tetyana I. Vasylyeva, Sergei L. Kosakovsky Pond, Scott Hughes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here, the authors characterize a case of SARS-CoV-2 superinfection with Alpha and Epsilon variants, in which, via full genome sequencing analyses, they identify recombinant haplotypes in the spike, nucleocapsid, and ORF 8 coding regions, suggesting r
Externí odkaz:
https://doaj.org/article/c258b0e47c8e46188ea0732ebd024c24