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pro vyhledávání: '"Joel Nowitzke"'
Autor:
Joel Nowitzke, Ionel Popa
Publikováno v:
The Journal of Physical Chemistry Letters. 13:7139-7146
Both synthetic and natural protein-based materials are made of randomly oriented cross-linked molecules. Here we introduce a coarse-grained approach to estimate the average force-per-molecule for materials made from globular proteins. Our approach ha
Autor:
Marina Slawinski, Luai R. Khoury, Sabita Sharma, Joel Nowitzke, Jennifer H. Gutzman, Ionel Popa
Publikováno v:
ACS Biomaterials Science & Engineering. 8:1132-1142
Hydrogels made from globular proteins cross-linked covalently into a stable network are becoming an important type of biomaterial, with applications in artificial tissue design and cell culture scaffolds, and represent a promising system to study the
Publikováno v:
The Journal of Physical Chemistry B. 124:3283-3290
Binding-induced mechanical stabilization plays key roles in proteins involved in muscle contraction, cellular mechanotransduction, or bacterial adhesion. Because of the vector nature of force, single-molecule force spectroscopy techniques are ideal f
Publikováno v:
Macromolecules. 51:1441-1452
Protein-based hydrogels are unique materials that combine the durability and wetting properties of polymeric hydrogels with the biocompatibility and elasticity of proteins. Additionally, protein hydrogels present a promising system to probe the mecha
Several significant bacterial pathogens in humans secrete surface proteins that bind antibodies in order to protect themselves from the adaptive immune response and have evolved to operate under the mechanical sheer generated by mucus flow, coughing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6671753ba0bcd356f777d449e4d0d8
https://doi.org/10.1101/731059
https://doi.org/10.1101/731059
Publikováno v:
Biophysical Journal. 118:466a
Publikováno v:
J Vis Exp
Here, we describe a force-clamp rheometry method to characterize the biomechanical properties of protein-based hydrogels. This method uses an analog proportional-integral-derivative (PID) system to apply controlled-force protocols on cylindrical prot
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5171b10219106067afd63f93c84ceb4
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