Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Joel N. Kline"'
Autor:
Jennifer Toth, Joel N. Kline, Geoffrey Chupp, Jennifer Trevor, Gerard A. Silvestri, Michel Laviolette, Sundeep Bansal, Richard Tejedor, Nick Kahlstrom, Mark T. Dransfield, Andrew R. Haas, Charlene McEvoy, G. Mark Grubb, Jamie Hey, J. Scott Ferguson, Michael Simoff, Carla Lamb, Edmund McMullen, Momen M. Wahidi, Kyle B. Enfield, Sumita Khatri, Peter LaCamera, J. Mark FitzGerald, Adrian Shifren, Jennifer L. Olson, D. Kyle Hogarth, Mario Castro, Adnan Majid, Marc McClelland
Publikováno v:
Chest. 161:614-628
Background Bronchial thermoplasty is a device-based treatment for subjects ≥18 years with severe asthma poorly controlled with inhaled corticosteroids and long-acting beta-agonists. The Post-FDA Approval Clinical Trial Evaluating Bronchial Thermopl
Autor:
Joel N. Kline, Zuhair K. Ballas
Publikováno v:
Inflammatory Mechanisms in Allergic Diseases ISBN: 9780429134432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87ed00f2412fd3c74601068fbf6ff7e1
https://doi.org/10.1201/9780429134432-30
https://doi.org/10.1201/9780429134432-30
Autor:
Sandeep Bansal, Joel N. Kline, Charlene McEvoy, Michael Simoff, J. Ferguson, Sumita Khatri, D.K. Hogarth, Andrew R. Haas, Richard Tejedor, Edward Lawson, Mark T. Dransfield, Geoffrey Chupp, Michel Laviolette, Ron Olivenstein, Carla Lamb, Adrian Shifren, Momen M. Wahidi, Marc McClelland
Publikováno v:
Chest. 158:A12-A16
Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma
Autor:
Gary T. Ferguson, James Zangrilli, Ian Hirsch, Joel N. Kline, Njira L Lugogo, Frank Trudo, Mitchell Goldman, Geoffrey Chupp
Publikováno v:
Annals of Allergy, Asthma & Immunology. 122:478-485
Background Benralizumab is a unique eosinophil-depleting monoclonal antibody that significantly reduces asthma exacerbations, improves lung function and asthma symptoms, and permits the reduction of maintenance oral corticosteroid dosage for patients
Autor:
Geoffrey, Chupp, Joel N, Kline, Sumita B, Khatri, Charlene, McEvoy, Gerard A, Silvestri, Adrian, Shifren, Mario, Castro, Sundeep, Bansal, Marc, McClelland, Mark, Dransfield, Jennifer, Trevor, Nick, Kahlstrom, Michael, Simoff, Momen M, Wahidi, Carla R, Lamb, J Scott, Ferguson, Andrew, Haas, D Kyle, Hogarth, Richard, Tejedor, Jennifer, Toth, Jamie, Hey, Adnan, Majid, Peter, LaCamera, J Mark, Fitzgerald, Kyle, Enfield, G Mark, Grubb, Edmund A, McMullen, Jennifer L, Olson, Michel, Laviolette
Publikováno v:
Chest. 161(3)
Bronchial thermoplasty is a device-based treatment for subjects ≥ 18 years of age with severe asthma poorly controlled with inhaled corticosteroids and long-acting beta-agonists. The Post-FDA Approval Clinical Trial Evaluating Bronchial Thermoplast
Autor:
Joel N. Kline, Joseph Zabner
Publikováno v:
Chest. 155:659-661
Autor:
J. Mark FitzGerald, Richard Leigh, Joel N. Kline, Stephen Lam, Matthew J. Loza, Andreas Eich, Frédéric Baribaud, Patrick Berger, P. Chanez, Philip E. Silkoff, Dave Singh, Vedrana S. Susulic, Steven G. Kelsen, Elliot S. Barnathan, Michel Laviolette, Azra Hussaini, Irina Strambu, William J. Calhoun, Andrea Ludwig-Sengpiel, Geoffrey Chupp, Mark T. Dransfield, Vibeke Backer, Pierre Olivier Girodet, Celeste Porsbjerg
Publikováno v:
Journal of Allergy and Clinical Immunology. 140:710-719
Background The Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study profiled patients with mild, moderate, and severe asthma and nonatopic healthy control subjects. Objective We explored this data set to define type 2 inflammation b
Autor:
Joel N. Kline, Sanghun Choi, Ching-Long Lin, Alejandro P. Comellas, Eric A. Hoffman, Babak Haghighi, Jiwoong Choi, Nariman Jahani
Publikováno v:
Journal of Biomechanics. 56:102-110
The purpose of this study was to explore new insights in non-linearity, hysteresis and ventilation heterogeneity of asthmatic human lungs using four-dimensional computed tomography (4D-CT) image data acquired during tidal breathing. Volumetric image
Autor:
G.M. Grubb, Charlene McEvoy, Mark T. Dransfield, Andrew R. Haas, Jennifer Toth, E. Lawson, R. Kahlstrom, Kyle B. Enfield, Michael Simoff, Carla Lamb, Ron Olivenstein, Sandeep Bansal, Sumita Khatri, S. Ryan, D.K. Hogarth, JM FitzGerald, Richard Tejedor, Geoffrey Chupp, J.S. Ferguson, M. Laviolette, Momen M. Wahidi, Adrian Shifren, Guido Silvestri, Adnan Majid, Joel N. Kline, Marc McClelland, Mario Castro
Publikováno v:
B21. SEVERE ASTHMA: CLINICAL AND MECHANISTIC STUDIES.
Autor:
Philip N. Sanders, Isabella M. Grumbach, Anand M. Prasad, Joel N. Kline, Joseph Zabner, Omar A. Jaffer, Adam G. Rokita, Alan J. Ryan, Christopher J. Winters, Shubha Murthy, A. Brent Carter, Mark E. Anderson, Megan E. Dibbern
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Asthma is a disease of acute and chronic inflammation in which cytokines play a critical role in orchestrating the allergic inflammatory response. IL-13 and transforming growth factor (TGF)-β promote fibrotic airway remodeling, a major contributor t